Articles with public access mandates - Fran PlattLearn more
OverallWellcomeNIHRoyal Society UKMRCNIHREuropean CommissionParkinson's UKDFGCancer Research UKCIHRBBSRCEPSRCMichael J Fox FoundationSNSFBHFDoDNHMRCINSERMNSERCDFFSwedish Research CouncilAlzheimers's UKARRSGovernment of ItalyFWFFWOEMBLVolkswagen FoundationDNRFSFICSIRTelethonFCTKnut and Alice Wallenberg FoundationDFIDNational Centre for the Replacement, Refinement and Reduction of Animals in Research, UKGovernment of SpainBMBFNMRCUK Research & InnovationASAPBrain Research, UKGovernment of ArgentinaMinistry of Health, SingaporeNBIA Disorders Association
Not available anywhere: 5
Improved neuroprotection using miglustat, curcumin and ibuprofen as a triple combination therapy in Niemann–Pick disease type C1 mice
IM Williams, KL Wallom, DA Smith, N Al Eisa, C Smith, FM Platt
Neurobiology of disease 67, 9-17, 2014
Mandates: UK Medical Research Council
N-butyldeoxygalactonojirimycin reduces brain ganglioside and GM2 content in neonatal Sandhoff disease mice
RC Baek, JL Kasperzyk, FM Platt, TN Seyfried
Neurochemistry international 52 (6), 1125-1133, 2008
Mandates: US National Institutes of Health
Restricted ketogenic diet enhances the therapeutic action of N‐butyldeoxynojirimycin towards brain GM2 accumulation in adult Sandhoff disease mice
CA Denny, KA Heinecke, YP Kim, RC Baek, KS Loh, TD Butters, ...
Journal of neurochemistry 113 (6), 1525-1535, 2010
Mandates: US National Institutes of Health
Measuring relative lysosomal volume for monitoring lysosomal storage diseases
D te Vruchte, KL Wallom, FM Platt
Methods in Cell Biology 126, 331-347, 2015
Mandates: UK Medical Research Council
Divergent Synthesis of Various 2-Aryl Iminocyclitols from (R)-p-Hydroxyphenylglycine
VK Jain
Synthesis 51 (24), 4635-4644, 2019
Mandates: Council of Scientific and Industrial Research, India
Available somewhere: 141
Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease
B Boland, A Kumar, S Lee, FM Platt, J Wegiel, WH Yu, RA Nixon
Journal of Neuroscience 28 (27), 6926-6937, 2008
Mandates: US National Institutes of Health
Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium
E Lloyd-Evans, AJ Morgan, X He, DA Smith, E Elliot-Smith, DJ Sillence, ...
Nature medicine 14 (11), 1247-1255, 2008
Mandates: US National Institutes of Health
Lysosomal storage diseases
FM Platt, A d’Azzo, BL Davidson, EF Neufeld, CJ Tifft
Nature reviews Disease primers 4 (1), 27, 2018
Mandates: US National Institutes of Health, Wellcome Trust, Royal Society UK
Invariant NKT cells reduce the immunosuppressive activity of influenza A virus–induced myeloid-derived suppressor cells in mice and humans
C De Santo, M Salio, SH Masri, LYH Lee, T Dong, AO Speak, S Porubsky, ...
The Journal of clinical investigation 118 (12), 4036-4048, 2008
Mandates: German Research Foundation, Cancer Research UK
A sensitive and specific LC-MS/MS method for rapid diagnosis of Niemann-Pick C1 disease from human plasma [S]
X Jiang, R Sidhu, FD Porter, NM Yanjanin, AO Speak, DT Te Vruchte, ...
Journal of lipid research 52 (7), 1435-1445, 2011
Mandates: US National Institutes of Health
Purified TPC isoforms form NAADP receptors with distinct roles for Ca2+ signaling and endolysosomal trafficking
M Ruas, K Rietdorf, A Arredouani, LC Davis, E Lloyd-Evans, H Koegel, ...
Current biology 20 (8), 703-709, 2010
Mandates: US National Institutes of Health
Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency
S Porubsky, AO Speak, B Luckow, V Cerundolo, FM Platt, HJ Gröne
Proceedings of the National Academy of Sciences 104 (14), 5977-5982, 2007
Mandates: German Research Foundation
Emptying the stores: lysosomal diseases and therapeutic strategies
FM Platt
Nature reviews Drug discovery 17 (2), 133-150, 2018
Mandates: Wellcome Trust, Royal Society UK
NPC1 regulates ER contacts with endocytic organelles to mediate cholesterol egress
D Höglinger, T Burgoyne, E Sanchez-Heras, P Hartwig, A Colaco, ...
Nature communications 10 (1), 4276, 2019
Mandates: US National Institutes of Health, German Research Foundation, UK …
Modulation of human natural killer T cell ligands on TLR-mediated antigen-presenting cell activation
M Salio, AO Speak, D Shepherd, P Polzella, PA Illarionov, N Veerapen, ...
Proceedings of the National Academy of Sciences 104 (51), 20490-20495, 2007
Mandates: Cancer Research UK
High incidence of unrecognized visceral/neurological late-onset Niemann-Pick disease, type C1, predicted by analysis of massively parallel sequencing data sets
CA Wassif, JL Cross, J Iben, L Sanchez-Pulido, A Cougnoux, FM Platt, ...
Genetics in Medicine 18 (1), 41-48, 2016
Mandates: US National Institutes of Health, UK Medical Research Council, Wellcome Trust
RIPK3 as a potential therapeutic target for Gaucher's disease
EB Vitner, R Salomon, T Farfel-Becker, A Meshcheriakova, M Ali, ...
Nature medicine 20 (2), 204-208, 2014
Mandates: UK Medical Research Council
Expression of Ca2+‐permeable two‐pore channels rescues NAADP signalling in TPC‐deficient cells
M Ruas, LC Davis, CC Chen, AJ Morgan, KT Chuang, TF Walseth, ...
The EMBO journal 34 (13), 1743-1758, 2015
Mandates: US National Institutes of Health, German Research Foundation, UK Medical …
Heat shock protein–based therapy as a potential candidate for treating the sphingolipidoses
T Kirkegaard, J Gray, DA Priestman, KL Wallom, J Atkins, OD Olsen, ...
Science translational medicine 8 (355), 355ra118-355ra118, 2016
Mandates: German Research Foundation, Danish Council for Independent Research, Danish …
Vesicular and non-vesicular transport feed distinct glycosylation pathways in the Golgi
G D’Angelo, T Uemura, CC Chuang, E Polishchuk, M Santoro, ...
Nature 501 (7465), 116-120, 2013
Mandates: Fondazione Telethon, Italy, British Heart Foundation, UK Medical Research …
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