| Developmental neurotoxicity of pyrethroid insecticides: critical review and future research needs TJ Shafer, DA Meyer, KM Crofton Environmental health perspectives 113 (2), 123-136, 2005 | 665 | 2005 |
| Transmitter, ion channel and receptor properties of pheochromocytoma (PC12) cells: a model for neurotoxicological studies. TJ Shafer, WD Atchison Neurotoxicology 12 (3), 473-492, 1991 | 474 | 1991 |
| Microelectrode arrays: a physiologically based neurotoxicity testing platform for the 21st century AFM Johnstone, GW Gross, DG Weiss, OHU Schroeder, A Gramowski, ... Neurotoxicology 31 (4), 331-350, 2010 | 458 | 2010 |
| The next generation blueprint of computational toxicology at the US Environmental Protection Agency RS Thomas, T Bahadori, TJ Buckley, J Cowden, C Deisenroth, ... Toxicological Sciences 169 (2), 317-332, 2019 | 271 | 2019 |
| Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity M Behl, JH Hsieh, TJ Shafer, WR Mundy, JR Rice, WA Boyd, ... Neurotoxicology and teratology 52, 181-193, 2015 | 207 | 2015 |
| Assessment of chemical effects on neurite outgrowth in PC12 cells using high content screening NM Radio, JM Breier, TJ Shafer, WR Mundy Toxicological sciences 105 (1), 106-118, 2008 | 198 | 2008 |
| Development of micro-electrode array based tests for neurotoxicity: assessment of interlaboratory reproducibility with neuroactive chemicals A Novellino, B Scelfo, T Palosaari, A Price, T Sobanski, TJ Shafer, ... Frontiers in neuroengineering 4, 4, 2011 | 180 | 2011 |
| Evaluation of multi-well microelectrode arrays for neurotoxicity screening using a chemical training set ER McConnell, MA McClain, J Ross, WR LeFew, TJ Shafer Neurotoxicology 33 (5), 1048-1057, 2012 | 176 | 2012 |
| Recommendation on test readiness criteria for new approach methods (NAM) in toxicology: exemplified for developmental neurotoxicity (DNT) A Bal-Price, HT Hogberg, KM Crofton, M Daneshian, RE FitzGerald, ... Altex 35 (3), 306, 2018 | 170 | 2018 |
| Effects of pyrethroids on voltage-sensitive calcium channels: a critical evaluation of strengths, weaknesses, data needs, and relationship to assessment of cumulative neurotoxicity TJ Shafer, DA Meyer Toxicology and applied pharmacology 196 (2), 303-318, 2004 | 170 | 2004 |
| Development of a high-throughput screening assay for chemical effects on proliferation and viability of immortalized human neural progenitor cells JM Breier, NM Radio, WR Mundy, TJ Shafer Toxicological Sciences 105 (1), 119-133, 2008 | 151 | 2008 |
| Neural progenitor cells as models for high-throughput screens of developmental neurotoxicity: state of the science JM Breier, K Gassmann, R Kayser, H Stegeman, D De Groot, E Fritsche, ... Neurotoxicology and teratology 32 (1), 4-15, 2010 | 143 | 2010 |
| Putative adverse outcome pathways relevant to neurotoxicity A Bal-Price, KM Crofton, M Sachana, TJ Shafer, M Behl, A Forsby, ... Critical reviews in toxicology 45 (1), 83-91, 2015 | 137 | 2015 |
| Developmental neurotoxicity testing: a path forward KM Crofton, WR Mundy, TJ Shafer Congenital anomalies 52 (3), 140-146, 2012 | 129 | 2012 |
| Mechanisms of pyrethroid insecticide-induced stimulation of calcium influx in neocortical neurons Z Cao, TJ Shafer, TF Murray Journal of Pharmacology and Experimental Therapeutics 336 (1), 197-205, 2011 | 123 | 2011 |
| Multi-well microelectrode array recordings detect neuroactivity of ToxCast compounds P Valdivia, M Martin, WR LeFew, J Ross, KA Houck, TJ Shafer Neurotoxicology 44, 204-217, 2014 | 115 | 2014 |
| In Vitro Assessment of Developmental Neurotoxicity: Use of Microelectrode Arrays to Measure Functional Changes in Neuronal Network Ontogeny BL Robinette, JA Harrill, WR Mundy, TJ Shafer Frontiers in neuroengineering 4, 1, 2011 | 113 | 2011 |
| Can the mechanisms of aluminum neurotoxicity be integrated into a unified scheme? MJ Strong, RM Garruto, JG Joshi, WR Mundy, TJ Shafer Journal of Toxicology and Environmental Health Part A 48 (6), 599-614, 1996 | 112 | 1996 |
| Developing and applying the adverse outcome pathway concept for understanding and predicting neurotoxicity A Bal-Price, PJ Lein, KP Keil, S Sethi, T Shafer, M Barenys, E Fritsche, ... Neurotoxicology 59, 240-255, 2017 | 102 | 2017 |
| Differential effects of polychlorinated biphenyl congeners on phosphoinositide hydrolysis and protein kinase C translocation in rat cerebellar granule cells PRS Kodavanti, TJ Shafer, TR Ward, WR Mundy, T Freudenrich, GJ Harry, ... Brain research 662 (1-2), 75-82, 1994 | 101 | 1994 |
