A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ... Cell 175 (4), 984-997. e24, 2018 | 1091 | 2018 |
Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF R Haq, J Shoag, P Andreu-Perez, S Yokoyama, H Edelman, GC Rowe, ... Cancer cell 23 (3), 302-315, 2013 | 870 | 2013 |
A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma S Yokoyama, SL Woods, GM Boyle, LG Aoude, S MacGregor, V Zismann, ... Nature 480 (7375), 99-103, 2011 | 570 | 2011 |
A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors DJ Konieczkowski, CM Johannessen, O Abudayyeh, JW Kim, ZA Cooper, ... Cancer discovery 4 (7), 816-827, 2014 | 551 | 2014 |
A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors M Slyper, CBM Porter, O Ashenberg, J Waldman, E Drokhlyansky, ... Nature medicine 26 (5), 792-802, 2020 | 488 | 2020 |
Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma K Bi, MX He, Z Bakouny, A Kanodia, S Napolitano, J Wu, G Grimaldi, ... Cancer cell 39 (5), 649-661. e5, 2021 | 366 | 2021 |
Clinical landscape of oncolytic virus research in 2020 N Macedo, DM Miller, R Haq, HL Kaufman Journal for immunotherapy of cancer 8 (2), 2020 | 304 | 2020 |
BCL2A1 is a lineage-specific antiapoptotic melanoma oncogene that confers resistance to BRAF inhibition R Haq, S Yokoyama, EB Hawryluk, GB Jönsson, DT Frederick, K McHenry, ... Proceedings of the National Academy of Sciences 110 (11), 4321-4326, 2013 | 281 | 2013 |
c-Met expression is regulated by Mitf in the melanocyte lineage GG McGill, R Haq, EK Nishimura, DE Fisher Journal of Biological Chemistry 281 (15), 10365-10373, 2006 | 205 | 2006 |
Constitutive p38HOG mitogen-activated protein kinase activation induces permanent cell cycle arrest and senescence R Haq, JD Brenton, M Takahashi, D Finan, R Rottapel, B Zanke Cancer research 62 (17), 5076-5082, 2002 | 176 | 2002 |
Escherichia coli Shiga toxins induce apoptosis in epithelial cells that is regulated by the Bcl-2 family NL Jones, A Islur, R Haq, M Mascarenhas, MA Karmali, MH Perdue, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 278 (5 …, 2000 | 169 | 2000 |
Biology and clinical relevance of the micropthalmia family of transcription factors in human cancer R Haq, DE Fisher Journal of Clinical Oncology 29 (25), 3474-3482, 2011 | 157 | 2011 |
Characterization of thyroid disorders in patients receiving immune checkpoint inhibition therapy H Lee, FS Hodi, A Giobbie-Hurder, PA Ott, EI Buchbinder, R Haq, ... Cancer Immunology Research 5 (12), 1133-1140, 2017 | 150 | 2017 |
Regulation of erythropoietin-induced STAT serine phosphorylation by distinct mitogen-activated protein kinases R Haq, A Halupa, BK Beattie, JM Mason, BW Zanke, DL Barber Journal of Biological Chemistry 277 (19), 17359-17366, 2002 | 113 | 2002 |
Molecular pathways: BRAF induces bioenergetic adaptation by attenuating oxidative phosphorylation R Haq, DE Fisher, HR Widlund Clinical Cancer Research 20 (9), 2257-2263, 2014 | 109 | 2014 |
PGC-1 coactivators regulate MITF and the tanning response J Shoag, R Haq, M Zhang, L Liu, GC Rowe, A Jiang, N Koulisis, C Farrel, ... Molecular cell 49 (1), 145-157, 2013 | 102 | 2013 |
Genome-wide DNA methylation analysis in melanoma reveals the importance of CpG methylation in MITF regulation M Lauss, R Haq, H Cirenajwis, B Phung, K Harbst, J Staaf, F Rosengren, ... Journal of Investigative Dermatology 135 (7), 1820-1828, 2015 | 66 | 2015 |
Integrative clinical and molecular characterization of translocation renal cell carcinoma Z Bakouny, A Sadagopan, P Ravi, NY Metaferia, J Li, S AbuHammad, ... Cell reports 38 (1), 2022 | 65 | 2022 |
YY1 regulates melanocyte development and function by cooperating with MITF J Li, JS Song, RJA Bell, TNT Tran, R Haq, H Liu, KT Love, R Langer, ... PLoS genetics 8 (5), e1002688, 2012 | 60 | 2012 |
Inactivation of Fbxw7 Impairs dsRNA Sensing and Confers Resistance to PD-1 Blockade C Gstalder, D Liu, D Miao, B Lutterbach, AL DeVine, C Lin, M Shettigar, ... Cancer discovery 10 (9), 1296-1311, 2020 | 59 | 2020 |