Articles with public access mandates - Dina RobaaLearn more
Not available anywhere: 21
Chemically induced degradation of sirtuin 2 (Sirt2) by a proteolysis targeting chimera (PROTAC) based on sirtuin rearranging ligands (SirReals)
M Schiedel, D Herp, S Hammelmann, S Swyter, A Lehotzky, D Robaa, ...
Journal of medicinal chemistry 61 (2), 482-491, 2018
Mandates: German Research Foundation, Hungarian Scientific Research Fund, European …
The Current State of NAD+‐Dependent Histone Deacetylases (Sirtuins) as Novel Therapeutic Targets
M Schiedel, D Robaa, T Rumpf, W Sippl, M Jung
Medicinal research reviews 38 (1), 147-200, 2018
Mandates: European Commission
Lysine deacetylase inhibitors in parasites: past, present, and future perspectives
GS Hailu, D Robaa, M Forgione, W Sippl, D Rotili, A Mai
Journal of Medicinal Chemistry 60 (12), 4780-4804, 2017
Mandates: Fondazione Cariplo, European Commission, Government of Italy
Strategies to design selective histone deacetylase inhibitors
J Melesina, CV Simoben, L Praetorius, EF Bülbül, D Robaa, W Sippl
ChemMedChem 16 (9), 1336-1359, 2021
Mandates: German Research Foundation
Mind the methyl: methyllysine binding proteins in epigenetic regulation
T Wagner, D Robaa, W Sippl, M Jung
ChemMedChem 9 (3), 466-483, 2014
Mandates: German Research Foundation
Homology modeling of parasite histone deacetylases to guide the structure-based design of selective inhibitors
J Melesina, D Robaa, RJ Pierce, C Romier, W Sippl
Journal of Molecular Graphics and Modelling 62, 342-361, 2015
Mandates: National Institute of Health and Medical Research, France
Structure-activity studies on N-Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic …
J Schulz-Fincke, M Hau, J Barth, D Robaa, D Willmann, A Kürner, J Haas, ...
European Journal of Medicinal Chemistry 144, 52-67, 2018
Mandates: German Research Foundation, European Commission
Enantiomerically Pure 2-Methyltetrahydro-3-benzazepin-1-ols Selectively Blocking GluN2B Subunit Containing N-Methyl-d-aspartate Receptors
B Tewes, B Frehland, D Schepmann, D Robaa, T Uengwetwanit, F Gaube, ...
Journal of Medicinal Chemistry 58 (15), 6293-6305, 2015
Mandates: German Research Foundation
Identification and structure–activity relationship studies of small‐molecule inhibitors of the methyllysine reader protein Spindlin1
D Robaa, T Wagner, C Luise, L Carlino, J McMillan, R Flaig, R Schüle, ...
ChemMedChem 11 (20), 2327-2338, 2016
Mandates: German Research Foundation, European Commission
A facile synthesis of ligands for the von Hippel–Lindau E3 ligase
C Steinebach, SA Voell, LP Vu, A Bricelj, I Sosič, G Schnakenburg, ...
Synthesis 52 (17), 2521-2527, 2020
Mandates: Slovenian Research Agency
Design, synthesis, pharmacological evaluation and docking studies of GluN2B‐selective NMDA receptor antagonists with a benzo [7] annulen‐7‐amine scaffold
S Gawaskar, L Temme, JA Schreiber, D Schepmann, A Bonifazi, D Robaa, ...
ChemMedChem 12 (15), 1212-1222, 2017
Mandates: German Research Foundation
Hydroxymethyl bioisosteres of phenolic GluN2B-selective NMDA receptor antagonists: Design, synthesis and pharmacological evaluation
L Temme, B Frehland, D Schepmann, D Robaa, W Sippl, B Wünsch
European Journal of Medicinal Chemistry 144, 672-681, 2018
Mandates: German Research Foundation
Peptide backbone conformation affects the substrate preference of protein arginine methyltransferase I
K Kölbel, C Ihling, U Kühn, I Neundorf, S Otto, J Stichel, D Robaa, ...
Biochemistry 51 (27), 5463-5475, 2012
Mandates: German Research Foundation
Negative allosteric modulators of the GluN2B NMDA receptor with phenylethylamine structure embedded in ring-expanded and ring-contracted scaffolds
L Temme, E Bechthold, JA Schreiber, S Gawaskar, D Schepmann, ...
European Journal of Medicinal Chemistry 190, 112138, 2020
Mandates: German Research Foundation
Discovery of histone demethylase inhibitors
AT Hauser, M Roatsch, J Schulz-Fincke, D Robaa, W Sippl, M Jung
Epigenetic Technological Applications, 397-424, 2015
Mandates: German Research Foundation
Opening the selectivity pocket in the human lysine deacetylase Sirtuin2–new opportunities, new questions
D Robaa, D Monaldi, N Wössner, N Kudo, T Rumpf, M Schiedel, ...
The Chemical Record 18 (12), 1701-1707, 2018
Mandates: German Research Foundation
Impact of hydroxy moieties at the benzo [7] annulene ring system of GluN2B ligands: Design, synthesis and biological evaluation
L Temme, F Boergel, D Schepmann, D Robaa, W Sippl, C Daniliuc, ...
Bioorganic & Medicinal Chemistry 27 (23), 115146, 2019
Mandates: German Research Foundation
Chemically Diverse S. mansoni HDAC8 Inhibitors Reduce Viability in Worm Larval and Adult Stages
B Noce, E Di Bello, C Zwergel, R Fioravanti, S Valente, D Rotili, A Masotti, ...
ChemMedChem 18 (3), e202200510, 2023
Mandates: Swiss National Science Foundation
Stereospecific capillary electrophoresis assays using pentapeptide substrates for the study of Aspergillus nidulans methionine sulfoxide reductase A and mutant …
Q Zhu, RG El‐Mergawy, Y Zhou, C Chen, SH Heinemann, R Schönherr, ...
Electrophoresis 37 (14), 2083-2090, 2016
Mandates: German Research Foundation
Epigenetic Readers Interpreting the Lysine Methylome—Biological Roles and Drug Discovery
T Wagner, D Robaa, W Sippl, M Jung
Drug Discovery in Cancer Epigenetics, 273-304, 2016
Mandates: German Research Foundation
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