Sodium butyrate abolishes lipopolysaccharide-induced depression-like behaviors and hippocampal microglial activation in mice Y Yamawaki, N Yoshioka, K Nozaki, H Ito, K Oda, K Harada, S Shirawachi, ... Brain research 1680, 13-38, 2018 | 172 | 2018 |
Mutant huntingtin impairs Ku70-mediated DNA repair Y Enokido, T Tamura, H Ito, A Arumughan, A Komuro, H Shiwaku, M Sone, ... Journal of Cell Biology 189 (3), 425-443, 2010 | 153 | 2010 |
A mouse model of X-linked intellectual disability associated with impaired removal of histone methylation S Iwase, E Brookes, S Agarwal, AI Badeaux, H Ito, CN Vallianatos, ... Cell reports 14 (5), 1000-1009, 2016 | 127 | 2016 |
Age-dependent change of HMGB1 and DNA double-strand break accumulation in mouse brain Y Enokido, A Yoshitake, H Ito, H Okazawa Biochemical and biophysical research communications 376 (1), 128-133, 2008 | 103 | 2008 |
HMGB 1 facilitates repair of mitochondrial DNA damage and extends the lifespan of mutant ataxin‐1 knock‐in mice H Ito, K Fujita, K Tagawa, X Chen, H Homma, T Sasabe, J Shimizu, ... EMBO molecular medicine 7 (1), 78-101, 2015 | 87 | 2015 |
A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseases K Fujita, Y Nakamura, T Oka, H Ito, T Tamura, K Tagawa, T Sasabe, ... Nature communications 4 (1), 1816, 2013 | 87 | 2013 |
Comprehensive phosphoproteome analysis unravels the core signaling network that initiates the earliest synapse pathology in preclinical Alzheimer's disease brain K Tagawa, H Homma, A Saito, K Fujita, X Chen, S Imoto, T Oka, H Ito, ... Human molecular genetics 24 (2), 540-558, 2015 | 85 | 2015 |
Ataxin-7 associates with microtubules and stabilizes the cytoskeletal network Y Nakamura, K Tagawa, T Oka, T Sasabe, H Ito, H Shiwaku, AR La Spada, ... Human molecular genetics 21 (5), 1099-1110, 2012 | 61 | 2012 |
In utero gene therapy rescues microcephaly caused by Pqbp1-hypofunction in neural stem progenitor cells H Ito, H Shiwaku, C Yoshida, H Homma, H Luo, X Chen, K Fujita, ... Molecular psychiatry 20 (4), 459-471, 2015 | 45 | 2015 |
Dynamic changes of the phosphoproteome in postmortem mouse brains T Oka, K Tagawa, H Ito, H Okazawa PloS one 6 (6), e21405, 2011 | 41 | 2011 |
Omi/HtrA2 is relevant to the selective vulnerability of striatal neurons in Huntington’s disease R Inagaki, K Tagawa, ML Qi, Y Enokido, H Ito, T Tamura, S Shimizu, ... European Journal of Neuroscience 28 (1), 30-40, 2008 | 38 | 2008 |
Dopaminergic signaling in the nucleus accumbens modulates stress-coping strategies during inescapable stress W Cui, T Aida, H Ito, K Kobayashi, Y Wada, S Kato, T Nakano, M Zhu, ... Journal of Neuroscience 40 (38), 7241-7254, 2020 | 36 | 2020 |
Antidepressant effect of the translocator protein antagonist ONO-2952 on mouse behaviors under chronic social defeat stress K Nozaki, H Ito, M Ohgidani, Y Yamawaki, EH Sahin, T Kitajima, ... Neuropharmacology 162, 107835, 2020 | 34 | 2020 |
Knock-down of PQBP1 impairs anxiety-related cognition in mouse H Ito, N Yoshimura, M Kurosawa, S Ishii, N Nukina, H Okazawa Human molecular genetics 18 (22), 4239-4254, 2009 | 32 | 2009 |
Systems biology analysis of Drosophila in vivo screen data elucidates core networks for DNA damage repair in SCA1 SS Barclay, T Tamura, H Ito, K Fujita, K Tagawa, T Shimamura, A Katsuta, ... Human molecular genetics 23 (5), 1345-1364, 2014 | 27 | 2014 |
Sox2 transcriptionally regulates PQBP1, an intellectual disability-microcephaly causative gene, in neural stem progenitor cells C Li, H Ito, K Fujita, H Shiwaku, Y Qi, K Tagawa, T Tamura, H Okazawa PLoS One 8 (7), e68627, 2013 | 21 | 2013 |
Mycotic aneurysm in the aortic arch of a horse associated with invasive aspergillosis M Okamoto, M Kamitani, N Tunoda, M Tagami, N Nagamine, K Kawata, ... The Veterinary Record 160 (8), 268, 2007 | 18 | 2007 |
Developmental YAPdeltaC determines adult pathology in a model of spinocerebellar ataxia type 1 K Fujita, Y Mao, S Uchida, X Chen, H Shiwaku, T Tamura, H Ito, K Watase, ... Nature Communications 8 (1), 1864, 2017 | 16 | 2017 |
Intussusception of the spiral colon associated with fibroserous granulation in a heifer M Okamoto, H Itoh, M Koiwa, M Inagaki, T Nadao, T Kurosawa, ... The Veterinary Record 160 (11), 376, 2007 | 15 | 2007 |
Activation of proprotein convertase in the mouse habenula causes depressive-like behaviors through remodeling of extracellular matrix H Ito, K Nozaki, K Sakimura, M Abe, S Yamawaki, H Aizawa Neuropsychopharmacology 46 (2), 442-454, 2021 | 11 | 2021 |