| High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells Y Fu, JA Foden, C Khayter, ML Maeder, D Reyon, JK Joung, JD Sander Nature biotechnology 31 (9), 822-826, 2013 | 3953 | 2013 |
| Efficient genome editing in zebrafish using a CRISPR-Cas system WY Hwang, Y Fu, D Reyon, ML Maeder, SQ Tsai, JD Sander, ... Nature biotechnology 31 (3), 227-229, 2013 | 3775 | 2013 |
| Improving CRISPR-Cas nuclease specificity using truncated guide RNAs Y Fu, JD Sander, D Reyon, VM Cascio, JK Joung Nature biotechnology 32 (3), 279-284, 2014 | 2529 | 2014 |
| CRISPR RNA–guided activation of endogenous human genes ML Maeder, SJ Linder, VM Cascio, Y Fu, QH Ho, JK Joung Nature methods 10 (10), 977-979, 2013 | 1538 | 2013 |
| Heritable and precise zebrafish genome editing using a CRISPR-Cas system WY Hwang, Y Fu, D Reyon, ML Maeder, P Kaini, JD Sander, JK Joung, ... PloS one 8 (7), e68708, 2013 | 502 | 2013 |
| Robust, synergistic regulation of human gene expression using TALE activators ML Maeder, SJ Linder, D Reyon, JF Angstman, Y Fu, JD Sander, ... Nature methods 10 (3), 243-245, 2013 | 303 | 2013 |
| Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editing JK Joung, JD Sander, M Maeder, Y Fu US Patent 9,567,604, 2017 | 286 | 2017 |
| Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editing JK Joung, JD Sander, Y Fu, M Maeder US Patent 10,119,133, 2018 | 171 | 2018 |
| Mir-144 selectively regulates embryonic α-hemoglobin synthesis during primitive erythropoiesis YF Fu, TT Du, M Dong, KY Zhu, CB Jing, Y Zhang, L Wang, HB Fan, ... Blood, The Journal of the American Society of Hematology 113 (6), 1340-1349, 2009 | 155 | 2009 |
| Efficient in vivo genome editing using RNA-guided nucleases WY Hwang, Y Fu, D Reyon, ML Maeder, SQ Tsai, JD Sander, ... Nature biotechnology 31 (3), 227, 2013 | 127 | 2013 |
| In vivo interstitial migration of primitive macrophages mediated by JNK-matrix metalloproteinase 13 signaling in response to acute injury Y Zhang, XT Bai, KY Zhu, Y Jin, M Deng, HY Le, YF Fu, Y Chen, J Zhu, ... The Journal of Immunology 181 (3), 2155-2164, 2008 | 119 | 2008 |
| CAUSEL: an epigenome-and genome-editing pipeline for establishing function of noncoding GWAS variants S Spisák, K Lawrenson, Y Fu, I Csabai, RT Cottman, JH Seo, C Haiman, ... Nature medicine 21 (11), 1357-1363, 2015 | 110 | 2015 |
| Efficient CRISPR/Cas9-mediated editing of trinucleotide repeat expansion in myotonic dystrophy patient-derived iPS and myogenic cells S Dastidar, S Ardui, K Singh, D Majumdar, N Nair, Y Fu, D Reyon, ... Nucleic acids research 46 (16), 8275-8298, 2018 | 89 | 2018 |
| Targeted genome editing in human cells using CRISPR/Cas nucleases and truncated guide RNAs Y Fu, D Reyon, JK Joung Methods in enzymology 546, 21-45, 2014 | 87 | 2014 |
| Heritable and lineage-specific gene knockdown in zebrafish embryo M Dong, YF Fu, TT Du, CB Jing, CT Fu, Y Chen, Y Jin, M Deng, TX Liu PLoS One 4 (7), e6125, 2009 | 64 | 2009 |
| Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editing JK Joung, JD Sander, M Maeder, Y Fu US Patent 10,415,059, 2019 | 47 | 2019 |
| An evolutionarily conserved PTEN-C/EBPα-CTNNA1 axis controls myeloid development and transformation CT Fu, KY Zhu, JQ Mi, YF Liu, ST Murray, YF Fu, CG Ren, ZW Dong, ... Blood, The Journal of the American Society of Hematology 115 (23), 4715-4724, 2010 | 46 | 2010 |
| Experimental validation and complexity of miRNA–mRNA target interaction during zebrafish primitive erythropoiesis TT Du, YF Fu, M Dong, L Wang, HB Fan, Y Chen, Y Jin, SJ Chen, Z Chen, ... Biochemical and biophysical research communications 381 (4), 688-693, 2009 | 32 | 2009 |
| Functional characterization of lmo2‐Cre transgenic zebrafish L Wang, Y Zhang, T Zhou, YF Fu, TT Du, Y Jin, Y Chen, CG Ren, XL Peng, ... Developmental Dynamics: An Official Publication of the American Association …, 2008 | 32 | 2008 |
| Targeted mutagenesis in zebrafish using CRISPR RNA-guided nucleases WY Hwang, Y Fu, D Reyon, APW Gonzales, JK Joung, JRJ Yeh CRISPR: Methods and protocols, 317-334, 2015 | 30 | 2015 |