Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets RD Michalek, VA Gerriets, SR Jacobs, AN Macintyre, NJ MacIver, ... The Journal of immunology 186 (6), 3299-3303, 2011 | 2158 | 2011 |
Phosphoenolpyruvate is a metabolic checkpoint of anti-tumor T cell responses PC Ho, JD Bihuniak, AN Macintyre, M Staron, X Liu, R Amezquita, ... Cell 162 (6), 1217-1228, 2015 | 1293 | 2015 |
The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function AN Macintyre, VA Gerriets, AG Nichols, RD Michalek, MC Rudolph, ... Cell metabolism 20 (1), 61-72, 2014 | 1124 | 2014 |
Metabolic reprogramming of macrophages: glucose transporter 1 (GLUT1)-mediated glucose metabolism drives a proinflammatory phenotype AJ Freemerman, AR Johnson, GN Sacks, JJ Milner, EL Kirk, MA Troester, ... Journal of Biological Chemistry 289 (11), 7884-7896, 2014 | 904 | 2014 |
Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation VA Gerriets, RJ Kishton, AG Nichols, AN Macintyre, M Inoue, O Ilkayeva, ... The Journal of clinical investigation 125 (1), 194-207, 2015 | 695 | 2015 |
Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites H Guo, WC Chou, Y Lai, K Liang, JW Tam, WJ Brickey, L Chen, ... Science 370 (6516), eaay9097, 2020 | 352 | 2020 |
Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism AN Macintyre, D Finlay, G Preston, LV Sinclair, CM Waugh, P Tamas, ... Immunity 34 (2), 224-236, 2011 | 295 | 2011 |
In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies D Li, RJ Edwards, K Manne, DR Martinez, A Schäfer, SM Alam, K Wiehe, ... Cell 184 (16), 4203-4219. e32, 2021 | 261 | 2021 |
AMPK is essential to balance glycolysis and mitochondrial metabolism to control T-ALL cell stress and survival RJ Kishton, CE Barnes, AG Nichols, S Cohen, VA Gerriets, PJ Siska, ... Cell metabolism 23 (4), 649-662, 2016 | 237 | 2016 |
Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells Y Cao, JC Rathmell, AN Macintyre PloS one 9 (8), e104104, 2014 | 173 | 2014 |
Compartmentalization of cAMP-dependent signaling by phosphodiesterase-4D is involved in the regulation of vasopressin-mediated water reabsorption in renal principal cells E Stefan, B Wiesner, GS Baillie, R Mollajew, V Henn, D Lorenz, J Furkert, ... Journal of the American Society of Nephrology 18 (1), 199-212, 2007 | 169 | 2007 |
Antigen receptor control of methionine metabolism in T cells LV Sinclair, AJM Howden, A Brenes, L Spinelli, JL Hukelmann, ... Elife 8, e44210, 2019 | 162 | 2019 |
Autophagy is essential to suppress cell stress and to allow BCR-Abl-mediated leukemogenesis BJ Altman, SR Jacobs, EF Mason, RD Michalek, AN MacIntyre, JL Coloff, ... Oncogene 30 (16), 1855-1867, 2011 | 154 | 2011 |
Akt-dependent glucose metabolism promotes Mcl-1 synthesis to maintain cell survival and resistance to Bcl-2 inhibition JL Coloff, AN Macintyre, AG Nichols, T Liu, CA Gallo, DR Plas, ... Cancer research 71 (15), 5204-5213, 2011 | 144 | 2011 |
Activated lymphocytes as a metabolic model for carcinogenesis AN Macintyre, JC Rathmell Cancer & metabolism 1, 1-12, 2013 | 119 | 2013 |
LKB1 is essential for the proliferation of T‐cell progenitors and mature peripheral T cells P Tamás, A Macintyre, D Finlay, R Clarke, C Feijoo‐Carnero, A Ashworth, ... European journal of immunology 40 (1), 242-253, 2010 | 103 | 2010 |
Glucose transporter 1-mediated glucose uptake is limiting for B-cell acute lymphoblastic leukemia anabolic metabolism and resistance to apoptosis T Liu, RJ Kishton, AN Macintyre, VA Gerriets, H Xiang, X Liu, ED Abel, ... Cell death & disease 5 (10), e1470-e1470, 2014 | 82 | 2014 |
Acetalated dextran microparticles for codelivery of STING and TLR7/8 agonists MA Collier, RD Junkins, MD Gallovic, BM Johnson, MM Johnson, ... Molecular pharmaceutics 15 (11), 4933-4946, 2018 | 80 | 2018 |
The serogroup B meningococcal outer membrane vesicle-based vaccine 4CMenB induces cross-species protection against Neisseria gonorrhoeae I Leduc, KL Connolly, A Begum, K Underwood, S Darnell, WM Shafer, ... PLoS pathogens 16 (12), e1008602, 2020 | 77 | 2020 |
The functions of SARS-CoV-2 neutralizing and infection-enhancing antibodies in vitro and in mice and nonhuman primates D Li, RJ Edwards, K Manne, DR Martinez, A Schäfer, SM Alam, K Wiehe, ... BioRxiv, 2020.12. 31.424729, 2021 | 63 | 2021 |