Increased trabecular bone and improved biomechanics in an osteocalcin-null rat model created by CRISPR/Cas9 technology LJ Lambert, AK Challa, A Niu, L Zhou, J Tucholski, MS Johnson, TR Nagy, ... Disease models & mechanisms 9 (10), 1169-1179, 2016 | 89 | 2016 |
Identification and characterization of roundabout orthologs in zebrafish AK Challa, CE Beattie, MA Seeger Mechanisms of development 101 (1-2), 249-253, 2001 | 69 | 2001 |
Enhanced Keap1-Nrf2 signaling protects the myocardium from isoproterenol-induced pathological remodeling in mice G Shanmugam, AK Challa, SH Litovsky, A Devarajan, D Wang, DP Jones, ... Redox biology 27, 101212, 2019 | 66 | 2019 |
Caffeine-induced effects on heart rate in zebrafish embryos and possible mechanisms of action: an effective system for experiments in chemical biology N Rana, M Moond, A Marthi, S Bapatla, T Sarvepalli, K Chatti, AK Challa Zebrafish 7 (1), 69-81, 2010 | 62 | 2010 |
NF1 deficiency correlates with estrogen receptor signaling and diminished survival in breast cancer PS Dischinger, EA Tovar, CJ Essenburg, ZB Madaj, EE Gardner, ... NPJ breast cancer 4 (1), 29, 2018 | 47 | 2018 |
Mutation of growth arrest specific 8 reveals a role in motile cilia function and human disease WR Lewis, EB Malarkey, D Tritschler, R Bower, RC Pasek, JD Porath, ... PLoS genetics 12 (7), e1006220, 2016 | 39 | 2016 |
First year course-based undergraduate research experience (CURE) using the CRISPR/Cas9 genome engineering technology in zebrafish JM Bhatt, AK Challa Journal of microbiology & biology education 19 (1), 10.1128/jmbe. v19i1. 1245, 2018 | 38 | 2018 |
9-O-Acetylation of exogenously added ganglioside GD3: the GD3 molecule induces its own O-acetylation machinery HY Chen, AK Challa, A Varki Journal of Biological Chemistry 281 (12), 7825-7833, 2006 | 30 | 2006 |
Robo3 isoforms have distinct roles during zebrafish development AK Challa, ML McWhorter, C Wang, MA Seeger, CE Beattie Mechanisms of development 122 (10), 1073-1086, 2005 | 29 | 2005 |
Exercise mediated Nrf2 signaling protects the myocardium from isoproterenol-induced pathological remodeling G Shanmugam, AK Challa, A Devarajan, B Athmanathan, SH Litovsky, ... Frontiers in cardiovascular medicine 6, 68, 2019 | 28 | 2019 |
Heterozygous Pkhd1C642* mice develop cystic liver disease and proximal tubule ectasia that mimics radiographic signs of medullary sponge kidney D Shan, G Rezonzew, S Mullen, R Roye, J Zhou, P Chumley, DZ Revell, ... American Journal of Physiology-Renal Physiology 316 (3), F463-F472, 2019 | 27 | 2019 |
Novel Hypomorphic Alleles of the Mouse Tyrosinase Gene Induced by CRISPR-Cas9 Nucleases Cause Non-Albino Pigmentation Phenotypes AK Challa, ER Boitet, AN Turner, LW Johnson, D Kennedy, ER Downs, ... PLoS ONE 11 (5), e0155812, 2016 | 24 | 2016 |
A mixing heteroduplex mobility assay (mHMA) to genotype homozygous mutants with small indels generated by CRISPR-Cas9 nucleases SD Foster, SR Glover, AN Turner, K Chatti, AK Challa MethodsX 6, 1, 2019 | 22 | 2019 |
Conservation and early expression of zebrafish tyrosine kinases support the utility of zebrafish as a model for tyrosine kinase biology AK Challa, K Chatti Zebrafish 10 (3), 264-274, 2013 | 22 | 2013 |
Training in scientific manuscript writing RH Glew, AK Challa, V Gopalan Current Science, 1386-1392, 2014 | 19 | 2014 |
Truncating PKHD1 and PKD2 mutations alter energy metabolism P Chumley, J Zhou, S Mrug, B Chacko, JM Parant, AK Challa, LS Wilson, ... American journal of physiology-renal physiology 316 (3), F414-F425, 2019 | 18 | 2019 |
Student perceptions of authoring a publication stemming from a course-based undergraduate research experience (CURE) AN Turner, AK Challa, KM Cooper CBE—Life Sciences Education 20 (3), ar46, 2021 | 17 | 2021 |
Identification of Nrf2-responsive microRNA networks as putative mediators of myocardial reductive stress JM Quiles, ME Pepin, S Sunny, SB Shelar, AK Challa, B Dalley, JR Hoidal, ... Scientific Reports 11 (1), 11977, 2021 | 16 | 2021 |
Physiological and metabolic features of mice with CRISPR/Cas9-mediated loss-of-function in growth hormone-releasing hormone M Icyuz, M Fitch, F Zhang, A Challa, LY Sun Aging (Albany NY) 12 (10), 9761, 2020 | 16 | 2020 |
PHLPP1 promotes neutral lipid accumulation through AMPK/ChREBP-dependent lipid uptake and fatty acid synthesis pathways K Balamurugan, R Medishetti, J Kotha, P Behera, K Chandra, ... Iscience 25 (2), 2022 | 14 | 2022 |