Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma Y Yang, AL Shaffer, NCT Emre, M Ceribelli, M Zhang, G Wright, W Xiao, ... Cancer cell 21 (6), 723-737, 2012 | 605 | 2012 |
Phase I trial of the novel mammalian target of rapamycin inhibitor deforolimus (AP23573; MK-8669) administered intravenously daily for 5 days every 2 weeks to patients with … MM Mita, AC Mita, QS Chu, EK Rowinsky, GJ Fetterly, M Goldston, ... Journal of Clinical Oncology 26 (3), 361-367, 2008 | 316 | 2008 |
The cancer stem cell niche—there goes the neighborhood? SM Cabarcas, LA Mathews, WL Farrar International journal of cancer 129 (10), 2315-2327, 2011 | 310 | 2011 |
Invasive prostate cancer cells are tumor initiating cells that have a stem cell-like genomic signature GJ Klarmann, EM Hurt, LA Mathews, X Zhang, MA Duhagon, T Mistree, ... Clinical & experimental metastasis 26, 433-446, 2009 | 267 | 2009 |
Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome GW Rhyasen, L Bolanos, J Fang, A Jerez, M Wunderlich, C Rigolino, ... Cancer cell 24 (1), 90-104, 2013 | 213 | 2013 |
Pharmacologic disruption of Polycomb Repressive Complex 2 inhibits tumorigenicity and tumor progression in prostate cancer F Crea, EM Hurt, LA Mathews, SM Cabarcas, L Sun, VE Marquez, ... Molecular cancer 10, 1-10, 2011 | 204 | 2011 |
Epigenetic regulation of SOX9 by the NF-κB signaling pathway in pancreatic cancer stem cells L Sun, LA Mathews, SM Cabarcas, X Zhang, A Yang, Y Zhang, MR Young, ... Stem cells 31 (8), 1454-1466, 2013 | 145 | 2013 |
Increased expression of DNA repair genes in invasive human pancreatic cancer cells LA Mathews, SM Cabarcas, EM Hurt, X Zhang, EM Jaffee, WL Farrar Pancreas 40 (5), 730-739, 2011 | 94 | 2011 |
Epigenetic gene regulation in stem cells and correlation to cancer LA Mathews, F Crea, WL Farrar Differentiation 78 (1), 1-17, 2009 | 93 | 2009 |
Estrogen and progesterone regulate radiation-induced p53 activity in mammary epithelium through TGF-β-dependent pathways KA Becker, S Lu, ES Dickinson, KA Dunphy, L Mathews, SS Schneider, ... Oncogene 24 (42), 6345-6353, 2005 | 51 | 2005 |
Inhibition of ceramide metabolism sensitizes human leukemia cells to inhibition of BCL2-like proteins L Casson, L Howell, LA Mathews, M Ferrer, N Southall, R Guha, JM Keller, ... PloS one 8 (1), e54525, 2013 | 49 | 2013 |
DNA repair: the culprit for tumor-initiating cell survival? LA Mathews, SM Cabarcas, WL Farrar Cancer and metastasis reviews 30, 185-197, 2011 | 49 | 2011 |
Epigenetic regulation of CpG promoter methylation in invasive prostate cancer cells LA Mathews, EM Hurt, X Zhang, WL Farrar Molecular cancer 9, 1-17, 2010 | 42 | 2010 |
A 1536-well quantitative high-throughput screen to identify compounds targeting cancer stem cells LA Mathews, JM Keller, BL Goodwin, R Guha, P Shinn, R Mull, ... Journal of biomolecular screening 17 (9), 1231-1242, 2012 | 41 | 2012 |
Transcriptional responses to estrogen and progesterone in mammary gland identify networks regulating p53 activity S Lu, KA Becker, MJ Hagen, H Yan, AL Roberts, LA Mathews, ... Endocrinology 149 (10), 4809-4820, 2008 | 41 | 2008 |
Targeting prostate cancer stem cells F Crea, LA Mathews, WL Farrar, EM Hurt Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2009 | 35 | 2009 |
DNA repair of cancer stem cells LA Mathews, SM Cabarcas, EM Hurt Springer, 2013 | 30 | 2013 |
Cryptotanshinone targets tumor-initiating cells through down-regulation of stemness genes expression Y Zhang, SM Cabarcas, JI Zheng, L Sun, LA Mathews, X Zhang, H Lin, ... Oncology Letters 11 (6), 3803-3812, 2016 | 19 | 2016 |
The differentiation of pancreatic tumor-initiating cells by vitronectin can be blocked by cilengitide SM Cabarcas, L Sun, L Mathews, S Thomas, X Zhang, WL Farrar Pancreas 42 (5), 861-870, 2013 | 9 | 2013 |
Multiplexing High‐Content Flow (HCF) and Quantitative High‐Throughput Screening (qHTS) to Identify Compounds Capable of Decreasing Cell Viability, Activating Caspase 3/7 … LA Mathews, JM Keller, C McKnight, S Michael, P Shinn, D Liu, LM Staudt, ... Current Protocols in Chemical Biology 5 (3), 195-212, 2013 | 7 | 2013 |