| N+-C-H···O Hydrogen bonds in protein-ligand complexes Y Itoh, Y Nakashima, S Tsukamoto, T Kurohara, M Suzuki, Y Sakae, ... Scientific reports 9 (1), 767, 2019 | 121 | 2019 |
| Design, synthesis, and biological evaluation of lysine demethylase 5 C degraders T Iida, Y Itoh, Y Takahashi, Y Yamashita, T Kurohara, Y Miyake, M Oba, ... ChemMedChem 16 (10), 1609-1618, 2021 | 24 | 2021 |
| Identification of diketopiperazine-containing 2-anilinobenzamides as potent sirtuin 2 (SIRT2)-Selective inhibitors targeting the “selectivity pocket”, substrate-binding site … P Mellini, Y Itoh, EE Elboray, H Tsumoto, Y Li, M Suzuki, Y Takahashi, ... Journal of medicinal chemistry 62 (12), 5844-5862, 2019 | 23 | 2019 |
| CF 3-Substituted semisquarate: a pluripotent building block for the divergent synthesis of trifluoromethylated functional molecules Y Yamamoto, T Kurohara, M Shibuya Chemical Communications 51 (91), 16357-16360, 2015 | 22 | 2015 |
| Synthesis of β-allylbutenolides via one-pot copper-catalyzed hydroallylation/cyclization of γ-hydroxybutynoate derivatives Y Yamamoto, S Shibano, T Kurohara, M Shibuya The Journal of Organic Chemistry 79 (10), 4503-4511, 2014 | 22 | 2014 |
| Peptide stapling improves the sustainability of a peptide-based chimeric molecule that induces targeted protein degradation H Yokoo, N Ohoka, M Takyo, T Ito, K Tsuchiya, T Kurohara, K Fukuhara, ... International Journal of Molecular Sciences 22 (16), 8772, 2021 | 15 | 2021 |
| Metalloprotein-catalyzed click reaction for in situ generation of a potent inhibitor Y Miyake, Y Itoh, Y Suzuma, H Kodama, T Kurohara, Y Yamashita, ... ACS Catalysis 10 (10), 5383-5392, 2020 | 14 | 2020 |
| Development of Rapid and Facile Solid‐Phase Synthesis of PROTACs via a Variety of Binding Styles H Xu, T Kurohara, R Takano, H Yokoo, N Shibata, N Ohoka, T Inoue, ... ChemistryOpen 11 (7), e202200131, 2022 | 12 | 2022 |
| Helical foldamers and stapled peptides as new modalities in drug discovery: modulators of protein-protein interactions K Tsuchiya, T Kurohara, K Fukuhara, T Misawa, Y Demizu Processes 10 (5), 924, 2022 | 12 | 2022 |
| Identification of ortho-hydroxy anilide as a novel scaffold for lysine demethylase 5 inhibitors P Jaikhan, B Buranrat, Y Itoh, J Chotitumnavee, T Kurohara, T Suzuki Bioorganic & Medicinal Chemistry Letters 29 (10), 1173-1176, 2019 | 8 | 2019 |
| Electrophilic Derivatization of Trifluoromethyl‐Substituted Semisquarate Using Unsaturated Organosilanes and Subsequent Ring Transformations T Kurohara, M Shibuya, Y Yamamoto Advanced Synthesis & Catalysis 359 (8), 1413-1419, 2017 | 8 | 2017 |
| In silico optimization of peptides that inhibit Wnt/β-catenin signaling M Fujita, K Tsuchiya, T Kurohara, K Fukuhara, T Misawa, Y Demizu Bioorganic & Medicinal Chemistry 84, 117264, 2023 | 7 | 2023 |
| Discovery of novel tetrahydrobenzo [b] thiophene-3-carbonitriles as histone deacetylase inhibitors P Gediya, VK Vyas, V Carafa, N Sitwala, L Della Torre, A Poziello, ... Bioorganic Chemistry 110, 104801, 2021 | 7 | 2021 |
| Synthesis of γ-trifluoromethyl tetronate derivatives from squarates Y Yamamoto, Y Takamizu, T Kurohara, M Shibuya Heterocycles 95 (1), 525-539, 2017 | 7 | 2017 |
| Development of a penetratin-conjugated stapled peptide that inhibits Wnt/β-catenin signaling K Tsuchiya, M Kiyoshi, N Hashii, M Fujita, T Kurohara, A Ishii-Watabe, ... Bioorganic & Medicinal Chemistry 73, 117021, 2022 | 6 | 2022 |
| Synthesis of Alkoxycarbonyldifluoromethyl-Substituted Semisquarates and Their Transformations T Kurohara, J Jiyue, M Shibuya, Y Yamamoto Synthesis 50 (08), 1687-1698, 2018 | 6 | 2018 |
| Structure–activity relationship study of PROTACs against hematopoietic prostaglandin D 2 synthase Y Murakami, H Osawa, T Kurohara, Y Yanase, T Ito, H Yokoo, N Shibata, ... RSC Medicinal Chemistry 13 (12), 1495-1503, 2022 | 5 | 2022 |
| Identification of Novel Histone Deacetylase 6‐Selective Inhibitors Bearing 3, 3, 3‐Trifluorolactic Amide (TFLAM) Motif as a Zinc Binding Group T Kurohara, K Tanaka, D Takahashi, S Ueda, Y Yamashita, Y Takada, ... Chembiochem 22 (22), 3158-3163, 2021 | 5 | 2021 |
| Development of versatile solid-phase methods for syntheses of PROTACs with diverse E3 ligands H Xu, T Kurohara, N Ohoka, G Tsuji, T Inoue, M Naito, Y Demizu Bioorganic & Medicinal Chemistry 86, 117293, 2023 | 4 | 2023 |
| Cancer-Cell-Selective Targeting by Arylcyclopropylamine–Vorinostat Conjugates Y Ota, Y Itoh, T Kurohara, R Singh, EE Elboray, C Hu, F Zamani, ... ACS Medicinal Chemistry Letters 13 (10), 1568-1573, 2022 | 4 | 2022 |
Takayoshi SuzukiOsaka UniversityVerified email at sanken.osaka-u.ac.jp
