Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization F Zindy, CM Eischen, DH Randle, T Kamijo, JL Cleveland, CJ Sherr, ... Genes & development 12 (15), 2424-2433, 1998 | 1629 | 1998 |
Disruption of the ARF–Mdm2–p53 tumor suppressor pathway in Myc-induced lymphomagenesis CM Eischen, JD Weber, MF Roussel, CJ Sherr, JL Cleveland Genes & development 13 (20), 2658-2669, 1999 | 1029 | 1999 |
Comparison of apoptosis in wild-type and Fas-resistant cells: chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions CM Eischen, TJ Kottke, LM Martins, GS Basi, JS Tung, WC Earnshaw, ... Blood 90 (3), 935-943, 1997 | 325 | 1997 |
Interaction with WDR5 Promotes Target Gene Recognition and Tumorigenesis by MYC LR Thomas, Q Wang, BC Grieb, J Phan, AM Foshage, Q Sun, ... Molecular cell, 2015 | 295 | 2015 |
Apoptosis triggered by Myc-induced suppression of Bcl-XL or Bcl-2 is bypassed during lymphomagenesis CM Eischen, D Woo, MF Roussel, JL Cleveland Molecular and cellular biology 21 (15), 5063-5070, 2001 | 275 | 2001 |
Tyrosine kinase activation provides an early and requisite signal for Fas-induced apoptosis. CM Eischen, CJ Dick, PJ Leibson The Journal of immunology 153 (5), 1947-1954, 1994 | 247 | 1994 |
Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis CM Eischen, MF Roussel, SJ Korsmeyer, JL Cleveland Molecular and cellular biology 21 (22), 7653-7662, 2001 | 238 | 2001 |
Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells R Mudhasani, Z Zhu, G Hutvagner, CM Eischen, S Lyle, LL Hall, ... The Journal of cell biology 181 (7), 1055-1063, 2008 | 224 | 2008 |
Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1. CM Eischen, G Packham, J Nip, BE Fee, SW Hiebert, GP Zambetti, ... Oncogene 20 (48), 6983-6993, 2001 | 212 | 2001 |
Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus JS Braun, R Novak, PJ Murray, CM Eischen, SA Susin, G Kroemer, ... Journal of Infectious Diseases 184 (10), 1300-1309, 2001 | 182 | 2001 |
Fc receptor-induced expression of Fas ligand on activated NK cells facilitates cell-mediated cytotoxicity and subsequent autocrine NK cell apoptosis. CM Eischen, JD Schilling, DH Lynch, PH Krammer, PJ Leibson The Journal of Immunology 156 (8), 2693-2699, 1996 | 168 | 1996 |
Mdm2 haplo‐insufficiency profoundly inhibits Myc‐induced lymphomagenesis JR Alt, TC Greiner, JL Cleveland, CM Eischen The EMBO journal 22 (6), 1442-1450, 2003 | 160 | 2003 |
Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair JR Alt, A Bouska, MR Fernandez, RL Cerny, H Xiao, CM Eischen Journal of Biological Chemistry 280 (19), 18771-18781, 2005 | 135 | 2005 |
Selective regulation of Bcl-XL by a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies G Packham, EL White, CM Eischen, H Yang, E Parganas, JN Ihle, ... Genes & development 12 (16), 2475-2487, 1998 | 132 | 1998 |
Glycolytic rate and lymphomagenesis depend on PARP14, an ADP ribosyltransferase of the B aggressive lymphoma (BAL) family SH Cho, AK Ahn, P Bhargava, CH Lee, CM Eischen, O McGuinness, ... Proceedings of the National Academy of Sciences 108 (38), 15972-15977, 2011 | 124 | 2011 |
Mdm2 promotes genetic instability and transformation independent of p53 A Bouska, T Lushnikova, S Plaza, CM Eischen Molecular and cellular biology 28 (15), 4862-4874, 2008 | 119 | 2008 |
PARP-14, a member of the B aggressive lymphoma family, transduces survival signals in primary B cells SH Cho, S Goenka, T Henttinen, P Gudapati, A Reinikainen, CM Eischen, ... Blood 113 (11), 2416-2425, 2009 | 115 | 2009 |
The RING domain of Mdm2 can inhibit cell proliferation J Dang, ML Kuo, CM Eischen, L Stepanova, CJ Sherr, MF Roussel Cancer research 62 (4), 1222-1230, 2002 | 112 | 2002 |
Inhibition of histone deacetylase 3 causes replication stress in cutaneous T cell lymphoma CE Wells, S Bhaskara, KR Stengel, Y Zhao, B Sirbu, B Chagot, D Cortez, ... PloS one 8 (7), e68915, 2013 | 111 | 2013 |
miR-223 Regulates cell growth and targets proto-oncogenes in mycosis fungoides/cutaneous T-cell lymphoma LY McGirt, CM Adams, DA Baerenwald, JP Zwerner, JA Zic, CM Eischen Journal of Investigative Dermatology 134 (4), 1101-1107, 2014 | 91 | 2014 |