Polymorphism of human cytochrome P450 enzymes and its clinical impact SF Zhou, JP Liu, B Chowbay Drug metabolism reviews 41 (2), 89-295, 2009 | 967 | 2009 |
A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer KP Ng, AM Hillmer, CTH Chuah, WC Juan, TK Ko, ASM Teo, ... Nature medicine 18 (4), 521-528, 2012 | 674 | 2012 |
Herbal modulation of P‐glycoprotein S Zhou, LY Lim, B Chowbay Drug metabolism reviews 36 (1), 57-104, 2004 | 522 | 2004 |
Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients B Chowbay, S Cumaraswamy, YB Cheung, Q Zhou, EJD Lee Pharmacogenetics and Genomics 13 (2), 89-95, 2003 | 360 | 2003 |
Tamoxifen metabolism predicts drug concentrations and outcome in premenopausal patients with early breast cancer P Saladores, T Mürdter, D Eccles, B Chowbay, NK Zgheib, S Winter, ... The pharmacogenomics journal 15 (1), 84-94, 2015 | 214 | 2015 |
Phase I pharmacokinetic study of a weekly liposomal paclitaxel formulation (Genexol®-PM) in patients with solid tumors WT Lim, EH Tan, CK Toh, SW Hee, SS Leong, PCS Ang, NS Wong, ... Annals of oncology 21 (2), 382-388, 2010 | 185 | 2010 |
Meta‐analysis of the influence of MDR1 C3435T polymorphism on digoxin pharmacokinetics and MDR1 gene expression B Chowbay, H Li, M David, Y Bun Cheung, EJD Lee British journal of clinical pharmacology 60 (2), 159-171, 2005 | 163 | 2005 |
Pharmacogenetics of target genes across doxorubicin disposition pathway: a review S Lal, A Mahajan, W Ning Chen, B Chowbay Current drug metabolism 11 (1), 115-128, 2010 | 160 | 2010 |
Long noncoding RNA EGFR-AS1 mediates epidermal growth factor receptor addiction and modulates treatment response in squamous cell carcinoma DSW Tan, FT Chong, HS Leong, SY Toh, DP Lau, XL Kwang, X Zhang, ... Nature medicine 23 (10), 1167-1175, 2017 | 159 | 2017 |
Role of UGT1A1*6, UGT1A1*28 and ABCG2 c.421C>A polymorphisms in irinotecan‐induced neutropenia in Asian cancer patients SR Jada, R Lim, CI Wong, X Shu, SC Lee, Q Zhou, BC Goh, B Chowbay Cancer science 98 (9), 1461-1467, 2007 | 158 | 2007 |
An interethnic comparison of polymorphisms of the genes encoding drug-metabolizing enzymes and drug transporters: experience in Singapore B Chowbay, S Zhou, EJD Lee Drug metabolism reviews 37 (2), 327-378, 2005 | 157 | 2005 |
Impact of CYP2D6, CYP3A5, CYP2C9 and CYP2C19 polymorphisms on tamoxifen pharmacokinetics in Asian breast cancer patients JSL Lim, XA Chen, O Singh, YS Yap, RCH Ng, NS Wong, M Wong, ... British journal of clinical pharmacology 71 (5), 737-750, 2011 | 156 | 2011 |
Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci T Aung, M Ozaki, MC Lee, U Schlötzer-Schrehardt, G Thorleifsson, ... Nature genetics 49 (7), 993-1004, 2017 | 145 | 2017 |
Influence of ABCB1 and ABCG2 polymorphisms on doxorubicin disposition in Asian breast cancer patients S Lal, ZW Wong, E Sandanaraj, X Xiang, PCS Ang, EJD Lee, B Chowbay Cancer science 99 (4), 816-823, 2008 | 141 | 2008 |
A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome T Aung, M Ozaki, T Mizoguchi, RR Allingham, Z Li, A Haripriya, S Nakano, ... Nature genetics 47 (4), 387-392, 2015 | 125 | 2015 |
Pharmacogenetic profiling across the irinotecan pathway in Asian patients with cancer Q Zhou, A Sparreboom, EH Tan, YB Cheung, A Lee, D Poon, EJD Lee, ... British journal of clinical pharmacology 59 (4), 415-424, 2005 | 120 | 2005 |
Pharmacogenetics of SLCO1B1 gene and the impact of* 1b and* 15 haplotypes on irinotecan disposition in Asian cancer patients X Xiang, SR Jada, HH Li, L Fan, L San Tham, CI Wong, SC Lee, R Lim, ... Pharmacogenetics and genomics 16 (9), 683-691, 2006 | 115 | 2006 |
A Phase II study of pazopanib in Asian patients with recurrent/metastatic nasopharyngeal carcinoma WT Lim, QS Ng, P Ivy, SS Leong, O Singh, B Chowbay, F Gao, CH Thng, ... Clinical cancer research 17 (16), 5481-5489, 2011 | 110 | 2011 |
Transport of cryptotanshinone, a major active triterpenoid in Salvia miltiorrhiza Bunge widely used in the treatment of stroke and Alzheimer's disease, across the blood-brain … XY Yu, SG Lin, X Chen, ZW Zhou, J Liang, W Duan, B Chowbay, JY Wen, ... Current Drug Metabolism 8 (4), 365-377, 2007 | 103 | 2007 |
Genetic risk of extranodal natural killer T-cell lymphoma: a genome-wide association study Z Li, Y Xia, LN Feng, JR Chen, HM Li, J Cui, QQ Cai, KS Sim, ... The Lancet Oncology 17 (9), 1240-1247, 2016 | 100 | 2016 |