Articles with public access mandates - Jon M SteichenLearn more
Not available anywhere: 1
mRNA-LNP HIV-1 trimer boosters elicit precursors to broad neutralizing antibodies
Z Xie, YC Lin, JM Steichen, G Ozorowski, S Kratochvil, R Ray, JL Torres, ...
Science 384 (6697), eadk0582, 2024
Mandates: Bill & Melinda Gates Foundation
Available somewhere: 19
HIV vaccine design to target germline precursors of glycan-dependent broadly neutralizing antibodies
JM Steichen, DW Kulp, T Tokatlian, A Escolano, P Dosenovic, ...
Immunity 45 (3), 483-496, 2016
Mandates: US Department of Energy, Bill & Melinda Gates Foundation, US National …
Sequential immunization elicits broadly neutralizing anti-HIV-1 antibodies in Ig knockin mice
A Escolano, JM Steichen, P Dosenovic, DW Kulp, J Golijanin, D Sok, ...
Cell 166 (6), 1445-1458. e12, 2016
Mandates: US National Institutes of Health, Howard Hughes Medical Institute, Swedish …
PKA: lessons learned after twenty years
SS Taylor, P Zhang, JM Steichen, MM Keshwani, AP Kornev
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (7), 1271-1278, 2013
Mandates: US National Institutes of Health, Howard Hughes Medical Institute
Elicitation of robust tier 2 neutralizing antibody responses in nonhuman primates by HIV envelope trimer immunization using optimized approaches
M Pauthner, C Havenar-Daughton, D Sok, JP Nkolola, R Bastidas, ...
Immunity 46 (6), 1073-1088. e6, 2017
Mandates: Bill & Melinda Gates Foundation, US National Institutes of Health, Howard …
Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers
T Tokatlian, BJ Read, CA Jones, DW Kulp, S Menis, JYH Chang, ...
Science 363 (6427), 649-654, 2019
Mandates: Bill & Melinda Gates Foundation, US National Institutes of Health, US Agency …
Evolution of the eukaryotic protein kinases as dynamic molecular switches
SS Taylor, MM Keshwani, JM Steichen, AP Kornev
Philosophical Transactions of the Royal Society B: Biological Sciences 367 …, 2012
Mandates: US National Institutes of Health
A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses
JM Steichen, YC Lin, C Havenar-Daughton, S Pecetta, G Ozorowski, ...
Science 366 (6470), eaax4380, 2019
Mandates: Bill & Melinda Gates Foundation, US National Institutes of Health
Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding
DW Kulp, JM Steichen, M Pauthner, X Hu, T Schiffner, A Liguori, ...
Nature communications 8 (1), 1655, 2017
Mandates: Bill & Melinda Gates Foundation, US National Institutes of Health
Structural basis for the regulation of protein kinase A by activation loop phosphorylation
JM Steichen, M Kuchinskas, MM Keshwani, J Yang, JA Adams, SS Taylor
Journal of Biological Chemistry 287 (18), 14672-14680, 2012
Mandates: US National Institutes of Health, Howard Hughes Medical Institute
Global Consequences of Activation Loop Phosphorylation on Protein Kinase A 2
JM Steichen, GH Iyer, S Li, SA Saldanha, MS Deal, VL Woods, SS Taylor
Journal of Biological Chemistry 285 (6), 3825-3832, 2010
Mandates: US National Institutes of Health
Phosphoryl transfer by protein kinase A is captured in a crystal lattice
AC Bastidas, MS Deal, JM Steichen, Y Guo, J Wu, SS Taylor
Journal of the American Chemical Society 135 (12), 4788-4798, 2013
Mandates: US National Institutes of Health, Howard Hughes Medical Institute
Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses
JMJ Tas, JH Koo, YC Lin, Z Xie, JM Steichen, AM Jackson, BM Hauser, ...
Immunity 55 (10), 1856-1871. e6, 2022
Mandates: Bill & Melinda Gates Foundation, US National Institutes of Health
Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase
AC Bastidas, MS Deal, JM Steichen, MM Keshwani, Y Guo, SS Taylor
Journal of molecular biology 422 (2), 215-229, 2012
Mandates: US National Institutes of Health, Howard Hughes Medical Institute
A conserved Glu–Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold
J Yang, J Wu, JM Steichen, AP Kornev, MS Deal, S Li, B Sankaran, ...
Journal of molecular biology 415 (4), 666-679, 2012
Mandates: US National Institutes of Health
One‐step CRISPR/Cas9 method for the rapid generation of human antibody heavy chain knock‐in mice
YC Lin, S Pecetta, JM Steichen, S Kratochvil, E Melzi, J Arnold, ...
The EMBO journal 37 (18), e99243, 2018
Mandates: US National Institutes of Health
Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors
JR Willis, ZT Berndsen, KM Ma, JM Steichen, T Schiffner, E Landais, ...
Immunity 55 (11), 2149-2167. e9, 2022
Mandates: Bill & Melinda Gates Foundation, US National Institutes of Health
Membrane-bound mRNA immunogens lower the threshold to activate HIV Env V2 apex-directed broadly neutralizing B cell precursors in humanized mice
E Melzi, JR Willis, KM Ma, YC Lin, S Kratochvil, ZT Berndsen, EA Landais, ...
Immunity 55 (11), 2168-2186. e6, 2022
Mandates: Bill & Melinda Gates Foundation, US National Institutes of Health
Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates
JM Steichen, I Phung, E Salcedo, G Ozorowski, JR Willis, S Baboo, ...
Science 384 (6697), eadj8321, 2024
Mandates: Bill & Melinda Gates Foundation
Optimization of an alum-anchored clinical HIV vaccine candidate
KA Rodrigues, CA Cottrell, JM Steichen, B Groschel, W Abraham, H Suh, ...
npj Vaccines 8 (1), 117, 2023
Mandates: US Department of Defense, US National Institutes of Health, Howard Hughes …
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