Articles with public access mandates - Joanna LoizouLearn more
Available somewhere: 40
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy
KVM Huber, E Salah, B Radic, M Gridling, JM Elkins, A Stukalov, ...
Nature 508 (7495), 222-227, 2014
Mandates: Austrian Science Fund, Canadian Institutes of Health Research, Genome Canada …
DNA replication stress: causes, resolution and disease
A Mazouzi, G Velimezi, JI Loizou
Experimental cell research 329 (1), 85-93, 2014
Mandates: Austrian Science Fund
Validating the concept of mutational signatures with isogenic cell models
X Zou, M Owusu, R Harris, SP Jackson, JI Loizou, S Nik-Zainal
Nature communications 9 (1), 1744, 2018
Mandates: Austrian Science Fund, Cancer Research UK, Wellcome Trust
Prime editing efficiency and fidelity are enhanced in the absence of mismatch repair
J Ferreira da Silva, GP Oliveira, EA Arasa-Verge, C Kagiou, A Moretton, ...
Nature communications 13 (1), 760, 2022
Mandates: Austrian Science Fund, European Commission
Targeting the DNA repair enzyme polymerase θ in cancer therapy
A Schrempf, J Slyskova, JI Loizou
Trends in cancer 7 (2), 98-111, 2021
Mandates: European Commission
Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis
NK Serwas, B Hoeger, RC Ardy, SV Stulz, Z Sui, N Memaran, M Meeths, ...
Nature Communications 10 (1), 3106, 2019
Mandates: US National Institutes of Health, Austrian Science Fund, Knut and Alice …
CDK6 antagonizes p53-induced responses during tumorigenesis
F Bellutti, AS Tigan, S Nebenfuehr, M Dolezal, M Zojer, R Grausenburger, ...
Cancer discovery 8 (7), 884-897, 2018
Mandates: Austrian Science Fund, European Commission
Interplay between cellular metabolism and the DNA damage response in cancer
A Moretton, JI Loizou
Cancers 12 (8), 2051, 2020
Mandates: Austrian Science Fund
Klebsiella oxytoca enterotoxins tilimycin and tilivalline have distinct host DNA-damaging and microtubule-stabilizing activities
K Unterhauser, L Pöltl, G Schneditz, S Kienesberger, RA Glabonjat, ...
Proceedings of the National Academy of Sciences 116 (9), 3774-3783, 2019
Mandates: Austrian Science Fund
Polymerase δ deficiency causes syndromic immunodeficiency with replicative stress
CD Conde, ÖY Petronczki, S Baris, KL Willmann, E Girardi, E Salzer, ...
The Journal of clinical investigation 129 (10), 4194-4206, 2019
Mandates: Austrian Science Fund, European Commission
Competition between NBS1 and ATMIN controls ATM signaling pathway choice
T Zhang, K Penicud, C Bruhn, JI Loizou, N Kanu, ZQ Wang, A Behrens
Cell reports 2 (6), 1498-1504, 2012
Mandates: Cancer Research UK
POLθ prevents MRE11-NBS1-CtIP-dependent fork breakage in the absence of BRCA2/RAD51 by filling lagging-strand gaps
A Mann, MA Ramirez-Otero, A De Antoni, YW Hanthi, V Sannino, G Baldi, ...
Molecular Cell 82 (22), 4218-4231. e8, 2022
Mandates: Austrian Science Fund, European Commission, AIRC Foundation for Cancer …
High activation of STAT5A drives peripheral T-cell lymphoma and leukemia
B Maurer, H Nivarthi, B Wingelhofer, HTT Pham, M Schlederer, T Suske, ...
Haematologica 105 (2), 435, 2020
Mandates: Austrian Science Fund
Repair of UV-induced DNA damage independent of nucleotide excision repair is masked by MUTYH
A Mazouzi, F Battistini, SC Moser, JF da Silva, M Wiedner, M Owusu, ...
Molecular cell 68 (4), 797-807. e7, 2017
Mandates: Austrian Science Fund, European Commission, Government of Spain
POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells
A Schrempf, S Bernardo, EAA Verge, MAR Otero, J Wilson, D Kirchhofer, ...
Cell reports 41 (9), 2022
Mandates: Austrian Science Fund, European Commission, AIRC Foundation for Cancer …
ATMIN is required for maintenance of genomic stability and suppression of B cell lymphoma
JI Loizou, R Sancho, N Kanu, DJ Bolland, F Yang, C Rada, AE Corcoran, ...
Cancer cell 19 (5), 587-600, 2011
Mandates: Cancer Research UK
Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48
G Velimezi, L Robinson-Garcia, F Muñoz-Martínez, WW Wiegant, ...
Nature communications 9 (1), 2280, 2018
Mandates: US National Institutes of Health, Austrian Science Fund, Cancer Research UK …
MEK inhibitors block growth of lung tumours with mutations in ataxia–telangiectasia mutated
M Smida, F Fece de La Cruz, C Kerzendorfer, IZ Uras, B Mair, A Mazouzi, ...
Nature communications 7 (1), 13701, 2016
Mandates: Austrian Science Fund, European Commission, Vienna Science and Technology …
Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia
M Moder, G Velimezi, M Owusu, A Mazouzi, M Wiedner, ...
Nature communications 8 (1), 1238, 2017
Mandates: US National Institutes of Health, Austrian Science Fund, Cancer Research UK
ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress
L Schmidt, M Wiedner, G Velimezi, J Prochazkova, M Owusu, S Bauer, ...
DNA repair 24, 122-130, 2014
Mandates: Austrian Science Fund
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