A combinatorial library of lipid-like materials for delivery of RNAi therapeutics A Akinc, A Zumbuehl, M Goldberg, ES Leshchiner, V Busini, N Hossain, ... Nature biotechnology 26 (5), 561-569, 2008 | 1455 | 2008 |
Reprogramming human T cell function and specificity with non-viral genome targeting TL Roth, C Puig-Saus, R Yu, E Shifrut, J Carnevale, PJ Li, J Hiatt, J Saco, ... Nature 559 (7714), 405-409, 2018 | 799 | 2018 |
Polymeric materials for gene delivery and DNA vaccination DN Nguyen, JJ Green, JM Chan, R Langer, DG Anderson Advanced Materials 21 (8), 847-867, 2009 | 340 | 2009 |
Molecularly engineered poly (ortho ester) microspheres for enhanced delivery of DNA vaccines C Wang, Q Ge, D Ting, D Nguyen, HR Shen, J Chen, HN Eisen, J Heller, ... Nature Materials 3 (3), 190-196, 2004 | 316 | 2004 |
Test performance evaluation of SARS-CoV-2 serological assays JD Whitman, J Hiatt, CT Mowery, BR Shy, R Yu, TN Yamamoto, U Rathore, ... Nature biotechnology 38 (10), 1174, 2020 | 268 | 2020 |
Evaluation of SARS-CoV-2 serology assays reveals a range of test performance JD Whitman, J Hiatt, CT Mowery, BR Shy, R Yu, TN Yamamoto, U Rathore, ... Nature biotechnology 38 (10), 1174-1183, 2020 | 256 | 2020 |
Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency DN Nguyen, TL Roth, PJ Li, PA Chen, R Apathy, MR Mamedov, LT Vo, ... Nature Biotechnology 38 (1), 44-49, 2020 | 244 | 2020 |
SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood DL Ng, GM Goldgof, BR Shy, AG Levine, J Balcerek, SP Bapat, J Prostko, ... Nature Communications 11 (1), 1-7, 2020 | 201 | 2020 |
Pooled knockin targeting for genome engineering of cellular immunotherapies TL Roth, PJ Li, F Blaeschke, JF Nies, R Apathy, C Mowery, R Yu, ... Cell 181 (3), 728-744. e21, 2020 | 172 | 2020 |
Small molecule end group of linear polymer determines cell-type gene delivery efficacy J Sunshine, JJ Green, KP Mahon, F Yang, AA Eltoukhy, DN Nguyen, ... Advanced materials (Deerfield Beach, Fla.) 21 (48), 4947, 2009 | 128 | 2009 |
Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery DN Nguyen, KP Mahon, G Chikh, P Kim, H Chung, AP Vicari, KT Love, ... Proceedings of the National Academy of Sciences 109 (14), E797-E803, 2012 | 127 | 2012 |
Targeted delivery of CRISPR-Cas9 and transgenes enables complex immune cell engineering JR Hamilton, CA Tsuchida, DN Nguyen, BR Shy, ER McGarrigle, ... Cell reports 35 (9), 2021 | 117 | 2021 |
Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair B Wienert, DN Nguyen, A Guenther, SJ Feng, MN Locke, SK Wyman, ... Nature communications 11 (1), 2109, 2020 | 106 | 2020 |
Drug delivery–mediated control of RNA immunostimulation DN Nguyen, SCY Chen, J Lu, M Goldberg, P Kim, A Sprague, ... Molecular Therapy 17 (9), 1555-1562, 2009 | 106 | 2009 |
High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails BR Shy, VS Vykunta, A Ha, A Talbot, TL Roth, DN Nguyen, WG Pfeifer, ... Nature biotechnology 41 (4), 521-531, 2023 | 105 | 2023 |
XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment Y Lee, D Bogdanoff, Y Wang, GC Hartoularos, JM Woo, CT Mowery, ... Science advances 7 (17), eabg4755, 2021 | 97 | 2021 |
Modulation of the immune response DHN Nguyen, DG Anderson, RS Langer, KP Mahon US Patent App. 13/126,260, 2012 | 87 | 2012 |
A diagnostic host response biosignature for COVID-19 from RNA profiling of nasal swabs and blood DL Ng, AC Granados, YA Santos, V Servellita, GM Goldgof, C Meydan, ... Science advances 7 (6), eabe5984, 2021 | 83 | 2021 |
A novel high‐throughput cell‐based method for integrated quantification of type I interferons and in vitro screening of immunostimulatory RNA drug delivery DN Nguyen, P Kim, L Martínez‐Sobrido, B Beitzel, A García‐Sastre, ... Biotechnology and bioengineering 103 (4), 664-675, 2009 | 78 | 2009 |
Enhancement of poly (orthoester) microspheres for DNA vaccine delivery by blending with poly (ethylenimine) DN Nguyen, SS Raghavan, LM Tashima, EC Lin, SJ Fredette, RS Langer, ... Biomaterials 29 (18), 2783-2793, 2008 | 73 | 2008 |