Synthesis and anticonvulsant activity of new N-1′, N-3′-disubstituted-2′ H, 3H, 5′ H-spiro-(2-benzofuran-1, 4′-imidazolidine)-2′, 3, 5′-triones HJ Patel, J Sarra, F Caruso, M Rossi, U Doshi, RA Stephani Bioorganic & medicinal chemistry letters 16 (17), 4644-4647, 2006 | 63 | 2006 |
Human enterocytes as an in vitro model for the evaluation of intestinal drug metabolism: characterization of drug-metabolizing enzyme activities of cryopreserved human … MCD Ho, N Ring, K Amaral, U Doshi, AP Li Drug metabolism and disposition 45 (6), 686-691, 2017 | 60 | 2017 |
Evaluation of multiple mechanism-based toxicity endpoints in primary cultured human hepatocytes for the identification of drugs with clinical hepatotoxicity: Results from 152 … J Zhang, U Doshi, A Suzuki, CW Chang, J Borlak, AP Li, W Tong Chemico-biological interactions 255, 3-11, 2016 | 47 | 2016 |
Luciferin IPA–based higher throughput human hepatocyte screening assays for CYP3A4 inhibition and induction U Doshi, AP Li Journal of biomolecular screening 16 (8), 903-909, 2011 | 36 | 2011 |
A lower impact of an acute exposure to electronic cigarette aerosols than to cigarette smoke in human organotypic buccal and small airway cultures was demonstrated using … AR Iskandar, F Zanetti, A Kondylis, F Martin, P Leroy, S Majeed, S Steiner, ... Internal and Emergency Medicine 14, 863-883, 2019 | 34 | 2019 |
Effects of culture duration on gene expression of P450 isoforms, uptake and efflux transporters in primary hepatocytes cultured in the absence and presence of interleukin-6 … Q Yang, U Doshi, N Li, A P Li Current drug metabolism 13 (7), 938-946, 2012 | 32 | 2012 |
Endoplasmic reticulum stress induction and ERK1/2 activation contribute to nefazodone-induced toxicity in hepatic cells Z Ren, S Chen, J Zhang, U Doshi, AP Li, L Guo Toxicological Sciences 154 (2), 368-380, 2016 | 29 | 2016 |
Prediction of the pharmacokinetics of pravastatin as an OATP substrate using plateable human hepatocytes with human plasma data and PBPK modeling J Mao, U Doshi, M Wright, CECA Hop, AP Li, Y Chen CPT: Pharmacometrics & Systems Pharmacology 7 (4), 251-258, 2018 | 28 | 2018 |
In vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuries D Utkarsh, C Loretz, AP Li Chemico-Biological Interactions 255, 12-22, 2016 | 25 | 2016 |
Higher throughput human hepatocyte assays for the evaluation of time-dependent inhibition of CYP3A4 A P Li, U Doshi Drug Metabolism Letters 5 (3), 183-191, 2011 | 25 | 2011 |
Utility of pooled cryopreserved human enterocytes as an in vitro model for assessing intestinal clearance and drug-drug interactions S Wong, U Doshi, P Vuong, N Liu, S Tay, H Le, M Kosaka, JR Kenny, ... Drug Metabolism Letters 12 (1), 3-13, 2018 | 17 | 2018 |
Cytokine modulators in asthma: clinical perspectives U DOSHI, P SALAT, V PARIKH Indian journal of pharmacology 34 (1), 16-25, 2002 | 17 | 2002 |
A novel plated hepatocyte relay assay (PHRA) for in vitro evaluation of hepatic metabolic clearance of slowly metabolized compounds CC Peng, U Doshi, C Prakash, A P Li Drug metabolism letters 10 (1), 3-15, 2016 | 9 | 2016 |
Culture duration-, donor-, and medium-dependent changes in OATP1B3-mediated telmisartan uptake in human hepatocytes Q Zhu, H Xia, C Q Xia, Q Yang, U Doshi, A P Li, M Liao Drug metabolism letters 7 (2), 117-125, 2013 | 9 | 2013 |
Workshop Series to Identify, Discuss, and Develop Recommendations for the Optimal Generation and Use of In Vitro Assay Data for Tobacco Product Evaluation … MM Moore, J Clements, P Desai, U Doshi, M Gaca, X Guo, T Hashizume, ... Applied in vitro Toxicology 6 (2), 49-63, 2020 | 7 | 2020 |
Fit-for-purpose characterization of air-liquid-interface (ALI) in vitro exposure systems for e-vapor aerosol J Zhang, U Doshi, RL Wolz, P Kosachevsky, MJ Oldham, IG Gillman, ... Toxicology in Vitro 82, 105352, 2022 | 5 | 2022 |
In vitro evaluation of the metabolic stability of nine fragrance chemicals in trout and human hepatocytes J Weeks, AP Li, U Doshi, K Johanning, PD Guiney Journal of Applied Toxicology 40 (10), 1421-1434, 2020 | 5 | 2020 |
Integrated discrete multiple organ co-culture (IdMOC) system for the evaluation of multiple organ drug distribution, drug metabolism, and organ specific drug toxicity AP Li, A Uzgare, H Saminathan, U Doshi Drug metabolism reviews, 69-77, 2011 | 2 | 2011 |
Characterization of an air-liquid-interface (ALI) in vitro exposure system for e-vapor product J Zhang, M Oldham, R Wolz, P Kosachevsky, U Doshi, I Gilman, KM Lee 58th Society of Toxicology, Baltimore, MD, 2019 | 1 | 2019 |
Isolation and cryopreservation of enterocytes for metabolism and uptake studies AP Li, C Loretz, Q Yang, U Doshi DRUG METABOLISM REVIEWS 48, 93-93, 2016 | 1 | 2016 |