| Three-dimensional structure of recombinant human interferon-γ SE Ealick, WJ Cook, S Vijay-Kumar, M Carson, TL Nagabhushan, ... Science 252 (5006), 698-702, 1991 | 619 | 1991 |
| The structural and biochemical foundations of thiamin biosynthesis CT Jurgenson, TP Begley, SE Ealick Annual review of biochemistry 78 (1), 569-603, 2009 | 371 | 2009 |
| Thiamin biosynthesis in prokaryotes TP Begley, DM Downs, SE Ealick, FW McLafferty, APGM Van Loon, ... Archives of microbiology 171, 293-300, 1999 | 367 | 1999 |
| Flavogenomics–a genomic and structural view of flavin‐dependent proteins P Macheroux, B Kappes, SE Ealick The FEBS journal 278 (15), 2625-2634, 2011 | 364 | 2011 |
| Structural analyses reveal two distinct families of nucleoside phosphorylases MJ Pugmire, SE Ealick Biochemical Journal 361 (1), 1-25, 2002 | 307 | 2002 |
| Structural biology of the purine biosynthetic pathway Y Zhang, M Morar, SE Ealick Cellular and molecular life sciences 65, 3699-3724, 2008 | 267 | 2008 |
| Three-dimensional structure of human erythrocytic purine nucleoside phosphorylase at 3.2 A resolution. SE Ealick, SA Rule, DC Carter, TJ Greenhough, YS Babu, WJ Cook, ... Journal of Biological Chemistry 265 (3), 1812-1820, 1990 | 252 | 1990 |
| Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors. SE Ealick, YS Babu, CE Bugg, MD Erion, WC Guida, JA Montgomery, ... Proceedings of the National Academy of Sciences 88 (24), 11540-11544, 1991 | 238 | 1991 |
| Protein crystal growth in microgravity LJ DeLucas, CD Smith, HW Smith, S Vijay-Kumar, SE Senadhi, SE Ealick, ... Science 246 (4930), 651-654, 1989 | 234 | 1989 |
| Structure of Human Adenosine Kinase at 1.5 Å Resolution, II Mathews, MD Erion, SE Ealick Biochemistry 37 (45), 15607-15620, 1998 | 232 | 1998 |
| The crystal structure and mechanism of orotidine 5′-monophosphate decarboxylase TC Appleby, C Kinsland, TP Begley, SE Ealick Proceedings of the National Academy of Sciences 97 (5), 2005-2010, 2000 | 230 | 2000 |
| Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor MR Walter, WJ Cook, SE Ealick, TL Nagabhushan, PP Trotta, CE Bugg Journal of molecular biology 224 (4), 1075-1085, 1992 | 207 | 1992 |
| Diphthamide biosynthesis requires an organic radical generated by an iron–sulphur enzyme Y Zhang, X Zhu, AT Torelli, M Lee, B Dzikovski, RM Koralewski, E Wang, ... Nature 465 (7300), 891-896, 2010 | 206 | 2010 |
| Structure of Oxalate Decarboxylase from Bacillus subtilis at 1.75 Å Resolution, R Anand, PC Dorrestein, C Kinsland, TP Begley, SE Ealick Biochemistry 41 (24), 7659-7669, 2002 | 195 | 2002 |
| Crystal structure of recombinant human interleukin-4. MR Walter, WJ Cook, BG Zhao, RP Cameron Jr, SE Ealick, RL Walter Jr, ... Journal of Biological Chemistry 267 (28), 20371-20376, 1992 | 186 | 1992 |
| Purine nucleoside phosphorylase. 2. Catalytic mechanism MD Erion, JD Stoeckler, WC Guida, RL Walter, SE Ealick Biochemistry 36 (39), 11735-11748, 1997 | 184 | 1997 |
| Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily A Chatterjee, Y Li, Y Zhang, TL Grove, M Lee, C Krebs, SJ Booker, ... Nature chemical biology 4 (12), 758-765, 2008 | 181 | 2008 |
| Saccharomyces cerevisiae THI4p is a suicide thiamine thiazole synthase A Chatterjee, ND Abeydeera, S Bale, PJ Pai, PC Dorrestein, DH Russell, ... Nature 478 (7370), 542-546, 2011 | 178 | 2011 |
| The crystal structure of Escherichia coli purine nucleoside phosphorylase: a comparison with the human enzyme reveals a conserved topology C Mao, WJ Cook, M Zhou, GW Koszalka, TA Krenitsky, SE Ealick Structure 5 (10), 1373-1383, 1997 | 175 | 1997 |
| Structure-based design of inhibitors of purine nucleoside phosphorylase. 1. 9-(arylmethyl) derivatives of 9-deazaguanine JA Montgomery, S Niwas, JD Rose, JA Secrist III, YS Babu, CE Bugg, ... Journal of medicinal chemistry 36 (1), 55-69, 1993 | 169 | 1993 |
