Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin L Pellegrini, DF Burke, F Von Delft, B Mulloy, TL Blundell Nature 407 (6807), 1029-1034, 2000 | 935 | 2000 |
Insights into DNA recombination from the structure of a RAD51–BRCA2 complex L Pellegrini, DS Yu, T Lo, S Anand, MY Lee, TL Blundell, ... Nature 420 (6913), 287-293, 2002 | 859 | 2002 |
Structure of serum response factor core bound to DNA L Pellegrini, S Tan, TJ Richmond Nature 376 (6540), 490-498, 1995 | 440 | 1995 |
Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells H Dev, TWW Chiang, C Lescale, I de Krijger, AG Martin, D Pilger, ... Nature cell biology 20 (8), 954-965, 2018 | 385 | 2018 |
Role of heparan sulfate in fibroblast growth factor signalling: a structural view L Pellegrini Current opinion in structural biology 11 (5), 629-634, 2001 | 378 | 2001 |
Smarcal1-mediated fork reversal triggers Mre11-dependent degradation of nascent DNA in the absence of Brca2 and stable Rad51 nucleofilaments AM Kolinjivadi, V Sannino, A De Antoni, K Zadorozhny, M Kilkenny, ... Molecular cell 67 (5), 867-881. e7, 2017 | 364 | 2017 |
Crystal structure of an Xrcc4–DNA ligase IV complex BL Sibanda, SE Critchlow, J Begun, XY Pei, SP Jackson, TL Blundell, ... Nature Structural & Molecular Biology 8 (12), 1015-1019, 2001 | 337 | 2001 |
Full‐length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2 DS Shin, L Pellegrini, DS Daniels, B Yelent, L Craig, D Bates, SY David, ... The EMBO journal, 2003 | 320 | 2003 |
Interaction with the BRCA2 C terminus protects RAD51–DNA filaments from disassembly by BRC repeats OR Davies, L Pellegrini Nature structural & molecular biology 14 (6), 475-483, 2007 | 267 | 2007 |
A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome AC Simon, JC Zhou, RL Perera, F van Deursen, C Evrin, ME Ivanova, ... Nature 510 (7504), 293, 2014 | 236 | 2014 |
An iron-sulfur domain of the eukaryotic primase is essential for RNA primer synthesis S Klinge, J Hirst, JD Maman, T Krude, L Pellegrini Nature structural & molecular biology 14 (9), 875-877, 2007 | 203 | 2007 |
The Crystal Structure of Fibroblast Growth Factor (FGF) 19 Reveals Novel Features of the FGF Family and Offers a Structural Basis for Its Unusual Receptor Affinity, NJ Harmer, L Pellegrini, D Chirgadze, J Fernandez-Recio, TL Blundell Biochemistry 43 (3), 629-640, 2004 | 178 | 2004 |
The Pol α-primase complex L Pellegrini The eukaryotic replisome: a guide to protein structure and function, 157-169, 2012 | 150 | 2012 |
Towards a resolution of the stoichiometry of the fibroblast growth factor (FGF)–FGF receptor–heparin complex NJ Harmer, LL Ilag, B Mulloy, L Pellegrini, CV Robinson, TL Blundell Journal of molecular biology 339 (4), 821-834, 2004 | 150 | 2004 |
A molecular model for the role of SYCP3 in meiotic chromosome organisation JL Syrjänen, L Pellegrini, OR Davies elife 3, e02963, 2014 | 148 | 2014 |
Dynamic control of Rad51 recombinase by self-association and interaction with BRCA2 SY David, E Sonoda, S Takeda, CLH Huang, L Pellegrini, TL Blundell, ... Molecular cell 12 (4), 1029-1041, 2003 | 140 | 2003 |
Ctf4 is a hub in the eukaryotic replisome that links multiple CIP-box proteins to the CMG helicase F Villa, AC Simon, MAO Bazan, ML Kilkenny, D Wirthensohn, M Wightman, ... Molecular cell 63 (3), 385-396, 2016 | 134 | 2016 |
Sequence fingerprints in BRCA2 and RAD51: implications for DNA repair and cancer T Lo, L Pellegrini, AR Venkitaraman, TL Blundell DNA repair 2 (9), 1015-1028, 2003 | 134 | 2003 |
3D architecture of DNA Pol α reveals the functional core of multi‐subunit replicative polymerases S Klinge, R Núñez‐Ramírez, O Llorca, L Pellegrini The EMBO journal 28 (13), 1978-1987, 2009 | 127 | 2009 |
Mechanism for priming DNA synthesis by yeast DNA Polymerase α RL Perera, R Torella, S Klinge, ML Kilkenny, JD Maman, L Pellegrini eLife Sciences 2, 2013 | 124 | 2013 |