Integrins and signal transduction pathways: the road taken EA Clark, JS Brugge Science 268 (5208), 233-239, 1995 | 3970 | 1995 |
Cellular functions regulated by Src family kinases SM Thomas, JS Brugge Annual review of cell and developmental biology 13 (1), 513-609, 1997 | 3208 | 1997 |
Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures J Debnath, SK Muthuswamy, JS Brugge Methods 30 (3), 256-268, 2003 | 2362 | 2003 |
Modelling glandular epithelial cancers in three-dimensional cultures J Debnath, JS Brugge Nature Reviews Cancer 5 (9), 675-688, 2005 | 1273 | 2005 |
Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases M Rozakis-Adcock, J McGlade, G Mbamalu, G Pelicci, R Daly, W Li, ... Nature 360 (6405), 689-692, 1992 | 1240 | 1992 |
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis JW Locasale, AR Grassian, T Melman, CA Lyssiotis, KR Mattaini, AJ Bass, ... Nature genetics 43 (9), 869-874, 2011 | 1194 | 2011 |
Identification of a transformation-specific antigen induced by an avian sarcoma virus JS Brugge, RL Erikson Nature 269 (5626), 346-348, 1977 | 1153 | 1977 |
A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen XJ Ma, Z Wang, PD Ryan, SJ Isakoff, A Barmettler, A Fuller, B Muir, ... Cancer cell 5 (6), 607-616, 2004 | 1136 | 2004 |
Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment ZT Schafer, AR Grassian, L Song, Z Jiang, Z Gerhart-Hines, HY Irie, ... Nature 461 (7260), 109-113, 2009 | 1126 | 2009 |
Sensing the environment: a historical perspective on integrin signal transduction CK Miranti, JS Brugge Nature cell biology 4 (4), E83-E90, 2002 | 1125 | 2002 |
Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon M Overholtzer, J Zhang, GA Smolen, B Muir, W Li, DC Sgroi, CX Deng, ... Proceedings of the National Academy of Sciences 103 (33), 12405-12410, 2006 | 1064 | 2006 |
Signal transduction in cancer R Sever, JS Brugge Cold Spring Harbor perspectives in medicine 5 (4), a006098, 2015 | 1031 | 2015 |
Engineering tumors with 3D scaffolds C Fischbach, R Chen, T Matsumoto, T Schmelzle, JS Brugge, PJ Polverini, ... Nature methods 4 (10), 855-860, 2007 | 1022 | 2007 |
The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini J Debnath, KR Mills, NL Collins, MJ Reginato, SK Muthuswamy, ... Cell 111 (1), 29-40, 2002 | 955 | 2002 |
Mutant p53 drives invasion by promoting integrin recycling PAJ Muller, PT Caswell, B Doyle, MP Iwanicki, EH Tan, S Karim, ... Cell 139 (7), 1327-1341, 2009 | 901 | 2009 |
Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets. L Lipfert, B Haimovich, MD Schaller, BS Cobb, JT Parsons, JS Brugge The Journal of cell biology 119 (4), 905-912, 1992 | 840 | 1992 |
Ras is essential for nerve growth factor-and phorbol ester-induced tyrosine phosphorylation of MAP kinases SM Thomas, M DeMarco, G D'Arcangelo, S Halegoua, JS Brugge Cell 68 (6), 1031-1040, 1992 | 839 | 1992 |
A nonapoptotic cell death process, entosis, that occurs by cell-in-cell invasion M Overholtzer, AA Mailleux, G Mouneimne, G Normand, SJ Schnitt, ... Cell 131 (5), 966-979, 2007 | 818 | 2007 |
Integrin-mediated signals regulated by members of the rho family of GTPases EA Clark, WG King, JS Brugge, M Symons, RO Hynes The Journal of cell biology 142 (2), 573-586, 1998 | 815 | 1998 |
Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation D Mukhopadhyay, L Tsiokas, XM Zhou, D Foster, JS Brugge, ... Nature 375 (6532), 577-581, 1995 | 744 | 1995 |