| AKT facilitates EGFR trafficking and degradation by phosphorylating and activating PIKfyve EE Er, MC Mendoza, AM Mackey, LE Rameh, J Blenis Science signaling 6 (279), ra45-ra45, 2013 | 116 | 2013 |
| Production of phosphatidylinositol 5‐phosphate via PIKfyve and MTMR3 regulates cell migration A Oppelt, VH Lobert, K Haglund, AM Mackey, LE Rameh, K Liestøl, ... EMBO reports 14 (1), 57-64, 2013 | 85 | 2013 |
| Redox survival signalling in retina-derived 661W cells AM Mackey, N Sanvicens, G Groeger, F Doonan, D Wallace, TG Cotter Cell Death & Differentiation 15 (8), 1291-1303, 2008 | 73 | 2008 |
| Stress‐induced activation of Nox contributes to cell survival signalling via production of hydrogen peroxide G Groeger, AM Mackey, CA Pettigrew, L Bhatt, TG Cotter Journal of neurochemistry 109 (5), 1544-1554, 2009 | 66 | 2009 |
| PIP4kγ is a substrate for mTORC1 that maintains basal mTORC1 signaling during starvation AM Mackey, DA Sarkes, I Bettencourt, JM Asara, LE Rameh Science signaling 7 (350), ra104-ra104, 2014 | 44 | 2014 |
| IGF‐I maintains calpastatin expression and attenuates apoptosis in several models of photoreceptor cell death AI Arroba, D Wallace, A Mackey, EJ De La Rosa, TG Cotter European Journal of Neuroscience 30 (6), 975-986, 2009 | 37 | 2009 |
| A proinflammatory function of toll-like receptor 2 in the retinal pigment epithelium as a novel target for reducing choroidal neovascularization in age-related macular degeneration L Feng, M Ju, KYV Lee, A Mackey, M Evangelista, D Iwata, P Adamson, ... The American journal of pathology 187 (10), 2208-2221, 2017 | 30 | 2017 |
| A stress survival response in retinal cells mediated through inhibition of the serine/threonine phosphatase PP2A S Finnegan, AM Mackey, TG Cotter European Journal of Neuroscience 32 (3), 322-334, 2010 | 22 | 2010 |
| Fibrotic changes and endothelial-to-mesenchymal transition promoted by VEGFR2 antagonism alter the therapeutic effects of VEGFA pathway blockage in a mouse model of choroidal … FA Rossato, Y Su, A Mackey, YSE Ng Cells 9 (9), 2057, 2020 | 19 | 2020 |
| IQGAP1 makes PI(3)K signalling as easy as PIP, PIP2, PIP3 LE Rameh, AM Mackey Nature Cell Biology 18 (12), 1263-1265, 2016 | 12 | 2016 |
| Discovery of sterically-hindered phenol compounds with potent cytoprotective activities against ox-LDL–induced retinal pigment epithelial cell death as a potential pharmacotherapy G Gnanaguru, A Mackey, EY Choi, A Arta, FA Rossato, TW Gero, ... Free Radical Biology and Medicine 178, 360-368, 2022 | 5 | 2022 |
| Imaging rhodopsin degeneration in vivo in a new model of ocular ischemia in living mice J Ren, YI Chen, AM Mackey, PK Liu The FASEB Journal 30 (2), 612, 2016 | 5 | 2016 |
| Investigation of VEGF165 induced retinal vascular inflammation in vitro A Mackey, YSE Ng Investigative Ophthalmology & Visual Science 57 (12), 3199-3199, 2016 | 1 | 2016 |
| Compounds and compositions for inhibiting retinal pigment epithelium degeneration and methods using the same YSE Ng, G Gnanaguru, A Mackey, PA D'amore, D Scott US Patent 11,260,048, 2022 | | 2022 |
| Therapeutic effects of recombinant heparin-binding domain protein in a mouse model of diabetic retinopathy Z Ji, Y Su, A Mackey, YSE Ng Investigative Ophthalmology & Visual Science 62 (8), 1082-1082, 2021 | | 2021 |
| Peroxisome proliferator-activated receptor gamma selective agonists for inhibition of retinal pigment epithelium degeneration or geographic atrophy YSE Ng, G Gnanaguru, A Mackey, PA D'amore US Patent App. 17/171,528, 2021 | | 2021 |
| Therapeutic effects of recombinant heparin-binding domain (HBD) protein on VEGF-induced pathological leukostasis and angiogenesis in mouse models. Z Ji, Y Su, A Mackey, YSE Ng Investigative Ophthalmology & Visual Science 61 (7), 1170-1170, 2020 | | 2020 |
| Peroxisome proliferator-activated receptor gamma selective agonists for inhibition of retinal pigment epithelium degeneration or geographic atrophy YSE Ng, G Gnanaguru, A Mackey, PA D'amore US Patent App. 16/091,439, 2019 | | 2019 |
| Systematic treatment with trimethoprim/sulfamethoxazole (Ditrim) significantly inhibits spontaneous choroidal neovascularization (sCNV) in the JR5558 mouse model Y Su, F Rossato, A Mackey, YSE Ng Investigative Ophthalmology & Visual Science 59 (9), 70-70, 2018 | | 2018 |
| Targeting endothelial-to-mesenchymal transition (EndMT) driven fibrosis for choroidal neovascularization (CNV) in age-related macular degeneration (AMD) FA Rossato, Y Su, A Mackey, YSE Ng Investigative Ophthalmology & Visual Science 59 (9), 2629-2629, 2018 | | 2018 |