Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes KF Petersen, S Dufour, D Befroy, R Garcia, GI Shulman New England Journal of Medicine 350 (7), 664-671, 2004 | 2699 | 2004 |
Mitochondrial dysfunction in the elderly: possible role in insulin resistance KF Petersen, D Befroy, S Dufour, J Dziura, C Ariyan, DL Rothman, ... Science 300 (5622), 1140-1142, 2003 | 2598 | 2003 |
Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease VT Samuel, ZX Liu, X Qu, BD Elder, S Bilz, D Befroy, AJ Romanelli, ... Journal of Biological Chemistry 279 (31), 32345-32353, 2004 | 1730 | 2004 |
Reversal of nonalcoholic hepatic steatosis, hepatic insulin resistance, and hyperglycemia by moderate weight reduction in patients with type 2 diabetes KF Petersen, S Dufour, D Befroy, M Lehrke, RE Hendler, GI Shulman Diabetes 54 (3), 603-608, 2005 | 1124 | 2005 |
Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents K Morino, KF Petersen, S Dufour, D Befroy, J Frattini, N Shatzkes, ... The Journal of clinical investigation 115 (12), 3587-3593, 2005 | 1039 | 2005 |
Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy KF Petersen, EA Oral, S Dufour, D Befroy, C Ariyan, C Yu, GW Cline, ... The Journal of clinical investigation 109 (10), 1345-1350, 2002 | 988 | 2002 |
The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome KF Petersen, S Dufour, DB Savage, S Bilz, G Solomon, S Yonemitsu, ... Proceedings of the National Academy of Sciences 104 (31), 12587-12594, 2007 | 905 | 2007 |
The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes AB Mayerson, RS Hundal, S Dufour, V Lebon, D Befroy, GW Cline, ... Diabetes 51 (3), 797-802, 2002 | 804 | 2002 |
Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis RM Reznick, H Zong, J Li, K Morino, IK Moore, JY Hannah, ZX Liu, J Dong, ... Cell metabolism 5 (2), 151-156, 2007 | 611 | 2007 |
Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients DE Befroy, KF Petersen, S Dufour, GF Mason, RA de Graaf, DL Rothman, ... Diabetes 56 (5), 1376-1381, 2007 | 533 | 2007 |
Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian-Indian men KF Petersen, S Dufour, J Feng, D Befroy, J Dziura, CD Man, C Cobelli, ... Proceedings of the National Academy of Sciences 103 (48), 18273-18277, 2006 | 480 | 2006 |
Paradoxical effects of increased expression of PGC-1α on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism CS Choi, DE Befroy, R Codella, S Kim, RM Reznick, YJ Hwang, ZX Liu, ... Proceedings of the National Academy of Sciences 105 (50), 19926-19931, 2008 | 325 | 2008 |
Comparative MR study of hepatic fat quantification using single‐voxel proton spectroscopy, two‐point dixon and three‐point IDEAL H Kim, SE Taksali, S Dufour, D Befroy, TR Goodman, KF Petersen, ... Magnetic Resonance in Medicine: An Official Journal of the International …, 2008 | 264 | 2008 |
Age-related changes in ATP-producing pathways in human skeletal muscle in vivo IR Lanza, DE Befroy, JA Kent-Braun Journal of applied physiology 99 (5), 1736-1744, 2005 | 219 | 2005 |
Increased substrate oxidation and mitochondrial uncoupling in skeletal muscle of endurance-trained individuals DE Befroy, KF Petersen, S Dufour, GF Mason, DL Rothman, GI Shulman Proceedings of the National Academy of Sciences 105 (43), 16701-16706, 2008 | 146 | 2008 |
A randomized controlled study of effects of dietary magnesium oxide supplementation on bone mineral content in healthy girls TO Carpenter, MC DeLucia, JH Zhang, G Bejnerowicz, L Tartamella, ... The Journal of Clinical Endocrinology & Metabolism 91 (12), 4866-4872, 2006 | 134 | 2006 |
In vivo ATP production during free‐flow and ischaemic muscle contractions in humans IR Lanza, DM Wigmore, DE Befroy, JA Kent‐Braun The Journal of physiology 577 (1), 353-367, 2006 | 124 | 2006 |
Resistance to thyroid hormone is associated with raised energy expenditure, muscle mitochondrial uncoupling, and hyperphagia CS Mitchell, DB Savage, S Dufour, N Schoenmakers, P Murgatroyd, ... The Journal of clinical investigation 120 (4), 1345-1354, 2010 | 123 | 2010 |
Direct assessment of hepatic mitochondrial oxidative and anaplerotic fluxes in humans using dynamic 13C magnetic resonance spectroscopy DE Befroy, RJ Perry, N Jain, S Dufour, GW Cline, JK Trimmer, J Brosnan, ... Nature medicine 20 (1), 98-102, 2014 | 101 | 2014 |
Hypophosphatemia promotes lower rates of muscle ATP synthesis DH Pesta, DN Tsirigotis, DE Befroy, D Caballero, MJ Jurczak, Y Rahimi, ... The FASEB Journal 30 (10), 3378, 2016 | 98 | 2016 |