| The shock of aging: molecular chaperones and the heat shock response in longevity and aging–a mini-review SK Calderwood, A Murshid, T Prince Gerontology 55 (5), 550-558, 2009 | 437 | 2009 |
| Regulation and function of the human HSP90AA1 gene AD Zuehlke, K Beebe, L Neckers, T Prince Gene 570 (1), 8-16, 2015 | 260 | 2015 |
| mTOR is essential for the proteotoxic stress response, HSF1 activation and heat shock protein synthesis SD Chou, T Prince, J Gong, SK Calderwood PloS one 7 (6), e39679, 2012 | 246 | 2012 |
| Targeting the oncogene and kinome chaperone CDC37 PJ Gray Jr, T Prince, J Cheng, MA Stevenson, SK Calderwood Nature Reviews Cancer 8 (7), 491-495, 2008 | 140 | 2008 |
| Asymmetric Hsp90 N domain SUMOylation recruits Aha1 and ATP-competitive inhibitors M Mollapour, D Bourboulia, K Beebe, MR Woodford, S Polier, A Hoang, ... Molecular cell 53 (2), 317-329, 2014 | 134 | 2014 |
| Phosphorylation of serine 13 is required for the proper function of the Hsp90 co-chaperone, Cdc37 J Shao, T Prince, SD Hartson, RL Matts Journal of biological chemistry 278 (40), 38117-38120, 2003 | 127 | 2003 |
| Signal transduction pathways leading to heat shock transcription SK Calderwood, Y Wang, X Xie, MA Khaleque, SD Chou, A Murshid, ... Signal transduction insights 2, STI. S3994, 2010 | 116 | 2010 |
| HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation T Kijima, TL Prince, ML Tigue, KH Yim, H Schwartz, K Beebe, S Lee, ... Scientific reports 8 (1), 6976, 2018 | 114 | 2018 |
| Protein kinase A binds and activates heat shock factor 1 A Murshid, SD Chou, T Prince, Y Zhang, A Bharti, SK Calderwood PloS one 5 (11), e13830, 2010 | 102 | 2010 |
| Englerin A stimulates PKCθ to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethality C Sourbier, BT Scroggins, R Ratnayake, TL Prince, S Lee, MJ Lee, ... Cancer cell 23 (2), 228-237, 2013 | 97 | 2013 |
| Heat shock proteins are essential components in transformation and tumor progression: cancer cell intrinsic pathways and beyond BJ Lang, ME Guerrero-Giménez, TL Prince, A Ackerman, C Bonorino, ... International journal of molecular sciences 20 (18), 4507, 2019 | 84 | 2019 |
| Definition of protein kinase sequence motifs that trigger high affinity binding of Hsp90 and Cdc37 T Prince, RL Matts Journal of Biological Chemistry 279 (38), 39975-39981, 2004 | 82 | 2004 |
| The functions and regulation of heat shock proteins; key orchestrators of proteostasis and the heat shock response BJ Lang, ME Guerrero, TL Prince, Y Okusha, C Bonorino, SK Calderwood Archives of toxicology 95 (6), 1943-1970, 2021 | 81 | 2021 |
| Activation of Hsp90 enzymatic activity and conformational dynamics through rationally designed allosteric ligands S Sattin, J Tao, G Vettoretti, E Moroni, M Pennati, A Lopergolo, L Morelli, ... Chemistry–A European Journal 21 (39), 13598-13608, 2015 | 78 | 2015 |
| Role and regulation of myeloid zinc finger protein 1 in cancer T Eguchi, T Prince, B Wegiel, SK Calderwood Journal of cellular biochemistry 116 (10), 2146-2154, 2015 | 73 | 2015 |
| Cdk2: a genuine protein kinase client of Hsp90 and Cdc37 T Prince, L Sun, RL Matts Biochemistry 44 (46), 15287-15295, 2005 | 73 | 2005 |
| Application of urinary volatile organic compounds (VOCs) for the diagnosis of prostate cancer Q Gao, X Su, MH Annabi, BR Schreiter, T Prince, A Ackerman, S Morgas, ... Clinical genitourinary cancer 17 (3), 183-190, 2019 | 67 | 2019 |
| Gambogic acid identifies an isoform-specific druggable pocket in the middle domain of Hsp90β KH Yim, TL Prince, S Qu, F Bai, PA Jennings, JN Onuchic, ... Proceedings of the National Academy of Sciences 113 (33), E4801-E4809, 2016 | 67 | 2016 |
| Client proteins and small molecule inhibitors display distinct binding preferences for constitutive and stress-induced HSP90 isoforms and their conformationally restricted mutants TL Prince, T Kijima, M Tatokoro, S Lee, S Tsutsumi, K Yim, C Rivas, ... PloS one 10 (10), e0141786, 2015 | 61 | 2015 |
| Scavenger receptor SREC-I mediated entry of TLR4 into lipid microdomains and triggered inflammatory cytokine release in RAW 264.7 cells upon LPS activation A Murshid, J Gong, T Prince, TJ Borges, SK Calderwood PLoS One 10 (4), e0122529, 2015 | 56 | 2015 |
