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Small molecules efficiently reprogram human astroglial cells into functional neurons L Zhang, JC Yin, H Yeh, NX Ma, G Lee, XA Chen, Y Wang, L Lin, L Chen, ... Cell stem cell 17 (6), 735-747, 2015 | 301 | 2015 |
DNA N6-methyladenine is dynamically regulated in the mouse brain following environmental stress B Yao, Y Cheng, Z Wang, Y Li, L Chen, L Huang, W Zhang, D Chen, H Wu, ... Nature communications 8 (1), 1-10, 2017 | 214 | 2017 |
GMPR: A robust normalization method for zero-inflated count data with application to microbiome sequencing data L Chen, J Reeve, L Zhang, S Huang, X Wang, J Chen PeerJ 6, e4600, 2018 | 210 | 2018 |
Molecular signatures associated with ZIKV exposure in human cortical neural progenitors F Zhang, C Hammack, SC Ogden, Y Cheng, EM Lee, Z Wen, X Qian, ... Nucleic acids research 44 (18), 8610-8620, 2016 | 185 | 2016 |
Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cells F Pan, TS Wingo, Z Zhao, R Gao, H Makishima, G Qu, L Lin, M Yu, ... Nature communications 8 (1), 1-10, 2017 | 118 | 2017 |
Combined loss of Tet1 and Tet2 promotes B cell, but not myeloid malignancies, in mice Z Zhao, L Chen, MM Dawlaty, F Pan, O Weeks, Y Zhou, Z Cao, H Shi, ... Cell reports 13 (8), 1692-1704, 2015 | 113 | 2015 |
Ten-eleven translocation 2 interacts with forkhead box O3 and regulates adult neurogenesis X Li, B Yao, L Chen, Y Kang, Y Li, Y Cheng, L Li, L Lin, Z Wang, M Wang, ... Nature communications 8 (1), 1-14, 2017 | 105 | 2017 |
A Bayesian mixture model for clustering droplet-based single-cell transcriptomic data from population studies Z Sun, L Chen, H Xin, Y Jiang, Q Huang, AR Cillo, T Tabib, JK Kolls, ... Nature communications 10 (1), 1-10, 2019 | 73 | 2019 |
DIVAN: accurate identification of non-coding disease-specific risk variants using multi-omics profiles L Chen, P Jin, ZS Qin Genome biology 17 (1), 1-21, 2016 | 71 | 2016 |
Active N6-methyladenine demethylation by DMAD regulates gene expression by coordinating with polycomb protein in neurons B Yao, Y Li, Z Wang, L Chen, M Poidevin, C Zhang, L Lin, F Wang, H Bao, ... Molecular cell 71 (5), 848-857. e6, 2018 | 70 | 2018 |
Altering 5-hydroxymethylcytosine modification impacts ischemic brain injury Z Miao, Y He, N Xin, M Sun, L Chen, L Lin, J Li, J Kong, P Jin, X Xu Human molecular genetics 24 (20), 5855-5866, 2015 | 64 | 2015 |
A novel statistical method for quantitative comparison of multiple ChIP-seq datasets L Chen, C Wang, ZS Qin, H Wu Bioinformatics 31 (12), 1889-1896, 2015 | 62 | 2015 |
Ten-Eleven Translocation Proteins Modulate the Response to Environmental Stress in Mice Y Cheng, M Sun, L Chen, Y Li, L Lin, B Yao, Z Li, Z Wang, J Chen, Z Miao, ... Cell reports 25 (11), 3194-3203. e4, 2018 | 58 | 2018 |
hmChIP: a database and web server for exploring publicly available human and mouse ChIP-seq and ChIP-chip data L Chen, G Wu, H Ji Bioinformatics 27 (10), 1447-1448, 2011 | 56 | 2011 |
Genome-wide alterations in hippocampal 5-hydroxymethylcytosine links plasticity genes to acute stress S Li, LA Papale, Q Zhang, A Madrid, L Chen, P Chopra, S Keleş, P Jin, ... Neurobiology of disease 86, 99-108, 2016 | 55 | 2016 |
Predictive modeling of microbiome data using a phylogeny-regularized generalized linear mixed model J Xiao, L Chen, S Johnson, Y Yu, X Zhang, J Chen Frontiers in microbiology 9, 1391, 2018 | 49 | 2018 |
Genome-wide circadian rhythm detection methods: systematic evaluations and practical guidelines JY Mei W, Jiang Z, Chen Y, Chen L, Sancar A Briefings in Bioinformatics, 1-13, 2020 | 43* | 2020 |
Risk Factors of Fluoropyrimidine Induced Cardiotoxicity Among Cancer Patients: A Systematic Review and Meta-analysis C Li, S Ngorsuraches, C Chou, L Chen, J Qian Critical Reviews in Oncology/Hematology, 103346, 2021 | 40 | 2021 |
5-hydroxymethylcytosine is dynamically regulated during forebrain organoid development and aberrantly altered in Alzheimer’s disease JN Kuehner, J Chen, EC Bruggeman, F Wang, Y Li, C Xu, ZT McEachin, ... Cell Reports 35 (4), 109042, 2021 | 31 | 2021 |