| Structure and function of the plasminogen/plasmin system FJ Castellino, VA Ploplis Thrombosis and haemostasis 93 (04), 647-654, 2005 | 596 | 2005 |
| Effects of disruption of the plasminogen gene on thrombosis, growth, and health in mice VA Ploplis, P Carmeliet, S Vazirzadeh, I Van Vlaenderen, L Moons, ... Circulation 92 (9), 2585-2593, 1995 | 436 | 1995 |
| Early platelet dysfunction: an unrecognized role in the acute coagulopathy of trauma MV Wohlauer, EE Moore, S Thomas, A Sauaia, E Evans, J Harr, ... Journal of the American College of Surgeons 214 (5), 739-746, 2012 | 337 | 2012 |
| Tumor development is retarded in mice lacking the gene for urokinase-type plasminogen activator or its inhibitor, plasminogen activator inhibitor-1 LS Gutierrez, A Schulman, T Brito-Robinson, F Noria, VA Ploplis, ... Cancer research 60 (20), 5839-5847, 2000 | 301 | 2000 |
| Plasminogen deficiency differentially affects recruitment of inflammatory cell populations in mice VA Ploplis, EL French, P Carmeliet, D Collen, EF Plow Blood, The Journal of the American Society of Hematology 91 (6), 2005-2009, 1998 | 256 | 1998 |
| Impaired arterial neointima formation in mice with disruption of the plasminogen gene. P Carmeliet, L Moons, V Ploplis, E Plow, D Collen The Journal of clinical investigation 99 (2), 200-208, 1997 | 239 | 1997 |
| The development of bleomycin-induced pulmonary fibrosis in mice deficient for components of the fibrinolytic system CM Swaisgood, EL French, C Noga, RH Simon, VA Ploplis The American journal of pathology 157 (1), 177-187, 2000 | 223 | 2000 |
| Plasminogen and plasminogen activators protect against renal injury in crescentic glomerulonephritis AR Kitching, SR Holdsworth, VA Ploplis, EF Plow, D Collen, P Carmeliet, ... The Journal of experimental medicine 185 (5), 963-968, 1997 | 218 | 1997 |
| Bacterial plasminogen receptors utilize host plasminogen system for effective invasion and dissemination S Bhattacharya, VA Ploplis, FJ Castellino BioMed Research International 2012 (1), 482096, 2012 | 169 | 2012 |
| Platelet dysfunction is an early marker for traumatic brain injury-induced coagulopathy PK Davis, H Musunuru, M Walsh, R Cassady, R Yount, A Losiniecki, ... Neurocritical care 18, 201-208, 2013 | 167 | 2013 |
| Plasminogen has a broad extrahepatic distribution L Zhang, D Seiffert, BJ Fowler, GR Jenkins, TC Thinnes, DJ Loskutoff, ... Thrombosis and haemostasis 87 (03), 493-501, 2002 | 166 | 2002 |
| Insights in vessel development and vascular disorders using targeted inactivation and transfer of vascular endothelial growth factor, the tissue factor receptor, and the … P Carmeliet, L Moons, M Dewerchin, N Mackman, T Luther, G Breier, ... Annals of the New York Academy of Sciences 811, 191-206, 1997 | 158 | 1997 |
| Accelerated skin wound healing in plasminogen activator inhibitor-1-deficient mice JCY Chan, DA Duszczyszyn, FJ Castellino, VA Ploplis The American journal of pathology 159 (5), 1681-1688, 2001 | 144 | 2001 |
| Fibrinogen stabilizes placental-maternal attachment during embryonic development in the mouse T Iwaki, MJ Sandoval-Cooper, M Paiva, T Kobayashi, VA Ploplis, ... The American journal of pathology 160 (3), 1021-1034, 2002 | 141 | 2002 |
| Traumatic brain injury causes platelet adenosine diphosphate and arachidonic acid receptor inhibition independent of hemorrhagic shock in humans and rats FJ Castellino, MP Chapman, DL Donahue, S Thomas, EE Moore, ... Journal of Trauma and Acute Care Surgery 76 (5), 1169-1176, 2014 | 137 | 2014 |
| Molecular and cellular modulation of fibrinolysis K Kolev, R Machovich Thrombosis and haemostasis 89 (04), 610-621, 2003 | 130 | 2003 |
| Plasminogen activator inhibitor-1: the double-edged sword in apoptosis RD Balsara, VA Ploplis Thrombosis and haemostasis 100 (12), 1029-1036, 2008 | 124 | 2008 |
| A central role for plasminogen in the inflammatory response to biomaterials SJ Busuttil, VA Ploplis, FJ Castellino, L Tang, JW Eaton, EF Plow Journal of Thrombosis and Haemostasis 2 (10), 1798-1805, 2004 | 123 | 2004 |
| Reduced transplant arteriosclerosis in plasminogen-deficient mice. L Moons, C Shi, V Ploplis, E Plow, E Haber, D Collen, P Carmeliet The Journal of clinical investigation 102 (10), 1788-1797, 1998 | 116 | 1998 |
| The existence of independent domain structures in human Lys77-plasminogen. FJ Castellino, VA Ploplis, JR Powell, DK Strickland Journal of Biological Chemistry 256 (10), 4778-4782, 1981 | 115 | 1981 |
