Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation P Xu, DM Duong, NT Seyfried, D Cheng, Y Xie, J Robert, J Rush, ... Cell 137 (1), 133-145, 2009 | 1416 | 2009 |
Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation ECB Johnson, EB Dammer, DM Duong, L Ping, M Zhou, L Yin, ... Nature medicine 26 (5), 769-780, 2020 | 707 | 2020 |
TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD CC Chou, YI Zhang, ME Umoh, SW Vaughan, I Lorenzini, F Liu, ... Nature neuroscience 21 (2), 228-239, 2018 | 530 | 2018 |
Continuous release of endostatin from microencapsulated engineered cells for tumor therapy T Joki, M Machluf, A Atala, J Zhu, NT Seyfried, IF Dunn, T Abe, RS Carroll, ... Nature biotechnology 19 (1), 35-39, 2001 | 484 | 2001 |
Evidence for brain glucose dysregulation in Alzheimer's disease Y An, VR Varma, S Varma, R Casanova, E Dammer, O Pletnikova, ... Alzheimer's & dementia 14 (3), 318-329, 2018 | 436 | 2018 |
Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease Z Zhang, M Song, X Liu, SS Kang, IS Kwon, DM Duong, NT Seyfried, ... Nature medicine 20 (11), 1254-1262, 2014 | 425 | 2014 |
A multi-network approach identifies protein-specific co-expression in asymptomatic and symptomatic Alzheimer’s disease NT Seyfried, EB Dammer, V Swarup, D Nandakumar, DM Duong, L Yin, ... Cell systems 4 (1), 60-72. e4, 2017 | 414 | 2017 |
Expression of cyclooxygenase 2 (COX-2) in human glioma and in vitro inhibition by a specific COX-2 inhibitor, NS-398 T Joki, O Heese, DC Nikas, L Bello, J Zhang, SK Kraeft, NT Seyfried, ... Cancer research 60 (17), 4926-4931, 2000 | 379 | 2000 |
Posttranslational modifications mediate the structural diversity of tauopathy strains T Arakhamia, CE Lee, Y Carlomagno, M Kumar, DM Duong, H Wesseling, ... Cell 180 (4), 633-644. e12, 2020 | 351 | 2020 |
The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease M Wang, ND Beckmann, P Roussos, E Wang, X Zhou, Q Wang, C Ming, ... Scientific data 5 (1), 1-16, 2018 | 344 | 2018 |
Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth L Jin, D Li, GN Alesi, J Fan, HB Kang, Z Lu, TJ Boggon, P Jin, H Yi, ... Cancer cell 27 (2), 257-270, 2015 | 343 | 2015 |
Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease S Rangaraju, EB Dammer, SA Raza, P Rathakrishnan, H Xiao, T Gao, ... Molecular neurodegeneration 13, 1-25, 2018 | 332 | 2018 |
U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer’s disease B Bai, CM Hales, PC Chen, Y Gozal, EB Dammer, JJ Fritz, X Wang, Q Xia, ... Proceedings of the National Academy of Sciences 110 (41), 16562-16567, 2013 | 311 | 2013 |
Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level ECB Johnson, EK Carter, EB Dammer, DM Duong, ES Gerasimov, Y Liu, ... Nature neuroscience 25 (2), 213-225, 2022 | 290 | 2022 |
Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer’s disease Z Zhang, M Song, X Liu, S Su Kang, DM Duong, NT Seyfried, X Cao, ... Nature communications 6 (1), 8762, 2015 | 268 | 2015 |
Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer’s disease L Higginbotham, L Ping, EB Dammer, DM Duong, M Zhou, M Gearing, ... Science advances 6 (43), eaaz9360, 2020 | 244 | 2020 |
Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer’s disease pathogenesis AP Wingo, Y Liu, ES Gerasimov, J Gockley, BA Logsdon, DM Duong, ... Nature genetics 53 (2), 143-146, 2021 | 222 | 2021 |
Polyubiquitin linkage profiles in three models of proteolytic stress suggest the etiology of Alzheimer disease EB Dammer, CH Na, P Xu, NT Seyfried, DM Duong, D Cheng, M Gearing, ... Journal of biological chemistry 286 (12), 10457-10465, 2011 | 215 | 2011 |
Global quantitative analysis of the human brain proteome in Alzheimer’s and Parkinson’s Disease L Ping, DM Duong, L Yin, M Gearing, JJ Lah, AI Levey, NT Seyfried Scientific data 5 (1), 1-12, 2018 | 195 | 2018 |
Deep proteomic network analysis of Alzheimer’s disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease ECB Johnson, EB Dammer, DM Duong, L Yin, M Thambisetty, ... Molecular neurodegeneration 13, 1-22, 2018 | 184 | 2018 |