Versican V1 proteolysis in human aorta in vivo occurs at the Glu441-Ala442 bond, a site that is cleaved by recombinant ADAMTS-1 and ADAMTS-4 JD Sandy, J Westling, RD Kenagy, ML Iruela-Arispe, C Verscharen, ... Journal of Biological Chemistry 276 (16), 13372-13378, 2001 | 525 | 2001 |
Matrix metalloproteinase-9 overexpression enhances vascular smooth muscle cell migration and alters remodeling in the injured rat carotid artery DP Mason, RD Kenagy, D Hasenstab, DF Bowen-Pope, RA Seifert, ... Circulation research 85 (12), 1179-1185, 1999 | 431 | 1999 |
Regulation of vascular smooth muscle cell migration and proliferation in vitro and in injured rat arteries by a synthetic matrix metalloproteinase inhibitor N Zempo, N Koyama, RD Kenagy, HJ Lea, AW Clowes Arteriosclerosis, thrombosis, and vascular biology 16 (1), 28-33, 1996 | 399 | 1996 |
Matrix metalloproteinases of vascular wall cells are increased in balloon-injured rat carotid artery N Zempo, RD Kenagy, YPT Au, M Bendeck, MM Clowes, MA Reidy, ... Journal of vascular surgery 20 (2), 209-217, 1994 | 361 | 1994 |
Primate smooth muscle cell migration from aortic explants is mediated by endogenous platelet-derived growth factor and basic fibroblast growth factor acting through matrix … RD Kenagy, CE Hart, WG Stetler-Stevenson, AW Clowes Circulation 96 (10), 3555-3560, 1997 | 187 | 1997 |
Prevention of aneurysm development and rupture by local overexpression of plasminogen activator inhibitor-1 E Allaire, D Hasenstab, RD Kenagy, B Starcher, MM Clowes, AW Clowes Circulation 98 (3), 249-255, 1998 | 177 | 1998 |
PDGFβ receptor blockade inhibits intimal hyperplasia in the baboon CE Hart, LW Kraiss, S Vergel, D Gilbertson, R Kenagy, T Kirkman, ... Circulation 99 (4), 564-569, 1999 | 159 | 1999 |
Platelet-derived growth factor–BB transactivates the fibroblast growth factor receptor to induce proliferation in human smooth muscle cells E Millette, BH Rauch, RD Kenagy, G Daum, AW Clowes Trends in cardiovascular medicine 16 (1), 25-28, 2006 | 158 | 2006 |
The role of plasminogen, plasminogen activators, and matrix metalloproteinases in primate arterial smooth muscle cell migration RD Kenagy, S Vergel, E Mattsson, M Bendeck, MA Reidy, AW Clowes Arteriosclerosis, thrombosis, and vascular biology 16 (11), 1373-1382, 1996 | 154 | 1996 |
Heparin inhibits the induction of three matrix metalloproteinases (stromelysin, 92-kD gelatinase, and collagenase) in primate arterial smooth muscle cells. RD Kenagy, ST Nikkari, HG Welgus, AW Clowes The Journal of clinical investigation 93 (5), 1987-1993, 1994 | 147 | 1994 |
Platelet-derived growth Factor-BB–Induced Human smooth muscle cell proliferation depends on Basic FGF release and FGFR-1 activation E Millette, BH Rauch, O Defawe, RD Kenagy, G Daum, AW Clowes Circulation research 96 (2), 172-179, 2005 | 146 | 2005 |
Versican degradation and vascular disease RD Kenagy, AH Plaas, TN Wight Trends in cardiovascular medicine 16 (6), 209-215, 2006 | 118 | 2006 |
Mechanisms of inhibition by heparin of vascular smooth muscle cell proliferation and migration YPT Au, RD Kenagy, MM Clowes, AW Clowes Haemostasis 23, 177-177, 1993 | 112 | 1993 |
Thrombin-and factor Xa–induced DNA synthesis is mediated by transactivation of fibroblast growth factor receptor-1 in human vascular smooth muscle cells BH Rauch, E Millette, RD Kenagy, G Daum, AW Clowes Circulation research 94 (3), 340-345, 2004 | 107 | 2004 |
Heparin inhibits the expression of tissue-type plasminogen activator by smooth muscle cells in injured rat carotid artery. AW Clowes, MM Clowes, TR Kirkman, CL Jackson, YP Au, R Kenagy Circulation research 70 (6), 1128-1136, 1992 | 102 | 1992 |
Heparin selectively inhibits the transcription of tissue-type plasminogen activator in primate arterial smooth muscle cells during mitogenesis. YP Au, RD Kenagy, AW Clowes Journal of Biological Chemistry 267 (5), 3438-3444, 1992 | 100 | 1992 |
Activation of metalloproteinases and their association with integrins: an auxiliary apoptotic pathway in human endothelial cells. B Levkau, RD Kenagy, A Karsan, B Weitkamp, AW Clowes, R Ross, ... Cell death and differentiation 9 (12), 1360-1367, 2002 | 84 | 2002 |
Syndecan-4 is required for thrombin-induced migration and proliferation in human vascular smooth muscle cells BH Rauch, E Millette, RD Kenagy, G Daum, JW Fischer, AW Clowes Journal of Biological Chemistry 280 (17), 17507-17511, 2005 | 81 | 2005 |
Increased plasmin and serine proteinase activity during flow-induced intimal atrophy in baboon PTFE grafts RD Kenagy, JW Fischer, MG Davies, SA Berceli, SM Hawkins, TN Wight, ... Arteriosclerosis, thrombosis, and vascular biology 22 (3), 400-404, 2002 | 73 | 2002 |
MMP9 production by human monocyte-derived macrophages is decreased on polymerized type I collagen S Lepidi, RD Kenagy, EW Raines, ES Chiu, A Chait, R Ross, AW Clowes Journal of vascular surgery 34 (6), 1111-1118, 2001 | 72 | 2001 |