Articles with public access mandates - Marketa ZvelebilLearn more
Not available anywhere: 1
The Identification of 2-(1H-Indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a Potent, Selective …
AJ Folkes, K Ahmadi, WK Alderton, S Alix, SJ Baker, G Box, ...
Journal of medicinal chemistry 51 (18), 5522-5532, 2008
Mandates: Cancer Research UK
Available somewhere: 21
Identification of a disease-defining gene fusion in epithelioid hemangioendothelioma
MR Tanas, A Sboner, AM Oliveira, MR Erickson-Johnson, J Hespelt, ...
Science translational medicine 3 (98), 98ra82-98ra82, 2011
Mandates: US National Institutes of Health
IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-κB as well as cell survival and oncogenesis
M Gyrd-Hansen, M Darding, M Miasari, MM Santoro, L Zender, W Xue, ...
Nature cell biology 10 (11), 1309-1317, 2008
Mandates: US National Institutes of Health
Whole genome sequencing of matched primary and metastatic acral melanomas
S Turajlic, SJ Furney, MB Lambros, C Mitsopoulos, I Kozarewa, FC Geyer, ...
Genome research 22 (2), 196-207, 2012
Mandates: Cancer Research UK
High-throughput RNA interference screening using pooled shRNA libraries and next generation sequencing
D Sims, AM Mendes-Pereira, J Frankum, D Burgess, MA Cerone, ...
Genome biology 12, 1-13, 2011
Mandates: Cancer Research UK
Inactivation of effector caspases through nondegradative polyubiquitylation
M Ditzel, M Broemer, T Tenev, C Bolduc, TV Lee, KTG Rigbolt, R Elliott, ...
Molecular cell 32 (4), 540-553, 2008
Mandates: US National Institutes of Health, German Research Foundation
Cholesterol biosynthesis pathway as a novel mechanism of resistance to estrogen deprivation in estrogen receptor-positive breast cancer
N Simigdala, Q Gao, S Pancholi, H Roberg-Larsen, M Zvelebil, R Ribas, ...
Breast Cancer Research 18, 1-14, 2016
Mandates: Breast Cancer Now, UK, National Institute for Health Research, UK
Ubiquitylation of the initiator caspase DREDD is required for innate immune signalling
A Meinander, C Runchel, T Tenev, L Chen, CH Kim, PS Ribeiro, ...
The EMBO journal 31 (12), 2770-2783, 2012
Mandates: US National Institutes of Health
5-(4, 6-Dimorpholino-1, 3, 5-triazin-2-yl)-4-(trifluoromethyl) pyridin-2-amine (PQR309), a potent, brain-penetrant, orally bioavailable, pan-class I PI3K/mTOR inhibitor as …
F Beaufils, N Cmiljanovic, V Cmiljanovic, T Bohnacker, A Melone, ...
Journal of medicinal chemistry 60 (17), 7524-7538, 2017
Mandates: Swiss National Science Foundation, UK Medical Research Council, European …
Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk
N Orr, A Lemnrau, R Cooke, O Fletcher, K Tomczyk, M Jones, N Johnson, ...
Nature genetics 44 (11), 1182-1184, 2012
Mandates: US National Institutes of Health, National Health and Medical Research …
An In Vivo Functional Screen Identifies ST6GalNAc2 Sialyltransferase as a Breast Cancer Metastasis Suppressor
N Murugaesu, M Iravani, A Van Weverwijk, A Ivetic, DA Johnson, ...
Cancer discovery 4 (3), 304-317, 2014
Mandates: UK Biotechnology and Biological Sciences Research Council, British Heart …
Deconvolution of Buparlisib’s mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention
T Bohnacker, AE Prota, F Beaufils, JE Burke, A Melone, AJ Inglis, ...
Nature communications 8 (1), 14683, 2017
Mandates: Swiss National Science Foundation, British Heart Foundation, UK Medical …
The transcription factor Erg regulates expression of histone deacetylase 6 and multiple pathways involved in endothelial cell migration and angiogenesis
GM Birdsey, NH Dryden, AV Shah, R Hannah, MD Hall, DO Haskard, ...
Blood, The Journal of the American Society of Hematology 119 (3), 894-903, 2012
Mandates: British Heart Foundation, Cancer Research UK
Discovery and Preclinical Characterization of 5-[4, 6-Bis ({3-oxa-8-azabicyclo [3.2. 1] octan-8-yl})-1, 3, 5-triazin-2-yl]-4-(difluoromethyl) pyridin-2-amine (PQR620), a Highly …
D Rageot, T Bohnacker, A Melone, JB Langlois, C Borsari, P Hillmann, ...
Journal of medicinal chemistry 61 (22), 10084-10105, 2018
Mandates: Swiss National Science Foundation, European Commission
Chemical development of intracellular protein heterodimerizers
D Erhart, M Zimmermann, O Jacques, MB Wittwer, B Ernst, E Constable, ...
Chemistry & biology 20 (4), 549-557, 2013
Mandates: Swiss National Science Foundation
In vitro and in vivo characterization of molecular interactions between calmodulin, ezrin/radixin/moesin, and L-selectin
DJ Killock, M Parsons, M Zarrouk, SM Ameer-Beg, AJ Ridley, DO Haskard, ...
Journal of Biological Chemistry 284 (13), 8833-8845, 2009
Mandates: US National Institutes of Health, British Heart Foundation
Effect of aromatase inhibition on functional gene modules in estrogen receptor–positive breast cancer and their relationship with antiproliferative response
Q Gao, N Patani, AK Dunbier, Z Ghazoui, M Zvelebil, LA Martin, ...
Clinical cancer research 20 (9), 2485-2494, 2014
Mandates: UK Medical Research Council, National Institute for Health Research, UK
Genomic characterisation of acral melanoma cell lines
SJ Furney, S Turajlic, K Fenwick, MB Lambros, A MacKay, G Ricken, ...
Pigment Cell & Melanoma Research 25 (4), 488-492, 2012
Mandates: Cancer Research UK
Mouse mammary stem cells express prognostic markers for triple-negative breast cancer
KJ Soady, H Kendrick, Q Gao, A Tutt, M Zvelebil, LD Ordonez, J Quist, ...
Breast Cancer Research 17, 1-23, 2015
Mandates: Breast Cancer Now, UK, Cancer Research UK, UK Medical Research Council …
CYP3A Variation, Premenopausal Estrone Levels, and Breast Cancer Risk
N Johnson, K Walker, LJ Gibson, N Orr, E Folkerd, B Haynes, C Palles, ...
Journal of the National Cancer Institute 104 (9), 657-669, 2012
Mandates: US National Institutes of Health, Cancer Research UK
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