Articles with public access mandates - JOAN BRUGGELearn more
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Nano-pelargonidin protects hyperglycemic-induced L6 cells against mitochondrial dysfunction
A Samadder, D Tarafdar, SK Abraham, K Ghosh, AR Khuda-Bukhsh
Planta Medica 83 (05), 468-475, 2017
Mandates: Council of Scientific and Industrial Research, India
Available somewhere: 82
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
JW Locasale, AR Grassian, T Melman, CA Lyssiotis, KR Mattaini, AJ Bass, ...
Nature genetics 43 (9), 869-874, 2011
Mandates: US National Institutes of Health
Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
ZT Schafer, AR Grassian, L Song, Z Jiang, Z Gerhart-Hines, HY Irie, ...
Nature 461 (7260), 109-113, 2009
Mandates: US National Institutes of Health
Engineering tumors with 3D scaffolds
C Fischbach, R Chen, T Matsumoto, T Schmelzle, JS Brugge, PJ Polverini, ...
Nature methods 4 (10), 855-860, 2007
Mandates: German Research Foundation
Mutant p53 drives invasion by promoting integrin recycling
PAJ Muller, PT Caswell, B Doyle, MP Iwanicki, EH Tan, S Karim, ...
Cell 139 (7), 1327-1341, 2009
Mandates: US National Institutes of Health, Cancer Research UK
Frequency-modulated pulses of ERK activity transmit quantitative proliferation signals
JG Albeck, GB Mills, JS Brugge
Molecular cell 49 (2), 249-261, 2013
Mandates: US National Institutes of Health
Identification of genes that regulate epithelial cell migration using an siRNA screening approach
KJ Simpson, LM Selfors, J Bui, A Reynolds, D Leake, A Khvorova, ...
Nature cell biology 10 (9), 1027-1038, 2008
Mandates: US National Institutes of Health
YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway
J Zhang, JY Ji, M Yu, M Overholtzer, GA Smolen, R Wang, JS Brugge, ...
Nature cell biology 11 (12), 1444-1450, 2009
Mandates: US National Institutes of Health, Howard Hughes Medical Institute
Oncogene-like induction of cellular invasion from centrosome amplification
SA Godinho, R Picone, M Burute, R Dagher, Y Su, CT Leung, K Polyak, ...
Nature 510 (7503), 167-171, 2014
Mandates: US National Institutes of Health, Howard Hughes Medical Institute, Fundação …
Inhibition of PI3K/mTOR leads to adaptive resistance in matrix-attached cancer cells
T Muranen, LM Selfors, DT Worster, MP Iwanicki, L Song, FC Morales, ...
Cancer cell 21 (2), 227-239, 2012
Mandates: US National Institutes of Health
Substrate stiffness regulates cadherin-dependent collective migration through myosin-II contractility
MR Ng, A Besser, G Danuser, JS Brugge
Journal of Cell Biology 199 (3), 545-563, 2012
Mandates: US National Institutes of Health, German Research Foundation
Ovarian cancer spheroids use myosin-generated force to clear the mesothelium
MP Iwanicki, RA Davidowitz, MR Ng, A Besser, T Muranen, M Merritt, ...
Cancer discovery 1 (2), 144-157, 2011
Mandates: US National Institutes of Health, German Research Foundation
Cycling cancer persister cells arise from lineages with distinct programs
Y Oren, M Tsabar, MS Cuoco, L Amir-Zilberstein, HF Cabanos, JC Hütter, ...
Nature 596 (7873), 576-582, 2021
Mandates: US National Institutes of Health, Howard Hughes Medical Institute, V …
Differential glutamate metabolism in proliferating and quiescent mammary epithelial cells
JL Coloff, JP Murphy, CR Braun, IS Harris, LM Shelton, K Kami, SP Gygi, ...
Cell metabolism 23 (5), 867-880, 2016
Mandates: US National Institutes of Health
Outgrowth of single oncogene-expressing cells from suppressive epithelial environments
CT Leung, JS Brugge
Nature 482 (7385), 410-413, 2012
Mandates: US National Institutes of Health
Cancer cells co-opt the neuronal redox-sensing channel TRPA1 to promote oxidative-stress tolerance
N Takahashi, HY Chen, IS Harris, DG Stover, LM Selfors, RT Bronson, ...
Cancer cell 33 (6), 985-1003. e7, 2018
Mandates: US National Institutes of Health, Susan G. Komen
A structure-guided approach to creating covalent FGFR inhibitors
W Zhou, W Hur, U McDermott, A Dutt, W Xian, SB Ficarro, J Zhang, ...
Chemistry & biology 17 (3), 285-295, 2010
Mandates: US National Institutes of Health
Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in RAS mutant cancers
C Sun, Y Fang, J Yin, J Chen, Z Ju, D Zhang, X Chen, CP Vellano, ...
Science translational medicine 9 (392), eaal5148, 2017
Mandates: US National Institutes of Health, Susan G. Komen
Characterization of twenty-five ovarian tumour cell lines that phenocopy primary tumours
TA Ince, AD Sousa, MA Jones, JC Harrell, ES Agoston, M Krohn, ...
Nature communications 6 (1), 7419, 2015
Mandates: US National Institutes of Health
MYC regulation of a “poor-prognosis” metastatic cancer cell state
A Wolfer, BS Wittner, D Irimia, RJ Flavin, M Lupien, RN Gunawardane, ...
Proceedings of the National Academy of Sciences 107 (8), 3698-3703, 2010
Mandates: Swiss National Science Foundation, US National Institutes of Health, Howard …
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