Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments B Peck, ZT Schug, Q Zhang, B Dankworth, DT Jones, E Smethurst, ... Cancer & metabolism 4, 1-18, 2016 | 233 | 2016 |
2, 4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer A Blomme, CA Ford, E Mui, R Patel, C Ntala, LE Jamieson, M Planque, ... Nature Communications 11 (1), 2508, 2020 | 137 | 2020 |
Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer I Ahmad, E Mui, L Galbraith, R Patel, EH Tan, M Salji, AG Rust, ... Proceedings of the National Academy of Sciences 113 (29), 8290-8295, 2016 | 124 | 2016 |
Plakophilin3 downregulation leads to a decrease in cell adhesion and promotes metastasis ST Kundu, P Gosavi, N Khapare, R Patel, AS Hosing, GB Maru, A Ingle, ... International journal of cancer 123 (10), 2303-2314, 2008 | 108 | 2008 |
Sprouty2, PTEN, and PP2A interact to regulate prostate cancer progression R Patel, M Gao, I Ahmad, J Fleming, LB Singh, TS Rai, AB McKie, ... The Journal of clinical investigation 123 (3), 1157-1175, 2013 | 100 | 2013 |
Ras mutation cooperates with β-catenin activation to drive bladder tumourigenesis I Ahmad, R Patel, Y Liu, LB Singh, MM Taketo, XR Wu, HY Leung, ... Cell death & disease 2 (3), e124-e124, 2011 | 97 | 2011 |
Polymeric black tea polyphenols induce phase II enzymes via Nrf2 in mouse liver and lungs R Patel, G Maru Free Radical Biology and Medicine 44 (11), 1897-1911, 2008 | 89 | 2008 |
Polymeric black tea polyphenols inhibit 1, 2-dimethylhydrazine induced colorectal carcinogenesis by inhibiting cell proliferation via Wnt/β-catenin pathway R Patel, A Ingle, GB Maru Toxicology and applied pharmacology 227 (1), 136-146, 2008 | 73 | 2008 |
HER2 overcomes PTEN (loss)-induced senescence to cause aggressive prostate cancer I Ahmad, R Patel, LB Singh, C Nixon, M Seywright, RJ Barnetson, ... Proceedings of the National Academy of Sciences 108 (39), 16392-16397, 2011 | 71 | 2011 |
Targeting the EGFR-family for therapy: biological challenges and clinical perspective R Patel, H Y Leung Current pharmaceutical design 18 (19), 2672-2679, 2012 | 67 | 2012 |
Dietary turmeric modulates DMBA-induced p21ras, MAP kinases and AP-1/NF-κB pathway to alter cellular responses during hamster buccal pouch carcinogenesis R Garg, A Ingle, G Maru Toxicology and applied pharmacology 232 (3), 428-439, 2008 | 59 | 2008 |
SPRY2 loss enhances ErbB trafficking and PI3K/AKT signalling to drive human and mouse prostate carcinogenesis M Gao, R Patel, I Ahmad, J Fleming, J Edwards, S McCracken, ... EMBO molecular medicine 4 (8), 776-790, 2012 | 58 | 2012 |
Chemopreventive herbal anti-oxidants: current status and future perspectives R Patel, R Garg, S Erande, GB Maru Journal of clinical biochemistry and nutrition 40 (2), 82-91, 2007 | 54 | 2007 |
Polymeric black tea polyphenols inhibit mouse skin chemical carcinogenesis by decreasing cell proliferation R Patel, R Krishnan, A Ramchandani, G Maru Cell Proliferation 41 (3), 532-553, 2008 | 50 | 2008 |
Elevated LIM kinase 1 in nonmetastatic prostate cancer reflects its role in facilitating androgen receptor nuclear translocation K Mardilovich, M Gabrielsen, L McGarry, C Orange, R Patel, E Shanks, ... Molecular cancer therapeutics 14 (1), 246-258, 2015 | 40 | 2015 |
Activation of β-catenin cooperates with loss of Pten to drive AR-independent castration-resistant prostate cancer R Patel, EA Brzezinska, P Repiscak, I Ahmad, E Mui, M Gao, A Blomme, ... Cancer Research 80 (3), 576-590, 2020 | 39 | 2020 |
Repurposing screen identifies mebendazole as a clinical candidate to synergise with docetaxel for prostate cancer treatment LK Rushworth, K Hewit, S Munnings-Tomes, S Somani, D James, ... British journal of cancer 122 (4), 517-527, 2020 | 38 | 2020 |
Increased T-cell Infiltration Elicited by Erk5 Deletion in a Pten-Deficient Mouse Model of Prostate Carcinogenesis CJ Loveridge, EJ Mui, R Patel, EH Tan, I Ahmad, M Welsh, J Galbraith, ... Cancer research 77 (12), 3158-3168, 2017 | 29 | 2017 |
Sprouty2 loss‐induced IL 6 drives castration‐resistant prostate cancer through scavenger receptor B1 R Patel, J Fleming, E Mui, C Loveridge, P Repiscak, A Blomme, V Harle, ... EMBO Molecular Medicine 10 (4), e8347, 2018 | 28 | 2018 |
An ARF GTPase module promoting invasion and metastasis through regulating phosphoinositide metabolism M Nacke, E Sandilands, K Nikolatou, Á Román-Fernández, S Mason, ... Nature Communications 12 (1), 1623, 2021 | 21 | 2021 |