Articles with public access mandates - Antonio LavecchiaLearn more
Not available anywhere: 17
In silico methods to address polypharmacology: current status, applications and future perspectives
A Lavecchia, C Cerchia
Drug Discovery Today 21 (2), 288-298, 2016
Mandates: Government of Italy
Novel non-peptide small molecules preventing IKKβ/NEMO association inhibit NF-κB activation in LPS-stimulated J774 macrophages
F De Falco, C Di Giovanni, C Cerchia, D De Stefano, A Capuozzo, C Irace, ...
Biochemical pharmacology 104, 83-94, 2016
Mandates: US National Institutes of Health, Government of Italy
Pharmacophore hybridization approach to discover novel pyrazoline-based hydantoin analogs with anti-tumor efficacy
N Upadhyay, K Tilekar, F Loiodice, NY Anisimova, TS Spirina, ...
Bioorganic Chemistry 107, 104527, 2021
Mandates: Department of Science & Technology, India
Design, synthesis and biological evaluation of a class of bioisosteric oximes of the novel dual peroxisome proliferator-activated receptor α/γ ligand LT175
L Piemontese, G Fracchiolla, A Carrieri, M Parente, A Laghezza, ...
European journal of medicinal chemistry 90, 583-594, 2015
Mandates: Fondazione Cariplo, Government of Italy
Identification of noncovalent proteasome inhibitors with high selectivity for chymotrypsin-like activity by a multistep structure-based virtual screening
C Di Giovanni, R Ettari, S Sarno, A Rotondo, A Bitto, F Squadrito, ...
European journal of medicinal chemistry 121, 578-591, 2016
Mandates: Government of Italy
Novel inhibitors of signal transducer and activator of transcription 3 signaling pathway: an update on the recent patent literature
A Lavecchia, C Di Giovanni, C Cerchia
Expert opinion on therapeutic patents 24 (4), 383-400, 2014
Mandates: Government of Italy
Current status and future prospects of molecular hybrids with thiazolidinedione (TZD) scaffold in anticancer drug discovery
K Tilekar, O Shelke, N Upadhyay, A Lavecchia, CS Ramaa
Journal of Molecular Structure 1250, 131767, 2022
Mandates: Department of Science & Technology, India
Synthesis and biological evaluation of pyrazoline and pyrrolidine‐2, 5‐dione hybrids as potential antitumor agents
K Tilekar, N Upadhyay, FJ Meyer‐Almes, F Loiodice, NY Anisimova, ...
ChemMedChem 15 (19), 1813-1825, 2020
Mandates: Department of Science & Technology, India
Recent advances in developing PCSK9 inhibitors for lipid-lowering therapy
A Lavecchia, C Cerchia
Future medicinal chemistry 11 (5), 423-441, 2019
Mandates: Government of Italy
Discovery of novel naphthylphenylketone and naphthylphenylamine derivatives as cell division cycle 25B (CDC25B) phosphatase inhibitors: design, synthesis, inhibition mechanism …
C Cerchia, R Nasso, M Mori, S Villa, A Gelain, A Capasso, F Aliotta, ...
Journal of Medicinal Chemistry 62 (15), 7089-7110, 2019
Mandates: Government of Italy
Synthesis of Polysubstituted 3-Chalcogenated Indoles through Copper (I) Iodide-Catalyzed Three-Component Domino Reactions
R Gou, Y Zhang, S Wu, F Liu
Synlett 30 (02), 207-212, 2019
Mandates: National Natural Science Foundation of China
Synthesis of 3-Sulfenylindoles from Indoles and Various Sulfenylation Agents through Aerobic Oxidative C–S Bond Coupling
C Xu, S Yi, M Li, X Hu, N Sun, L Jin, B Hu, Z Shen
Synlett 29 (14), 1914-1920, 2018
Mandates: National Natural Science Foundation of China
New Efficient Synthesis of 1, 2, 4-Trisubstituted Furans by a Sequential Passerini/Wittig/Isomerization Reaction Starting from Baylis–Hillman β-Bromo Aldehydes
ZL Ren, M Sun, ZR Guan, MW Ding
Synlett 29 (01), 106-110, 2018
Mandates: National Natural Science Foundation of China
Structure-Based Design, Synthesis, and In Vivo Antinociceptive Effects of Selective A1 Adenosine Receptor Agonists
R Petrelli, M Scortichini, C Belardo, S Boccella, L Luongo, F Capone, ...
Journal of Medicinal Chemistry 61 (1), 305-318, 2018
Mandates: Government of Italy
Amorfrutins are efficient modulators of peroxisome proliferator-activated receptor gamma (PPARγ) with potent antidiabetic and anticancer properties: a patent evaluation of …
A Lavecchia, C Di Giovanni
Expert Opinion on Therapeutic Patents 25 (11), 1341-1347, 2015
Mandates: Government of Italy
Iodine-Promoted Synthesis of 4-Aryl-2-(arylsulfonyl) quinolones by Desulfurative C–S Cross-Coupling Reaction of Quinoline-2-thiones with Sodium Sulfinates
GC Yang, XC Wang, ZJ Quan
Synlett 31 (15), 1527-1531, 2020
Mandates: National Natural Science Foundation of China
A New Antidiabetic Agent Showing Short-and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier …
A Laghezza, C Cerchia, M Genovese, R Leuci, E Pranzini, A Santi, ...
Journal of Medicinal Chemistry 66 (5), 3566-3587, 2023
Mandates: Government of Italy
Available somewhere: 38
Machine-learning approaches in drug discovery: methods and applications
A Lavecchia
Drug discovery today 20 (3), 318-331, 2015
Mandates: Government of Italy
Virtual screening strategies in drug discovery: a critical review
A Lavecchia, C Di Giovanni
Current medicinal chemistry 20 (23), 2839-2860, 2013
Mandates: Fondazione Cariplo, Government of Italy
Design and Synthesis of 2-Heterocyclyl-3-arylthio-1H-indoles as Potent Tubulin Polymerization and Cell Growth Inhibitors with Improved Metabolic Stability
G La Regina, R Bai, W Rensen, A Coluccia, F Piscitelli, V Gatti, ...
Journal of medicinal chemistry 54 (24), 8394-8406, 2011
Mandates: US National Institutes of Health
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