The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation G Leprivier, M Remke, B Rotblat, A Dubuc, ARF Mateo, M Kool, ... Cell 153 (5), 1064-1079, 2013 | 444 | 2013 |
The hitchhiker’s guide to the voltage-gated sodium channel galaxy CA Ahern, J Payandeh, F Bosmans, B Chanda Journal of General Physiology 147 (1), 1-24, 2016 | 353 | 2016 |
Structural basis of α-scorpion toxin action on Nav channels T Clairfeuille, A Cloake, DT Infield, JP Llongueras, CP Arthur, ZR Li, ... Science 363 (6433), eaav8573, 2019 | 170 | 2019 |
Focused electric field across the voltage sensor of potassium channels CA Ahern, R Horn Neuron 48 (1), 25-29, 2005 | 163 | 2005 |
Crystallographic basis for calcium regulation of sodium channels M Sarhan, F Van Petegem, CA Ahern Biophysical journal 102 (3), 325a, 2012 | 151 | 2012 |
Electrostatic contributions of aromatic residues in the local anesthetic receptor of voltage-gated sodium channels CA Ahern, AL Eastwood, DA Dougherty, R Horn Circulation research 102 (1), 86-94, 2008 | 144 | 2008 |
Stirring up controversy with a voltage sensor paddle CA Ahern, R Horn TRENDS in Neurosciences 27 (6), 303-307, 2004 | 124 | 2004 |
Modulation of the Cardiac Sodium Channel NaV1.5 by Fyn, a Src Family Tyrosine Kinase CA Ahern, JF Zhang, MJ Wookalis, R Horn Circulation research 96 (9), 991-998, 2005 | 123 | 2005 |
Engineered transfer RNAs for suppression of premature termination codons JD Lueck, JS Yoon, A Perales-Puchalt, AL Mackey, DT Infield, MA Behlke, ... Nature communications 10 (1), 822, 2019 | 115 | 2019 |
HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response B Rotblat, AL Southwell, DE Ehrnhoefer, NH Skotte, M Metzler, ... Proceedings of the National Academy of Sciences 111 (8), 3032-3037, 2014 | 108 | 2014 |
Contributions of counter-charge in a potassium channel voltage-sensor domain SA Pless, JD Galpin, AP Niciforovic, CA Ahern Nature chemical biology 7 (9), 617-623, 2011 | 102 | 2011 |
Molecular basis for class Ib anti-arrhythmic inhibition of cardiac sodium channels SA Pless, JD Galpin, A Frankel, CA Ahern Nature communications 2 (1), 351, 2011 | 101 | 2011 |
A cation-π interaction discriminates among sodium channels that are either sensitive or resistant to tetrodotoxin block VP Santarelli, AL Eastwood, DA Dougherty, R Horn, CA Ahern Journal of Biological Chemistry 282 (11), 8044-8051, 2007 | 99 | 2007 |
Investigating the Putative Glycine Hinge in Shaker Potassium Channel S Ding, L Ingleby, CA Ahern, R Horn The Journal of general physiology 126 (3), 213-226, 2005 | 97 | 2005 |
Cation-π interactions and their functional roles in membrane proteins DT Infield, A Rasouli, GD Galles, C Chipot, E Tajkhorshid, CA Ahern Journal of molecular biology 433 (17), 167035, 2021 | 90 | 2021 |
Specificity of charge-carrying residues in the voltage sensor of potassium channels CA Ahern, R Horn The Journal of general physiology 123 (3), 205-216, 2004 | 90 | 2004 |
Atomic basis for therapeutic activation of neuronal potassium channels RY Kim, MC Yau, JD Galpin, G Seebohm, CA Ahern, SA Pless, HT Kurata Nature communications 6 (1), 8116, 2015 | 88 | 2015 |
Unnatural amino acids as probes of ligand-receptor interactions and their conformational consequences SA Pless, CA Ahern Annual review of pharmacology and toxicology 53 (1), 211-229, 2013 | 83 | 2013 |
γ1 subunit interactions within the skeletal muscle L-type voltage-gated calcium channels J Arikkath, CC Chen, C Ahern, V Allamand, JD Flanagan, R Coronado, ... Journal of Biological Chemistry 278 (2), 1212-1219, 2003 | 73 | 2003 |
A cation–π interaction between extracellular TEA and an aromatic residue in potassium channels CA Ahern, AL Eastwood, HA Lester, DA Dougherty, R Horn The Journal of general physiology 128 (6), 649-657, 2006 | 72 | 2006 |