Toxicity of the main electronic cigarette components, propylene glycol, glycerin, and nicotine, in Sprague-Dawley rats in a 90-day OECD inhalation study complemented by … B Phillips, B Titz, U Kogel, D Sharma, P Leroy, Y Xiang, G Vuillaume, ... Food and Chemical Toxicology 109, 315-332, 2017 | 135 | 2017 |
An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe−/− Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate … B Phillips, E Veljkovic, S Boué, WK Schlage, G Vuillaume, F Martin, B Titz, ... Toxicological Sciences 149 (2), 411-432, 2016 | 121 | 2016 |
Evaluation of the Tobacco Heating System 2.2. Part 4: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects compared with … ET Wong, U Kogel, E Veljkovic, F Martin, Y Xiang, S Boue, G Vuillaume, ... Regulatory Toxicology and Pharmacology 81, S59-S81, 2016 | 94 | 2016 |
A framework for in vitro systems toxicology assessment of e-liquids AR Iskandar, I Gonzalez-Suarez, S Majeed, D Marescotti, A Sewer, ... Toxicology Mechanisms and Methods 26 (6), 392-416, 2016 | 93 | 2016 |
A 28-day rat inhalation study with an integrated molecular toxicology endpoint demonstrates reduced exposure effects for a prototypic modified risk tobacco product compared … U Kogel, WK Schlage, F Martin, Y Xiang, S Ansari, P Leroy, ... Food and chemical toxicology 68, 204-217, 2014 | 81 | 2014 |
Effects of Cigarette Smoke, Cessation, and Switching to Two Heat-Not-Burn Tobacco Products on Lung Lipid Metabolism in C57BL/6 and Apoe−/− Mice—An … B Titz, S Boué, B Phillips, M Talikka, T Vihervaara, T Schneider, C Nury, ... Toxicological Sciences 149 (2), 441-457, 2016 | 79 | 2016 |
Characterization of the Vitrocell® 24/48 in vitroaerosol exposure system using mainstream cigarette smoke S Majeed, S Frentzel, S Wagner, D Kuehn, P Leroy, PA Guy, A Knorr, ... Chemistry Central Journal 8, 1-11, 2014 | 77 | 2014 |
Evaluation of the Tobacco Heating System 2.2. Part 6: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of a … A Oviedo, S Lebrun, U Kogel, J Ho, WT Tan, B Titz, P Leroy, G Vuillaume, ... Regulatory Toxicology and Pharmacology 81, S93-S122, 2016 | 71 | 2016 |
3-D nasal cultures: Systems toxicological assessment of a candidate modified-risk tobacco product AR Iskandar, C Mathis, F Martin, P Leroy, A Sewer, S Majeed, D Kuehn, ... ALTEX-Alternatives to animal experimentation 34 (1), 23-48, 2017 | 69 | 2017 |
A systems toxicology approach for comparative assessment: Biological impact of an aerosol from a candidate modified-risk tobacco product and cigarette smoke on human … AR Iskandar, C Mathis, WK Schlage, S Frentzel, P Leroy, Y Xiang, ... Toxicology in vitro 39, 29-51, 2017 | 65 | 2017 |
Impact assessment of cigarette smoke exposure on organotypic bronchial epithelial tissue cultures: a comparison of mono-culture and coculture model containing fibroblasts AR Iskandar, Y Xiang, S Frentzel, M Talikka, P Leroy, D Kuehn, E Guedj, ... Toxicological Sciences 147 (1), 207-221, 2015 | 62 | 2015 |
Systems toxicology assessment of the biological impact of a candidate modified risk tobacco product on human organotypic oral epithelial cultures F Zanetti, A Sewer, C Mathis, AR Iskandar, R Kostadinova, WK Schlage, ... Chemical research in toxicology 29 (8), 1252-1269, 2016 | 61 | 2016 |
Antiparasitic properties of leaf extracts derived from selected Nicotiana species and Nicotiana tabacum varieties SS Weber, KP Kaminski, JL Perret, P Leroy, A Mazurov, MC Peitsch, ... Food and Chemical Toxicology 132, 110660, 2019 | 57 | 2019 |
A six-month systems toxicology inhalation/cessation study in ApoE−/− mice to investigate cardiovascular and respiratory exposure effects of modified risk tobacco products, CHTP … B Phillips, J Szostak, B Titz, WK Schlage, E Guedj, P Leroy, G Vuillaume, ... Food and Chemical Toxicology 126, 113-141, 2019 | 51 | 2019 |
Comparative systems toxicology analysis of cigarette smoke and aerosol from a candidate modified risk tobacco product in organotypic human gingival epithelial cultures: A 3-day … F Zanetti, B Titz, A Sewer, GL Sasso, E Scotti, WK Schlage, C Mathis, ... Food and Chemical Toxicology 101, 15-35, 2017 | 46 | 2017 |
Toxicity of aerosols of nicotine and pyruvic acid (separate and combined) in Sprague–Dawley rats in a 28-day OECD 412 inhalation study and assessment of systems toxicology B Phillips, M Esposito, J Verbeeck, S Boué, A Iskandar, G Vuillaume, ... Inhalation toxicology 27 (9), 405-431, 2015 | 46 | 2015 |
A 6-month systems toxicology inhalation study in ApoE−/− mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared with cigarette smoke J Szostak, ET Wong, B Titz, T Lee, SK Wong, T Low, KM Lee, J Zhang, ... American Journal of Physiology-Heart and Circulatory Physiology 318 (3 …, 2020 | 45 | 2020 |
Alterations in serum polyunsaturated fatty acids and eicosanoids in patients with mild to moderate chronic obstructive pulmonary disease (COPD) B Titz, K Luettich, P Leroy, S Boue, G Vuillaume, T Vihervaara, K Ekroos, ... International journal of molecular sciences 17 (9), 1583, 2016 | 41 | 2016 |
A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version … BW Phillips, WK Schlage, B Titz, U Kogel, D Sciuscio, F Martin, P Leroy, ... Food and Chemical Toxicology 116, 388-413, 2018 | 40 | 2018 |
The biological effects of long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product M van der Toorn, A Sewer, D Marescotti, S Johne, K Baumer, D Bornand, ... Toxicology in Vitro 50, 95-108, 2018 | 37 | 2018 |