Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis T Kisseleva, H Uchinami, N Feirt, O Quintana-Bustamante, JC Segovia, ... Journal of hepatology 45 (3), 429-438, 2006 | 628 | 2006 |
Hematopoietic mobilization in mice increases the presence of bone marrow–derived hepatocytes via in vivo cell fusion O Quintana‐Bustamante, A Alvarez‐Barrientos, AV Kofman, I Fabregat, ... Hepatology 43 (1), 108-116, 2006 | 144 | 2006 |
Hematopoietic dysfunction in a mouse model for Fanconi anemia group D1 S Navarro, NW Meza, O Quintana-Bustamante, JA Casado, A Jacome, ... Molecular Therapy 14 (4), 525-535, 2006 | 133 | 2006 |
The current status of mesenchymal stromal cells: controversies, unresolved issues and some promising solutions to improve their therapeutic efficacy D García-Bernal, M García-Arranz, RM Yáñez, R Hervás-Salcedo, ... Frontiers in Cell and Developmental Biology 9, 650664, 2021 | 110 | 2021 |
In vivo CRISPR/Cas9 targeting of fusion oncogenes for selective elimination of cancer cells M Martinez-Lage, R Torres-Ruiz, P Puig-Serra, P Moreno-Gaona, ... Nature communications 11 (1), 5060, 2020 | 94 | 2020 |
Targeted gene therapy and cell reprogramming in F anconi anemia P Rio, R Baños, A Lombardo, O Quintana‐Bustamante, L Alvarez, ... EMBO molecular medicine 6 (6), 835-848, 2014 | 93 | 2014 |
Reprogramming human B cells into induced pluripotent stem cells and its enhancement by C/EBPα C Bueno, JL Sardina, B Di Stefano, D Romero-Moya, A Muñoz-López, ... Leukemia 30 (3), 674-682, 2016 | 56 | 2016 |
Rescue of pyruvate kinase deficiency in mice by gene therapy using the human isoenzyme NW Meza, ME Alonso-Ferrero, S Navarro, O Quintana-Bustamante, ... Molecular Therapy 17 (12), 2000-2009, 2009 | 42 | 2009 |
Generation of a high number of healthy erythroid cells from gene-edited pyruvate kinase deficiency patient-specific induced pluripotent stem cells Z Garate, O Quintana-Bustamante, AM Crane, E Olivier, L Poirot, ... Stem Cell Reports 5 (6), 1053-1066, 2015 | 39 | 2015 |
New frontier in regenerative medicine: site-specific gene correction in patient-specific induced pluripotent stem cells Z Garate, BR Davis, O Quintana-Bustamante, JC Segovia Human Gene Therapy 24 (6), 571-583, 2013 | 37 | 2013 |
Enhanced anti-inflammatory effects of mesenchymal stromal cells mediated by the transient ectopic expression of CXCR4 and IL10 R Hervás-Salcedo, M Fernández-García, M Hernando-Rodríguez, ... Stem Cell Research & Therapy 12, 1-20, 2021 | 31 | 2021 |
Gene editing of PKLR gene in human hematopoietic progenitors through 5’ and 3’ UTR modified TALEN mRNA O Quintana-Bustamante, S Fañanas-Baquero, I Orman, R Torres, ... PLoS One 14 (10), e0223775, 2019 | 27 | 2019 |
Highly efficient genome editing of human hematopoietic stem cells via a nano-silicon-blade delivery approach Y Ma, X Han, O Quintana Bustamante, R Bessa de Castro, K Zhang, ... Integrative Biology 9 (6), 548-554, 2017 | 27 | 2017 |
Advances in the gene therapy of monogenic blood cell diseases JA Bueren, O Quintana‐Bustamante, E Almarza, S Navarro, P Río, ... Clinical genetics 97 (1), 89-102, 2020 | 26 | 2020 |
Overexpression of wild-type or mutants forms of CEBPA alter normal human hematopoiesis O Quintana-Bustamante, S Smith, E Griessinger, Y Reyal, J Vargaftig, ... Leukemia 26 (7), 1537-1546, 2012 | 25 | 2012 |
In Vitro and In Vivo Expression of Human Erythrocyte Pyruvate Kinase in Erythroid Cells: A Gene Therapy Approach NW Meza, O Quintana-Bustamante, A Puyet, P Rio, S Navarro, A Diez, ... Human gene therapy 18 (6), 502-514, 2007 | 23 | 2007 |
Generation of iPSCs from Genetically Corrected Brca2 Hypomorphic Cells: Implications in Cell Reprogramming and Stem Cell Therapy S Navarro, V Moleiro, FJ Molina-Estevez, ML Lozano, R Chinchon, ... Stem Cells 32 (2), 436-446, 2014 | 20 | 2014 |
Natural estrogens enhance the engraftment of human hematopoietic stem and progenitor cells in immunodeficient mice S Fañanas-Baquero, I Orman, FB Aparicio, SB de Miguel, JG Merino, ... haematologica 106 (6), 1659, 2021 | 19 | 2021 |
Cell fusion reprogramming leads to a specific hepatic expression pattern during mouse bone marrow derived hepatocyte formation in vivo O Quintana-Bustamante, E Grueso, R Garcia-Escudero, E Arza, ... PloS one 7 (3), e33945, 2012 | 18 | 2012 |
Clinically relevant gene editing in hematopoietic stem cells for the treatment of pyruvate kinase deficiency S Fañanas-Baquero, O Quintana-Bustamante, DP Dever, O Alberquilla, ... Molecular Therapy Methods & Clinical Development 22, 237-248, 2021 | 15 | 2021 |