| Unique carbohydrate–carbohydrate interactions are required for high affinity binding between FcγRIII and antibodies lacking core fucose C Ferrara, S Grau, C Jäger, P Sondermann, P Brünker, I Waldhauer, ... Proceedings of the National Academy of Sciences 108 (31), 12669-12674, 2011 | 927 | 2011 |
| A novel partial agonist of peroxisome proliferator-activated receptor-γ (PPARγ) recruits PPARγ-coactivator-1α, prevents triglyceride accumulation, and potentiates insulin … E Burgermeister, A Schnoebelen, A Flament, J Benz, M Stihle, B Gsell, ... Molecular Endocrinology 20 (4), 809-830, 2006 | 214 | 2006 |
| Structural properties of AMP-activated protein kinase: dimerization, molecular shape, and changes upon ligand binding U Riek, R Scholz, P Konarev, A Rufer, M Suter, A Nazabal, P Ringler, ... Journal of Biological Chemistry 283 (26), 18331-18343, 2008 | 111 | 2008 |
| A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation H Zhao, R Ghirlando, C Alfonso, F Arisaka, I Attali, DL Bain, MM Bakhtina, ... PloS one 10 (5), e0126420, 2015 | 98 | 2015 |
| Structural insight into function and regulation of carnitine palmitoyltransferase AC Rufer, R Thoma, M Hennig Cellular and molecular life sciences 66, 2489-2501, 2009 | 92 | 2009 |
| Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody P Favuzza, E Guffart, M Tamborrini, B Scherer, AM Dreyer, AC Rufer, ... Elife 6, e20383, 2017 | 76 | 2017 |
| The crystal structure of carnitine palmitoyltransferase 2 and implications for diabetes treatment AC Rufer, R Thoma, J Benz, M Stihle, B Gsell, E De Roo, DW Banner, ... Structure 14 (4), 713-723, 2006 | 70 | 2006 |
| Structure and function of purified monoclonal antibody dimers induced by different stress conditions R Paul, A Graff-Meyer, H Stahlberg, ME Lauer, AC Rufer, H Beck, ... Pharmaceutical research 29, 2047-2059, 2012 | 69 | 2012 |
| Real-time monitoring of binding events on a thermostabilized human A2A receptor embedded in a lipid bilayer by surface plasmon resonance N Bocquet, J Kohler, MN Hug, EA Kusznir, AC Rufer, RJ Dawson, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (5), 1224-1233, 2015 | 65 | 2015 |
| Generation, characterization and structural data of chymase binding proteins based on the human Fyn kinase SH3 domain D Schlatter, S Brack, DW Banner, S Batey, J Benz, J Bertschinger, ... MAbs 4 (4), 497-508, 2012 | 61 | 2012 |
| Cathepsin S inhibition combines control of systemic and peripheral pathomechanisms of autoimmune tissue injury M Tato, SV Kumar, Y Liu, SR Mulay, S Moll, B Popper, JN Eberhard, ... Scientific reports 7 (1), 2775, 2017 | 58 | 2017 |
| Drug discovery for enzymes AC Rufer Drug discovery today 26 (4), 875-886, 2021 | 51 | 2021 |
| Dimerization-induced activation of soluble insulin/IGF-1 receptor kinases: an alternative mechanism of activation K Baer, H Al-Hasani, S Parvaresch, T Corona, A Rufer, V Nölle, ... Biochemistry 40 (47), 14268-14278, 2001 | 46 | 2001 |
| Development of high-specificity fluorescent probes to enable cannabinoid type 2 receptor studies in living cells RC Sarott, MV Westphal, P Pfaff, C Korn, DA Sykes, T Gazzi, B Brennecke, ... Journal of the American Chemical Society 142 (40), 16953-16964, 2020 | 40 | 2020 |
| Characterization of mAb dimers reveals predominant dimer forms common in therapeutic mAbs F Plath, P Ringler, A Graff-Meyer, H Stahlberg, ME Lauer, AC Rufer, ... MAbs 8 (5), 928-940, 2016 | 39 | 2016 |
| Mapping the conformational space accessible to BACE2 using surface mutants and cocrystals with Fab fragments, Fynomers and Xaperones DW Banner, B Gsell, J Benz, J Bertschinger, D Burger, S Brack, ... Acta Crystallographica Section D: Biological Crystallography 69 (6), 1124-1137, 2013 | 39 | 2013 |
| Cholesteryl ester transfer between lipoproteins does not require a ternary tunnel complex with CETP ME Lauer, A Graff-Meyer, AC Rufer, C Maugeais, E von der Mark, ... Journal of structural biology 194 (2), 191-198, 2016 | 36 | 2016 |
| Isothermal titration calorimetry with micelles: thermodynamics of inhibitor binding to carnitine palmitoyltransferase 2 membrane protein S Perspicace, AC Rufer, R Thoma, F Mueller, M Hennig, S Ceccarelli, ... FEBS open bio 3, 204-211, 2013 | 33 | 2013 |
| Potent and selective BACE-1 peptide inhibitors lower brain Aβ levels mediated by brain shuttle transport N Ruderisch, D Schlatter, A Kuglstatter, W Guba, S Huber, C Cusulin, ... EBioMedicine 24, 76-92, 2017 | 29 | 2017 |
| A novel selective inverse agonist of the CB2 receptor as a radiolabeled tool compound for kinetic binding studies A Martella, H Sijben, AC Rufer, U Grether, J Fingerle, C Ullmer, T Hartung, ... Molecular Pharmacology 92 (4), 389-400, 2017 | 27 | 2017 |
