| Histone acetylation by Trrap–Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks R Murr, JI Loizou, YG Yang, C Cuenin, H Li, ZQ Wang, Z Herceg Nature cell biology 8 (1), 91-99, 2006 | 705 | 2006 |
| Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy KVM Huber, E Salah, B Radic, M Gridling, JM Elkins, A Stukalov, ... Nature 508 (7495), 222-227, 2014 | 445 | 2014 |
| The protein kinase CK2 facilitates repair of chromosomal DNA single-strand breaks JI Loizou, SF El-Khamisy, A Zlatanou, DJ Moore, DW Chan, J Qin, ... Cell 117 (1), 17-28, 2004 | 380 | 2004 |
| DNA replication stress: causes, resolution and disease A Mazouzi, G Velimezi, JI Loizou Experimental cell research 329 (1), 85-93, 2014 | 271 | 2014 |
| Interference of papillomavirus E6 protein with single-strand break repair by interaction with XRCC1 T Iftner, M Elbel, B Schopp, T Hiller, JI Loizou, KW Caldecott, ... The EMBO journal 21 (17), 4741-4748, 2002 | 205 | 2002 |
| Validating the concept of mutational signatures with isogenic cell models X Zou, M Owusu, R Harris, SP Jackson, JI Loizou, S Nik-Zainal Nature communications 9 (1), 1744, 2018 | 158 | 2018 |
| Prime editing efficiency and fidelity are enhanced in the absence of mismatch repair J Ferreira da Silva, GP Oliveira, EA Arasa-Verge, C Kagiou, A Moretton, ... Nature communications 13 (1), 760, 2022 | 123 | 2022 |
| Targeting the DNA repair enzyme polymerase θ in cancer therapy A Schrempf, J Slyskova, JI Loizou Trends in cancer 7 (2), 98-111, 2021 | 119 | 2021 |
| Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis NK Serwas, B Hoeger, RC Ardy, SV Stulz, Z Sui, N Memaran, M Meeths, ... Nature Communications 10 (1), 3106, 2019 | 71 | 2019 |
| Epigenetic information in chromatin: the code of entry for DNA repair JI Loizou, R Murr, MG Finkbeiner, C Sawan, ZQ Wang, Z Herceg Cell Cycle 5 (7), 696-701, 2006 | 70 | 2006 |
| CDK6 antagonizes p53-induced responses during tumorigenesis F Bellutti, AS Tigan, S Nebenfuehr, M Dolezal, M Zojer, R Grausenburger, ... Cancer discovery 8 (7), 884-897, 2018 | 67 | 2018 |
| Interplay between cellular metabolism and the DNA damage response in cancer A Moretton, JI Loizou Cancers 12 (8), 2051, 2020 | 62 | 2020 |
| Klebsiella oxytoca enterotoxins tilimycin and tilivalline have distinct host DNA-damaging and microtubule-stabilizing activities K Unterhauser, L Pöltl, G Schneditz, S Kienesberger, RA Glabonjat, ... Proceedings of the National Academy of Sciences 116 (9), 3774-3783, 2019 | 59 | 2019 |
| Polymerase δ deficiency causes syndromic immunodeficiency with replicative stress CD Conde, ÖY Petronczki, S Baris, KL Willmann, E Girardi, E Salzer, ... The Journal of clinical investigation 129 (10), 4194-4206, 2019 | 50 | 2019 |
| Competition between NBS1 and ATMIN controls ATM signaling pathway choice T Zhang, K Penicud, C Bruhn, JI Loizou, N Kanu, ZQ Wang, A Behrens Cell reports 2 (6), 1498-1504, 2012 | 48 | 2012 |
| High activation of STAT5A drives peripheral T-cell lymphoma and leukemia B Maurer, H Nivarthi, B Wingelhofer, HTT Pham, M Schlederer, T Suske, ... Haematologica 105 (2), 435, 2020 | 47 | 2020 |
| POLθ prevents MRE11-NBS1-CtIP-dependent fork breakage in the absence of BRCA2/RAD51 by filling lagging-strand gaps A Mann, MA Ramirez-Otero, A De Antoni, YW Hanthi, V Sannino, G Baldi, ... Molecular Cell 82 (22), 4218-4231. e8, 2022 | 46 | 2022 |
| Repair of UV-induced DNA damage independent of nucleotide excision repair is masked by MUTYH A Mazouzi, F Battistini, SC Moser, JF da Silva, M Wiedner, M Owusu, ... Molecular cell 68 (4), 797-807. e7, 2017 | 46 | 2017 |
| ATMIN is required for maintenance of genomic stability and suppression of B cell lymphoma JI Loizou, R Sancho, N Kanu, DJ Bolland, F Yang, C Rada, AE Corcoran, ... Cancer cell 19 (5), 587-600, 2011 | 41 | 2011 |
| Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48 G Velimezi, L Robinson-Garcia, F Muñoz-Martínez, WW Wiegant, ... Nature communications 9 (1), 2280, 2018 | 40 | 2018 |
