Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2. 0 J Schellenberger, R Que, RMT Fleming, I Thiele, JD Orth, AM Feist, ... Nature protocols 6 (9), 1290-1307, 2011 | 1630 | 2011 |
COBRApy: constraints-based reconstruction and analysis for python A Ebrahim, JA Lerman, BO Palsson, DR Hyduke BMC systems biology 7, 1-6, 2013 | 1220 | 2013 |
Genome‐scale models of metabolism and gene expression extend and refine growth phenotype prediction EJ O'brien, JA Lerman, RL Chang, DR Hyduke, BØ Palsson Molecular systems biology 9 (1), 693, 2013 | 532 | 2013 |
In silico method for modelling metabolism and gene product expression at genome scale JA Lerman, DR Hyduke, H Latif, VA Portnoy, NE Lewis, JD Orth, ... Nature communications 3 (1), 929, 2012 | 353 | 2012 |
Nitric oxide is consumed, rather than conserved, by reaction with oxyhemoglobin under physiological conditions MS Joshi, TB Ferguson Jr, TH Han, DR Hyduke, JC Liao, T Rassaf, ... Proceedings of the National Academy of Sciences 99 (16), 10341-10346, 2002 | 268 | 2002 |
Modulation of nitric oxide bioavailability by erythrocytes KT Huang, TH Han, DR Hyduke, MW Vaughn, H Van Herle, TW Hein, ... Proceedings of the National Academy of Sciences 98 (20), 11771-11776, 2001 | 235 | 2001 |
SBML Level 3: an extensible format for the exchange and reuse of biological models SM Keating, D Waltemath, M König, F Zhang, A Dräger, C Chaouiya, ... Molecular systems biology 16 (8), e9110, 2020 | 225 | 2020 |
Analysis of omics data with genome-scale models of metabolism DR Hyduke, NE Lewis, BØ Palsson Molecular BioSystems 9 (2), 167-174, 2013 | 223 | 2013 |
AMP-activated protein kinase promotes human prostate cancer cell growth and survival HU Park, S Suy, M Danner, V Dailey, Y Zhang, H Li, DR Hyduke, ... Molecular cancer therapeutics 8 (4), 733-741, 2009 | 209 | 2009 |
Model‐driven multi‐omic data analysis elucidates metabolic immunomodulators of macrophage activation A Bordbar, ML Mo, ES Nakayasu, AC Schrimpe‐Rutledge, YM Kim, ... Molecular systems biology 8 (1), 558, 2012 | 182 | 2012 |
Integrated network analysis identifies nitric oxide response networks and dihydroxyacid dehydratase as a crucial target in Escherichia coli DR Hyduke, LR Jarboe, LM Tran, KJY Chou, JC Liao Proceedings of the National Academy of Sciences 104 (20), 8484-8489, 2007 | 180 | 2007 |
A community effort towards a knowledge-base and mathematical model of the human pathogen Salmonella Typhimurium LT2 I Thiele, DR Hyduke, B Steeb, G Fankam, DK Allen, S Bazzani, ... BMC systems biology 5, 1-9, 2011 | 171 | 2011 |
GIM3E: condition-specific models of cellular metabolism developed from metabolomics and expression data BJ Schmidt, A Ebrahim, TO Metz, JN Adkins, BØ Palsson, DR Hyduke Bioinformatics 29 (22), 2900-2908, 2013 | 165 | 2013 |
Towards genome-scale signalling-network reconstructions DR Hyduke, BØ Palsson Nature Reviews Genetics 11 (4), 297-307, 2010 | 163 | 2010 |
Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in … I Moffat, NL Chepelev, S Labib, J Bourdon-Lacombe, B Kuo, JK Buick, ... Critical reviews in toxicology 45 (1), 1-43, 2015 | 157 | 2015 |
Pore size analysis of activated carbons from argon and nitrogen porosimetry using density functional theory RJ Dombrowski, DR Hyduke, CM Lastoskie Langmuir 16 (11), 5041-5050, 2000 | 152 | 2000 |
Nitric oxide reaction with red blood cells and hemoglobin under heterogeneous conditions TH Han, DR Hyduke, MW Vaughn, JM Fukuto, JC Liao Proceedings of the National Academy of Sciences 99 (11), 7763-7768, 2002 | 138 | 2002 |
Development of a toxicogenomics signature for genotoxicity using a dose‐optimization and informatics strategy in human cells HH Li, DR Hyduke, R Chen, P Heard, CL Yauk, J Aubrecht, AJ Fornace Jr Environmental and molecular mutagenesis 56 (6), 505-519, 2015 | 98 | 2015 |
Regulation of nitric oxide consumption by hypoxic red blood cells TH Han, E Qamirani, AG Nelson, DR Hyduke, G Chaudhuri, L Kuo, ... Proceedings of the National Academy of Sciences 100 (21), 12504-12509, 2003 | 83 | 2003 |
The Horvath–Kawazoe method revisited RJ Dombrowski, CM Lastoskie, DR Hyduke Colloids and Surfaces A: Physicochemical and Engineering Aspects 187, 23-39, 2001 | 82 | 2001 |