Specific targeting of acetylcholinesterase and butyrylcholinesterase recognition sites. Rational design of novel, selective, and highly potent cholinesterase inhibitors L Savini, A Gaeta, C Fattorusso, B Catalanotti, G Campiani, L Chiasserini, ... Journal of Medicinal Chemistry 46 (1), 1-4, 2003 | 185 | 2003 |
Non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors: past, present, and future perspectives G Campiani, A Ramunno, G Maga, V Nacci, C Fattorusso, B Catalanotti, ... Current pharmaceutical design 8 (8), 615-657, 2002 | 163 | 2002 |
Synthesis and Pharmacological Evaluation of Potent and Highly Selective D3 Receptor Ligands: Inhibition of Cocaine-Seeking Behavior and the Role of Dopamine D3/D … G Campiani, S Butini, F Trotta, C Fattorusso, B Catalanotti, F Aiello, ... Journal of medicinal chemistry 46 (18), 3822-3839, 2003 | 115 | 2003 |
Hijacking SARS-CoV-2/ACE2 receptor interaction by natural and semi-synthetic steroidal agents acting on functional pockets on the receptor binding domain A Carino, F Moraca, B Fiorillo, S Marchianò, V Sepe, M Biagioli, ... Frontiers in Chemistry 8, 572885, 2020 | 107 | 2020 |
Development of molecular probes for the identification of extra interaction sites in the mid-gorge and peripheral sites of butyrylcholinesterase (BuChE). Rational design of … G Campiani, C Fattorusso, S Butini, A Gaeta, M Agnusdei, S Gemma, ... Journal of medicinal chemistry 48 (6), 1919-1929, 2005 | 90 | 2005 |
Endoperoxide derivatives from marine organisms: 1, 2-dioxanes of the plakortin family as novel antimalarial agents C Fattorusso, G Campiani, B Catalanotti, M Persico, N Basilico, S Parapini, ... Journal of medicinal chemistry 49 (24), 7088-7094, 2006 | 80 | 2006 |
Pyrrolo [1, 3] benzothiazepine-based serotonin and dopamine receptor antagonists. Molecular modeling, further structure− activity relationship studies, and identification of … G Campiani, S Butini, C Fattorusso, B Catalanotti, S Gemma, V Nacci, ... Journal of medicinal chemistry 47 (1), 143-157, 2004 | 79 | 2004 |
Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors S Butini, G Campiani, M Borriello, S Gemma, A Panico, M Persico, ... Journal of medicinal chemistry 51 (11), 3154-3170, 2008 | 69 | 2008 |
Neuronal high-affinity sodium-dependent glutamate transporters (EAATs): targets for the development of novel therapeutics against neurodegenerative diseases G Campiani, C Fattorusso, M Angelis, B Catalanotti, S Butini, R Fattorusso, ... Current pharmaceutical design 9 (8), 599-625, 2003 | 68 | 2003 |
A rational approach to the design of selective substrates and potent nontransportable inhibitors of the excitatory amino acid transporter EAAC1 (EAAT3). New glutamate and … G Campiani, M De Angelis, S Armaroli, C Fattorusso, B Catalanotti, ... Journal of medicinal chemistry 44 (16), 2507-2510, 2001 | 65 | 2001 |
Discovery of Huperzine A− Tacrine Hybrids as Potent Inhibitors of Human Cholinesterases Targeting Their Midgorge Recognition Sites S Gemma, E Gabellieri, P Huleatt, C Fattorusso, M Borriello, B Catalanotti, ... Journal of medicinal chemistry 49 (11), 3421-3425, 2006 | 63 | 2006 |
Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad … C Fattorusso, S Gemma, S Butini, P Huleatt, B Catalanotti, M Persico, ... Journal of medicinal chemistry 48 (23), 7153-7165, 2005 | 61 | 2005 |
Benzoxepin-derived estrogen receptor modulators: a novel molecular scaffold for the estrogen receptor DG Lloyd, RB Hughes, DM Zisterer, DC Williams, C Fattorusso, ... Journal of medicinal chemistry 47 (23), 5612-5615, 2004 | 58 | 2004 |
Exploitation of a very small peptide nucleic acid as a new inhibitor of miR‐509‐3p involved in the regulation of cystic fibrosis disease‐gene expression F Amato, R Tomaiuolo, F Nici, N Borbone, A Elce, B Catalanotti, ... BioMed research international 2014 (1), 610718, 2014 | 54 | 2014 |
Pyrrolo [1, 5] benzoxa (thia) zepines as a new class of potent apoptotic agents. Biological studies and identification of an intracellular location of their drug target MM Mc Gee, S Gemma, S Butini, A Ramunno, DM Zisterer, C Fattorusso, ... Journal of medicinal chemistry 48 (13), 4367-4377, 2005 | 54 | 2005 |
Design and synthesis of potent antimalarial agents based on clotrimazole scaffold: exploring an innovative pharmacophore S Gemma, G Campiani, S Butini, G Kukreja, BP Joshi, M Persico, ... Journal of medicinal chemistry 50 (4), 595-598, 2007 | 50 | 2007 |
Pyrrolo [1, 3] benzothiazepine-based atypical antipsychotic agents. Synthesis, structure− activity relationship, molecular modeling, and biological studies G Campiani, S Butini, S Gemma, V Nacci, C Fattorusso, B Catalanotti, ... Journal of medicinal chemistry 45 (2), 344-359, 2002 | 49 | 2002 |
Novel atypical antipsychotic agents: rational design, an efficient palladium-catalyzed route, and pharmacological studies G Campiani, S Butini, C Fattorusso, F Trotta, S Gemma, B Catalanotti, ... Journal of medicinal chemistry 48 (6), 1705-1708, 2005 | 47 | 2005 |
Specific Targeting of Peripheral Serotonin 5-HT3 Receptors. Synthesis, Biological Investigation, and Structure−Activity Relationships E Morelli, S Gemma, R Budriesi, G Campiani, E Novellino, C Fattorusso, ... Journal of medicinal chemistry 52 (11), 3548-3562, 2009 | 46 | 2009 |
Insight into the mechanism of action of plakortins, simple 1, 2-dioxane antimalarials O Taglialatela-Scafati, E Fattorusso, A Romano, F Scala, V Barone, ... Organic & Biomolecular Chemistry 8 (4), 846-856, 2010 | 45 | 2010 |