MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-β-induced collagen expression via inhibition of E-box repressors M Kato, J Zhang, M Wang, L Lanting, H Yuan, JJ Rossi, R Natarajan Proceedings of the National Academy of Sciences 104 (9), 3432-3437, 2007 | 899 | 2007 |
TGF-β activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN M Kato, S Putta, M Wang, H Yuan, L Lanting, I Nair, A Gunn, Y Nakagawa, ... Nature cell biology 11 (7), 881-889, 2009 | 696 | 2009 |
High glucose-induced expression of proinflammatory cytokine and chemokine genes in monocytic cells N Shanmugam, MA Reddy, M Guha, R Natarajan Diabetes 52 (5), 1256-1264, 2003 | 689 | 2003 |
Epigenetic mechanisms in diabetic complications and metabolic memory MA Reddy, E Zhang, R Natarajan Diabetologia 58, 443-455, 2015 | 501 | 2015 |
Epigenetic histone H3 lysine 9 methylation in metabolic memory and inflammatory phenotype of vascular smooth muscle cells in diabetes LM Villeneuve, MA Reddy, LL Lanting, M Wang, L Meng, R Natarajan Proceedings of the National Academy of Sciences 105 (26), 9047-9052, 2008 | 467 | 2008 |
Magnesium deficiency produces insulin resistance and increased thromboxane synthesis. JL Nadler, T Buchanan, R Natarajan, I Antonipillai, R Bergman, R Rude Hypertension 21 (6_pt_2), 1024-1029, 1993 | 463 | 1993 |
The product of the CYP11B2 gene is required for aldosterone biosynthesis in the human adrenal cortex KM Curnow, MT Tusie-Luna, L Pascoe, R Natarajan, JL Gu, JL Nadler, ... Molecular Endocrinology 5 (10), 1513-1522, 1991 | 455 | 1991 |
Inhibiting microRNA-192 ameliorates renal fibrosis in diabetic nephropathy S Putta, L Lanting, G Sun, G Lawson, M Kato, R Natarajan Journal of the American Society of Nephrology 23 (3), 458-469, 2012 | 451 | 2012 |
In vivo chromatin remodeling events leading to inflammatory gene transcription under diabetic conditions F Miao, IG Gonzalo, L Lanting, R Natarajan Journal of Biological Chemistry 279 (17), 18091-18097, 2004 | 437 | 2004 |
Molecular mechanisms of tumor necrosis factor α gene expression in monocytic cells via hyperglycemia-induced oxidant stress-dependent and-independent pathways M Guha, W Bai, JL Nadler, R Natarajan Journal of Biological Chemistry 275 (23), 17728-17739, 2000 | 433 | 2000 |
Epigenetics and epigenomics in diabetic kidney disease and metabolic memory M Kato, R Natarajan Nature Reviews Nephrology 15 (6), 327-345, 2019 | 426 | 2019 |
Hyperglycemia-induced activation of nuclear transcription factor kappaB in vascular smooth muscle cells. KK Yerneni, W Bai, BV Khan, RM Medford, R Natarajan Diabetes 48 (4), 855-864, 1999 | 418 | 1999 |
Role of the histone H3 lysine 4 methyltransferase, SET7/9, in the regulation of NF-κB-dependent inflammatory genes: relevance to diabetes and inflammation Y Li, MA Reddy, F Miao, N Shanmugam, JK Yee, D Hawkins, B Ren, ... Journal of Biological Chemistry 283 (39), 26771-26781, 2008 | 387 | 2008 |
The role of epigenetics in the pathology of diabetic complications LM Villeneuve, R Natarajan American Journal of Physiology-Renal Physiology 299 (1), F14-F25, 2010 | 383 | 2010 |
Diabetes-induced accelerated atherosclerosis in swine RG Gerrity, R Natarajan, JL Nadler, T Kimsey Diabetes 50 (7), 1654-1665, 2001 | 350 | 2001 |
Diabetic nephropathy—emerging epigenetic mechanisms M Kato, R Natarajan Nature Reviews Nephrology 10 (9), 517-530, 2014 | 349 | 2014 |
Novel long noncoding RNAs are regulated by angiotensin II in vascular smooth muscle cells A Leung, C Trac, W Jin, L Lanting, A Akbany, P Sætrom, DE Schones, ... Circulation research 113 (3), 266-278, 2013 | 336 | 2013 |
Lipid inflammatory mediators in diabetic vascular disease R Natarajan, JL Nadler Arteriosclerosis, thrombosis, and vascular biology 24 (9), 1542-1548, 2004 | 295 | 2004 |
A microRNA circuit mediates transforming growth factor-β1 autoregulation in renal glomerular mesangial cells M Kato, L Arce, M Wang, S Putta, L Lanting, R Natarajan Kidney international 80 (4), 358-368, 2011 | 293 | 2011 |
Lymphocytes from patients with type 1 diabetes display a distinct profile of chromatin histone H3 lysine 9 dimethylation: an epigenetic study in diabetes F Miao, DD Smith, L Zhang, A Min, W Feng, R Natarajan Diabetes 57 (12), 3189-3198, 2008 | 283 | 2008 |