Articles with public access mandates - David N. FrickLearn more
Available somewhere: 39
Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug
E Mastrangelo, M Pezzullo, T De Burghgraeve, S Kaptein, B Pastorino, ...
Journal of Antimicrobial Chemotherapy 67 (8), 1884-1894, 2012
Mandates: US National Institutes of Health
PSI-7851, a Pronucleotide of β-d-2′-Deoxy-2′-Fluoro-2′-C-Methyluridine Monophosphate, Is a Potent and Pan-Genotype Inhibitor of Hepatitis C Virus …
AM Lam, E Murakami, C Espiritu, HMM Steuer, C Niu, M Keilman, H Bao, ...
Antimicrobial agents and chemotherapy 54 (8), 3187-3196, 2010
Mandates: US National Institutes of Health
Discovering new medicines targeting helicases: challenges and recent progress
WR Shadrick, J Ndjomou, R Kolli, S Mukherjee, AM Hanson, DN Frick
Journal of biomolecular screening 18 (7), 761-781, 2013
Mandates: US National Institutes of Health
Molecular basis for ADP-ribose binding to the Mac1 domain of SARS-CoV-2 nsp3
DN Frick, RS Virdi, N Vuksanovic, N Dahal, NR Silvaggi
Biochemistry 59 (28), 2608-2615, 2020
Mandates: US National Science Foundation, US Department of Energy, US National …
DNA damage alters DNA polymerase δ to a form that exhibits increased discrimination against modified template bases and mismatched primers
X Meng, Y Zhou, S Zhang, EYC Lee, DN Frick, MYWT Lee
Nucleic acids research 37 (2), 647-657, 2009
Mandates: US National Institutes of Health
Ebselen inhibits hepatitis C virus NS3 helicase binding to nucleic acid and prevents viral replication
S Mukherjee, WS Weiner, CE Schroeder, DS Simpson, AM Hanson, ...
ACS chemical biology 9 (10), 2393-2403, 2014
Mandates: US National Institutes of Health
Helicase inhibitors as specifically targeted antiviral therapy for hepatitis C
CA Belon, DN Frick
Future virology 4 (3), 277-293, 2009
Mandates: US National Institutes of Health
Optimization of potent hepatitis C virus NS3 helicase inhibitors isolated from the yellow dyes thioflavine S and primuline
K Li, KJ Frankowski, CA Belon, B Neuenswander, J Ndjomou, AM Hanson, ...
Journal of Medicinal Chemistry 55 (7), 3319-3330, 2012
Mandates: US National Institutes of Health
Analysis of the evolutionary forces in an immunodominant CD8 epitope in hepatitis C virus at a population level
C Neumann-Haefelin, DN Frick, JJ Wang, OG Pybus, S Salloum, ...
Journal of virology 82 (7), 3438-3451, 2008
Mandates: US National Institutes of Health, German Research Foundation
The p12 subunit of human polymerase δ modulates the rate and fidelity of DNA synthesis
X Meng, Y Zhou, EYC Lee, MYWT Lee, DN Frick
Biochemistry 49 (17), 3545-3554, 2010
Mandates: US National Institutes of Health
Monitoring helicase activity with molecular beacons
CA Belon, DN Frick
BioTechniques 45 (4), 433-442, 2008
Mandates: US National Institutes of Health
Benzothiazole and pyrrolone flavivirus inhibitors targeting the viral helicase
NL Sweeney, AM Hanson, S Mukherjee, J Ndjomou, BJ Geiss, JJ Steel, ...
ACS infectious diseases 1 (3), 140-148, 2015
Mandates: US National Institutes of Health
Identification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assays
S Mukherjee, AM Hanson, WR Shadrick, J Ndjomou, NL Sweeney, ...
Nucleic Acids Research 40 (17), 8607-8621, 2012
Mandates: US National Institutes of Health
Cyclophilin B stimulates RNA synthesis by the HCV RNA dependent RNA polymerase
JA Heck, X Meng, DN Frick
Biochemical pharmacology 77 (7), 1173-1180, 2009
Mandates: US National Institutes of Health
Dimerization-driven interaction of hepatitis C virus core protein with NS3 helicase
G Mousseau, S Kota, V Takahashi, DN Frick, AD Strosberg
Journal of General Virology 92 (1), 101-111, 2011
Mandates: US National Institutes of Health
Aurintricarboxylic acid modulates the affinity of hepatitis C virus NS3 helicase for both nucleic acid and ATP
WR Shadrick, S Mukherjee, AM Hanson, NL Sweeney, DN Frick
Biochemistry 52 (36), 6151-6159, 2013
Mandates: US National Institutes of Health
Mechanism and specificity of a symmetrical benzimidazolephenylcarboxamide helicase inhibitor
CA Belon, YD High, TI Lin, F Pauwels, DN Frick
Biochemistry 49 (9), 1822-1832, 2010
Mandates: US National Institutes of Health
Effects of mutagenic and chain-terminating nucleotide analogs on enzymes isolated from hepatitis C virus strains of various genotypes
JA Heck, AMI Lam, N Narayanan, DN Frick
Antimicrobial agents and chemotherapy 52 (6), 1901-1911, 2008
Mandates: US National Institutes of Health
Discovery of drug-like ligands for the Mac1 domain of SARS-CoV-2 Nsp3
RS Virdi, RV Bavisotto, NC Hopper, N Vuksanovic, TR Melkonian, ...
SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (10), 1162-1170, 2020
Mandates: US National Science Foundation, US Department of Energy, US National …
Discovery of the 2-phenyl-4, 5, 6, 7-Tetrahydro-1H-indole as a novel anti-hepatitis C virus targeting scaffold
IA Andreev, D Manvar, ML Barreca, DS Belov, A Basu, NL Sweeney, ...
European journal of medicinal chemistry 96, 250-258, 2015
Mandates: US National Institutes of Health
Publication and funding information is determined automatically by a computer program