MuSyC is a consensus framework that unifies multi-drug synergy metrics for combinatorial drug discovery DJ Wooten, CT Meyer, ALR Lubbock, V Quaranta, CF Lopez Nature communications 12 (1), 4607, 2021 | 55 | 2021 |
Carbonic anhydrase 9 expression increases with vascular endothelial growth factor–targeted therapy and is predictive of outcome in metastatic clear cell renal cancer GD Stewart, FC O’Mahony, A Laird, S Rashid, SA Martin, L Eory, ... European urology 66 (5), 956-963, 2014 | 51 | 2014 |
Integrated, high-throughput, multiomics platform enables data-driven construction of cellular responses and reveals global drug mechanisms of action JL Norris, MA Farrow, DB Gutierrez, LD Palmer, N Muszynski, SD Sherrod, ... Journal of proteome research 16 (3), 1364-1375, 2017 | 45 | 2017 |
Sunitinib treatment exacerbates intratumoral heterogeneity in metastatic renal cancer GD Stewart, FC O'Mahony, A Laird, L Eory, ALR Lubbock, A Mackay, ... Clinical Cancer Research 21 (18), 4212-4223, 2015 | 34 | 2015 |
GPU-powered model analysis with PySB/cupSODA LA Harris, MS Nobile, JC Pino, ALR Lubbock, D Besozzi, G Mauri, ... Bioinformatics 33 (21), 3492-3494, 2017 | 22 | 2017 |
TMA Navigator: Network inference, patient stratification and survival analysis with tissue microarray data ALR Lubbock, E Katz, DJ Harrison, IM Overton Nucleic Acids Research 41 (W1), W562-W568, 2013 | 22 | 2013 |
ACDC: Automated cell detection and counting for time-lapse fluorescence microscopy L Rundo, A Tangherloni, DR Tyson, R Betta, C Militello, S Spolaor, ... Applied Sciences 10 (18), 6187, 2020 | 11 | 2020 |
Overcoming intratumoural heterogeneity for reproducible molecular risk stratification: a case study in advanced kidney cancer ALR Lubbock, GD Stewart, FC O’Mahony, A Laird, P Mullen, M O’Donnell, ... BMC medicine 15, 1-12, 2017 | 11 | 2017 |
Thunor: visualization and analysis of high-throughput dose–response datasets ALR Lubbock, LA Harris, V Quaranta, DR Tyson, CF Lopez Nucleic Acids Research 49 (W1), W633-W640, 2021 | 10 | 2021 |
SynLeGG: analysis and visualization of multiomics data for discovery of cancer ‘Achilles heels’ and gene function relationships M Wappett, A Harris, ALR Lubbock, I Lobb, S McDade, IM Overton Nucleic Acids Research 49 (W1), W613-W618, 2021 | 9 | 2021 |
Functional transcription factor target networks illuminate control of epithelial remodelling IM Overton, AH Sims, JA Owen, BSE Heale, MJ Ford, ALR Lubbock, ... Cancers 12 (10), 2823, 2020 | 9 | 2020 |
Processes in DNA damage response from a whole-cell multi-omics perspective JC Pino, ALR Lubbock, LA Harris, DB Gutierrez, MA Farrow, N Muszynski, ... Iscience 25 (11), 2022 | 5 | 2022 |
Programmatic modeling for biological systems ALR Lubbock, CF Lopez Current opinion in systems biology 27, 100343, 2021 | 5 | 2021 |
Selective inhibition of JAK1 primes STAT5-driven human leukemia cells for ATRA-induced differentiation HE Ramsey, K Stengel, JC Pino, G Johnston, M Childress, AE Gorska, ... Targeted oncology 16, 663-674, 2021 | 2 | 2021 |
Visualization and analysis of high-throughput in vitro dose–response datasets with Thunor ALR Lubbock, LA Harris, V Quaranta, DR Tyson, CF Lopez bioRxiv, 530329, 2019 | 2 | 2019 |
The effect of sunitinib on biomarkers and tumor heterogeneity in metastatic clear cell renal cancer. G Stewart, A Laird, F O'Mahony, L Eory, A Lubbock, J Nanda, M O'Donnell, ... Journal of Clinical Oncology 32 (4_suppl), 408-408, 2014 | 2 | 2014 |
Microbench: automated metadata management for systems biology benchmarking and reproducibility in Python ALR Lubbock, CF Lopez Bioinformatics 38 (20), 4823-4825, 2022 | 1 | 2022 |
A computational framework to explore cellular response mechanisms from multi-omics datasets JC Pino, ALR Lubbock, LA Harris, DB Gutierrez, MA Farrow, N Muszynski, ... bioRxiv, 2020.03. 02.974121, 2020 | 1 | 2020 |
Accelerated simulations of chemical reaction systems using the stochastic simulation algorithm on GPUs JC Pino, M Prugger, ALR Lubbock, LA Harris, CF Lopez bioRxiv, 2020.02. 14.948612, 2020 | 1 | 2020 |
Ursprung: Provenance for Large-Scale Analytics Environments L Rupprecht, JC Davis, C Arnold, A Lubbock, D Tyson, D Bhagwat Proceedings of the 2019 International Conference on Management of Data, 1989 …, 2019 | | 2019 |