Articles with public access mandates - Robert KornelukLearn more
Not available anywhere: 3
TWEAK and cIAP1 regulate myoblast fusion through the noncanonical NF-κB signaling pathway
EK Enwere, J Holbrook, R Lejmi-Mrad, J Vineham, K Timusk, B Sivaraj, ...
Science signaling 5 (246), ra75-ra75, 2012
Mandates: Howard Hughes Medical Institute, Canadian Institutes of Health Research …
Increased X-linked inhibitor of apoptosis protein (XIAP) expression exacerbates experimental autoimmune encephalomyelitis (EAE)
CS Moore, ALO Hebb, MM Blanchard, CE Crocker, P Liston, RG Korneluk, ...
Journal of neuroimmunology 203 (1), 79-93, 2008
Mandates: Genome Canada
The Mammalian IAPs: Multifaceted Inhibitors of Apoptosis
EC LaCasse, HH Cheung, AM Hunter, S Plenchette, DJ Mahoney, ...
Essentials of Apoptosis: A Guide for Basic and Clinical Research, 63-93, 2009
Mandates: Howard Hughes Medical Institute, Canadian Institutes of Health Research
Available somewhere: 28
Noncanonical NF-κB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK
BJ Zarnegar, Y Wang, DJ Mahoney, PW Dempsey, HH Cheung, J He, ...
Nature immunology 9 (12), 1371-1378, 2008
Mandates: US National Institutes of Health, Howard Hughes Medical Institute, Canadian …
IAP-targeted therapies for cancer
EC LaCasse, DJ Mahoney, HH Cheung, S Plenchette, S Baird, ...
Oncogene 27 (48), 6252-6275, 2008
Mandates: Howard Hughes Medical Institute, Canadian Institutes of Health Research
Both cIAP1 and cIAP2 regulate TNFα-mediated NF-κB activation
DJ Mahoney, HH Cheung, RL Mrad, S Plenchette, C Simard, E Enwere, ...
Proceedings of the National Academy of Sciences 105 (33), 11778-11783, 2008
Mandates: Howard Hughes Medical Institute, Canadian Institutes of Health Research
Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2
MJM Bertrand, K Doiron, K Labbé, RG Korneluk, PA Barker, M Saleh
Immunity 30 (6), 789-801, 2009
Mandates: Canadian Institutes of Health Research, Fonds de recherche du Québec - Santé
cIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation
S McComb, HH Cheung, RG Korneluk, S Wang, L Krishnan, S Sad
Cell Death & Differentiation 19 (11), 1791-1801, 2012
Mandates: Canadian Institutes of Health Research, Ontario Institute for Cancer Research
Modulation of immune signalling by inhibitors of apoptosis
ST Beug, HH Cheung, EC LaCasse, RG Korneluk
Trends in immunology 33 (11), 535-545, 2012
Mandates: Howard Hughes Medical Institute, Canadian Institutes of Health Research …
Smac mimetics and innate immune stimuli synergize to promote tumor death
ST Beug, VA Tang, EC LaCasse, HH Cheung, CE Beauregard, J Brun, ...
Nature biotechnology 32 (2), 182-190, 2014
Mandates: Canadian Cancer Society, Canadian Institutes of Health Research
Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma
ST Beug, CE Beauregard, C Healy, T Sanda, M St-Jean, J Chabot, ...
Nature Communications 8 (1), 14278, 2017
Mandates: Canadian Cancer Society, Canadian Institutes of Health Research
Down-regulation of c-FLIP Enhances death of cancer cells by smac mimetic compound
HH Cheung, DJ Mahoney, EC LaCasse, RG Korneluk
Cancer research 69 (19), 7729-7738, 2009
Mandates: Howard Hughes Medical Institute, Canadian Institutes of Health Research
The RING domain of cIAP1 mediates the degradation of RING-bearing inhibitor of apoptosis proteins by distinct pathways
HH Cheung, S Plenchette, CJ Kern, DJ Mahoney, RG Korneluk
Molecular biology of the cell 19 (7), 2729-2740, 2008
Mandates: Howard Hughes Medical Institute, Canadian Institutes of Health Research
Role of the TWEAK-Fn14-cIAP1-NF-κB signaling axis in the regulation of myogenesis and muscle homeostasis
EK Enwere, EC LaCasse, NJ Adam, RG Korneluk
Frontiers in immunology 5, 34, 2014
Mandates: Canadian Institutes of Health Research
Restoration of XAF1 expression induces apoptosis and inhibits tumor growth in gastric cancer
SP Tu, P Liston, JT Cui, MCM Lin, XH Jiang, Y Yang, Q Gu, SH Jiang, ...
International journal of cancer 125 (3), 688-697, 2009
Mandates: Canadian Institutes of Health Research
IGF2BP1 controls cell death and drug resistance in rhabdomyosarcomas by regulating translation of cIAP1
MD Faye, ST Beug, TE Graber, N Earl, X Xiang, B Wild, S Langlois, ...
Oncogene 34 (12), 1532-1541, 2015
Mandates: Canadian Institutes of Health Research
Over-expression of X-linked inhibitor of apoptosis protein slows presbycusis in C57BL/6J mice
J Wang, T Menchenton, S Yin, Z Yu, M Bance, DP Morris, CS Moore, ...
Neurobiology of aging 31 (7), 1238-1249, 2010
Mandates: Canadian Institutes of Health Research
Inhibitor of apoptosis proteins, NAIP, cIAP1 and cIAP2 expression during macrophage differentiation and M1/M2 polarization
V Morón-Calvente, S Romero-Pinedo, S Toribio-Castelló, J Plaza-Díaz, ...
PLoS One 13 (3), e0193643, 2018
Mandates: Canadian Institutes of Health Research
SMG1 and NIK regulate apoptosis induced by Smac mimetic compounds
HH Cheung, M St Jean, ST Beug, R Lejmi-Mrad, E LaCasse, SD Baird, ...
Cell death & disease 2 (4), e146-e146, 2011
Mandates: Howard Hughes Medical Institute, Canadian Institutes of Health Research …
Smac mimetic compounds potentiate interleukin-1β-mediated cell death
HH Cheung, ST Beug, MS Jean, A Brewster, NL Kelly, S Wang, ...
Journal of Biological Chemistry 285 (52), 40612-40623, 2010
Mandates: Howard Hughes Medical Institute, Canadian Institutes of Health Research …
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