Artemisinin and the antimalarial endoperoxides: from herbal remedy to targeted chemotherapy SR Meshnick, TE Taylor, S Kamchonwongpaisan Microbiological reviews 60 (2), 301-315, 1996 | 980 | 1996 |
Insights into antifolate resistance from malarial DHFR-TS structures J Yuvaniyama, P Chitnumsub, S Kamchonwongpaisan, J Vanichtanankul, ... Nature Structural & Molecular Biology 10 (5), 357-365, 2003 | 485 | 2003 |
Iron-dependent free radical generation from the antimalarial agent artemisinin (qinghaosu) SR Meshnick, YZ Yang, V Lima, F Kuypers, S Kamchonwongpaisan, ... Antimicrobial agents and chemotherapy 37 (5), 1108-1114, 1993 | 430 | 1993 |
Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target Y Yuthavong, B Tarnchompoo, T Vilaivan, P Chitnumsub, ... Proceedings of the National Academy of Sciences 109 (42), 16823-16828, 2012 | 294 | 2012 |
Stepwise acquisition of pyrimethamine resistance in the malaria parasite ER Lozovsky, T Chookajorn, KM Brown, M Imwong, PJ Shaw, ... Proceedings of the National Academy of Sciences 106 (29), 12025-12030, 2009 | 291 | 2009 |
Inducible Knockdown of Plasmodium Gene Expression Using the glmS Ribozyme P Prommana, C Uthaipibull, C Wongsombat, S Kamchonwongpaisan, ... PloS one 8 (8), e73783, 2013 | 263 | 2013 |
Interaction of pyrimethamine, cycloguanil, WR99210 and their analogues with Plasmodium falciparum dihydrofolate reductase: structural basis of antifolate resistance G Rastelli, W Sirawaraporn, P Sompornpisut, T Vilaivan, ... Bioorganic & medicinal chemistry 8 (5), 1117-1128, 2000 | 157 | 2000 |
Inhibitors of Multiple Mutants of Plasmodium falciparum Dihydrofolate Reductase and Their Antimalarial Activities S Kamchonwongpaisan, R Quarrell, N Charoensetakul, R Ponsinet, ... Journal of Medicinal Chemistry 47 (3), 673-680, 2004 | 141 | 2004 |
A Genetically Hard-Wired Metabolic Transcriptome in Plasmodium falciparum Fails to Mount Protective Responses to Lethal Antifolates K Ganesan, N Ponmee, L Jiang, JW Fowble, J White, ... PLoS pathogens 4 (11), e1000214, 2008 | 138 | 2008 |
Malarial (Plasmodium falciparum) dihydrofolate reductase-thymidylate synthase: structural basis for antifolate resistance and development of effective inhibitors Y Yuthavong, J Yuvaniyama, P Chitnumsub, J Vanichtanankul, ... Parasitology 130 (3), 249-259, 2005 | 128 | 2005 |
Artemisinin neurotoxicity: neuropathology in rats and mechanistic studies in vitro. S Kamchonwongpaisan, P McKeever, P Hossler, H Ziffer, SR Meshnick The American journal of tropical medicine and hygiene 56 (1), 7-12, 1997 | 126 | 1997 |
Carbonic anhydrase inhibitors. Inhibition of Plasmodium falciparum carbonic anhydrase with aromatic sulfonamides: towards antimalarials with a novel mechanism of action? J Krungkrai, A Scozzafava, S Reungprapavut, SR Krungkrai, R Rattanajak, ... Bioorganic & medicinal chemistry 13 (2), 483-489, 2005 | 122 | 2005 |
Antimycobacterial and antiplasmodial cyclodepsipeptides from the insect pathogenic fungus Paecilomyces tenuipes BCC 1614 C Nilanonta, M Isaka, P Kittakoop, P Palittapongarnpim, ... Planta medica 66 (08), 756-758, 2000 | 121 | 2000 |
The mode of action of the antimalarial artemisinin and its derivatives S Kamchonwongpaisan, SR Meshnick General Pharmacology: The Vascular System 27 (4), 587-592, 1996 | 120 | 1996 |
Evaluation of an ethnopharmacologically selected Bhutanese medicinal plants for their major classes of phytochemicals and biological activities P Wangchuk, PA Keller, SG Pyne, M Taweechotipatr, A Tonsomboon, ... Journal of Ethnopharmacology 137 (1), 730-742, 2011 | 119 | 2011 |
Development of 2, 4-Diaminopyrimidines as Antimalarials Based on Inhibition of the S108N and C59R+ S108N Mutants of Dihydrofolate Reductase from Pyrimethamine-Resistant … B Tarnchompoo, C Sirichaiwat, W Phupong, C Intaraudom, ... Journal of Medicinal Chemistry 45 (6), 1244-1252, 2002 | 118 | 2002 |
Target guided synthesis of 5-benzyl-2, 4-diamonopyrimidines: their antimalarial activities and binding affinities to wild type and mutant dihydrofolate reductases from … C Sirichaiwat, C Intaraudom, S Kamchonwongpaisan, J Vanichtanankul, ... Journal of medicinal chemistry 47 (2), 345-354, 2004 | 114 | 2004 |
C-16 artemisinin derivatives and their antimalarial and cytotoxic activities: syntheses of artemisinin monomers, dimers, trimers, and tetramers by nucleophilic additions to … S Ekthawatchai, S Kamchonwongpaisan, P Kongsaeree, B Tarnchompoo, ... Journal of medicinal chemistry 44 (26), 4688-4695, 2001 | 98 | 2001 |
An antimalarial peroxide from Amomum krervanh Pierre S Kamchonwongpaisan, C Nilanonta, B Tarnchompoo, C Thebtaranonth, ... Tetrahedron letters 36 (11), 1821-1824, 1995 | 84 | 1995 |
Development of a Lead Inhibitor for the A16V+S108T Mutant of Dihydrofolate Reductase from the Cycloguanil-Resistant Strain (T9/94) of Plasmodium falciparum† Y Yuthavong, T Vilaivan, N Chareonsethakul, S Kamchonwongpaisan, ... Journal of medicinal chemistry 43 (14), 2738-2744, 2000 | 78 | 2000 |