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Alessandra De Leo
Alessandra De Leo
Verified email at wistar.org
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Year
Fatty acid transport protein 2 reprograms neutrophils in cancer
F Veglia, VA Tyurin, M Blasi, A De Leo, AV Kossenkov, L Donthireddy, ...
Nature 569 (7754), 73-78, 2019
5242019
Analysis of classical neutrophils and polymorphonuclear myeloid-derived suppressor cells in cancer patients and tumor-bearing mice
F Veglia, A Hashimoto, H Dweep, E Sanseviero, A De Leo, E Tcyganov, ...
Journal of Experimental Medicine 218 (4), 2021
1772021
Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation
L Alinari, KV Mahasenan, F Yan, V Karkhanis, JH Chung, EM Smith, ...
Blood, The Journal of the American Society of Hematology 125 (16), 2530-2543, 2015
1672015
Myeloid cells in glioblastoma microenvironment
A De Leo, A Ugolini, F Veglia
Cells 10 (1), 18, 2020
1172020
Resveratrol inhibits Epstein Barr Virus lytic cycle in Burkitt’s lymphoma cells by affecting multiple molecular targets
A De Leo, G Arena, E Lacanna, G Oliviero, F Colavita, E Mattia
Antiviral research 96 (2), 196-202, 2012
832012
Control of viral latency by episome maintenance proteins
A De Leo, A Calderon, PM Lieberman
Trends in microbiology 28 (2), 150-162, 2020
802020
Identification of MEF2B, EBF1, and IL6R as Direct Gene Targets of Epstein-Barr Virus (EBV) Nuclear Antigen 1 Critical for EBV-Infected B-Lymphocyte Survival
I Tempera, A De Leo, AV Kossenkov, M Cesaroni, H Song, N Dawany, ...
Journal of virology 90 (1), 345-355, 2016
752016
Resveratrol inhibits rhinovirus replication and expression of inflammatory mediators in nasal epithelia
P Mastromarino, D Capobianco, F Cannata, C Nardis, E Mattia, A De Leo, ...
Antiviral research 123, 15-21, 2015
602015
Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus
KD Kim, H Tanizawa, A De Leo, O Vladimirova, A Kossenkov, F Lu, ...
Nature communications 11 (1), 877, 2020
572020
Inhibition of autophagy in EBV-positive Burkitt’s lymphoma cells enhances EBV lytic genes expression and replication
A De Leo, F Colavita, F Ciccosanti, GM Fimia, PM Lieberman, E Mattia
Cell Death and Disease, 2015
502015
Resveratrol Inhibits Proliferation and Survival of Epstein Barr Virus–Infected Burkitt's Lymphoma Cells Depending on Viral Latency Program
A De Leo, G Arena, C Stecca, M Raciti, E Mattia
Molecular Cancer Research 9 (10), 1346-1355, 2011
472011
Inhibition of p38 MAP kinase pathway induces apoptosis and prevents Epstein Barr virus reactivation in Raji cells exposed to lytic cycle inducing compounds
G Matusali, G Arena, A De Leo, L Di Renzo, E Mattia
Molecular cancer 8, 1-11, 2009
442009
BET-inhibitors disrupt Rad21-dependent conformational control of KSHV latency
HS Chen, A De Leo, Z Wang, A Kerekovic, R Hills, PM Lieberman
PLoS pathogens 13 (1), e1006100, 2017
392017
LANA oligomeric architecture is essential for KSHV nuclear body formation and viral genome maintenance during latency
A De Leo, Z Deng, O Vladimirova, HS Chen, J Dheekollu, A Calderon, ...
PLoS Pathogens 15 (1), e1007489, 2019
332019
Phase separation and DAXX redistribution contribute to LANA nuclear body and KSHV genome dynamics during latency and reactivation
O Vladimirova, A De Leo, Z Deng, A Wiedmer, J Hayden, PM Lieberman
PLoS pathogens 17 (1), e1009231, 2021
322021
Deregulation of KSHV latency conformation by ER-stress and caspase-dependent RAD21-cleavage
A De Leo, HS Chen, CCA Hu, PM Lieberman
PLoS pathogens 13 (8), e1006596, 2017
322017
Identification of Mubritinib (TAK 165) as an inhibitor of KSHV driven primary effusion lymphoma via disruption of mitochondrial OXPHOS metabolism
A Calderon, SS Soldan, A De Leo, Z Deng, DM Frase, EM Anderson, ...
Oncotarget 11 (46), 4224, 2020
132020
Defective Epstein-Barr virus genomes and atypical viral gene expression in B-cell lines derived from multiple myeloma patients
F Lu, KA Martin, SS Soldan, AV Kossenkov, P Wickramasinghe, ...
Journal of Virology 95 (13), 10.1128/jvi. 00088-21, 2021
72021
Glucose-driven histone lactylation promotes the immunosuppressive activity of monocyte-derived macrophages in glioblastoma
A De Leo, A Ugolini, X Yu, F Scirocchi, D Scocozza, B Peixoto, A Pace, ...
Immunity 57 (5), 1105-1123. e8, 2024
62024
Down-regulation of proteolytic complexes following EBV activation in BL cells
G Matusali, A De Leo, R Gavioli, L Bertelli, L Di Renzo, E Mattia
Biochemical and biophysical research communications 352 (4), 947-952, 2007
42007
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