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Philippe Bedard
Philippe Bedard
Princess Margaret Cancer Centre
Verified email at uhn.ca
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AACR Project GENIE: powering precision medicine through an international consortium
AACR Project Genie Consortium, AACR Project GENIE Consortium, ...
Cancer discovery 7 (8), 818-831, 2017
13522017
Tumour heterogeneity in the clinic
PL Bedard, AR Hansen, MJ Ratain, LL Siu
Nature 501 (7467), 355-364, 2013
13462013
Tucatinib, trastuzumab, and capecitabine for HER2-positive metastatic breast cancer
RK Murthy, S Loi, A Okines, E Paplomata, E Hamilton, SA Hurvitz, NU Lin, ...
New England Journal of Medicine 382 (7), 597-609, 2020
11312020
Sensitive tumour detection and classification using plasma cell-free DNA methylomes
SY Shen, R Singhania, G Fehringer, A Chakravarthy, MHA Roehrl, ...
Nature 563 (7732), 579-583, 2018
7432018
A framework to rank genomic alterations as targets for cancer precision medicine: the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT)
J Mateo, D Chakravarty, R Dienstmann, S Jezdic, A Gonzalez-Perez, ...
Annals of Oncology 29 (9), 1895-1902, 2018
5732018
Novel patterns of response under immunotherapy
E Borcoman, Y Kanjanapan, S Champiat, S Kato, V Servois, R Kurzrock, ...
Annals of Oncology 30 (3), 385-396, 2019
4532019
Elucidating prognosis and biology of breast cancer arising in young women using gene expression profiling
HA Azim Jr, S Michiels, PL Bedard, SK Singhal, C Criscitiello, M Ignatiadis, ...
Clinical cancer research 18 (5), 1341-1351, 2012
4322012
Intracranial efficacy and survival with tucatinib plus trastuzumab and capecitabine for previously treated HER2-positive breast cancer with brain metastases in the HER2CLIMB trial
NU Lin, V Borges, C Anders, RK Murthy, E Paplomata, E Hamilton, ...
Journal of Clinical Oncology 38 (23), 2610-2619, 2020
4252020
The genetic basis for cancer treatment decisions
JE Dancey, PL Bedard, N Onetto, TJ Hudson
Cell 148 (3), 409-420, 2012
4202012
Small molecules, big impact: 20 years of targeted therapy in oncology
PL Bedard, DM Hyman, MS Davids, LL Siu
The Lancet 395 (10229), 1078-1088, 2020
4172020
Androgen receptor expression and outcomes in early breast cancer: a systematic review and meta-analysis
FE Vera-Badillo, AJ Templeton, P de Gouveia, I Diaz-Padilla, PL Bedard, ...
Journal of the National Cancer Institute 106 (1), djt319, 2014
4032014
Luminal-B breast cancer and novel therapeutic targets
B Tran, PL Bedard
Breast Cancer Research 13 (6), 221, 2011
3462011
Patterns of relapse in patients with clinical stage I testicular cancer managed with active surveillance
C Kollmannsberger, T Tandstad, PL Bedard, G Cohn-Cedermark, ...
Journal of Clinical Oncology 33 (1), 51-57, 2015
3412015
Personalized circulating tumor DNA analysis as a predictive biomarker in solid tumor patients treated with pembrolizumab
SV Bratman, SYC Yang, MAJ Iafolla, Z Liu, AR Hansen, PL Bedard, ...
Nature Cancer 1 (9), 873-881, 2020
3352020
Safety and antitumor activity of pembrolizumab in patients with estrogen receptor–positive/human epidermal growth factor receptor 2–negative advanced breast cancer
HS Rugo, JP Delord, SA Im, PA Ott, SA Piha-Paul, PL Bedard, J Sachdev, ...
Clinical Cancer Research 24 (12), 2804-2811, 2018
3222018
A phase Ib dose-escalation study of the oral pan-PI3K inhibitor buparlisib (BKM120) in combination with the oral MEK1/2 inhibitor trametinib (GSK1120212) in patients with …
PL Bedard, J Tabernero, F Janku, ZA Wainberg, L Paz-Ares, ...
Clinical Cancer Research 21 (4), 730-738, 2015
3192015
International guidelines for management of metastatic breast cancer: combination vs sequential single-agent chemotherapy
F Cardoso, PL Bedard, EP Winer, O Pagani, E Senkus-Konefka, ...
Journal of the National Cancer Institute 101 (17), 1174-1181, 2009
3102009
AKT Inhibition in Solid Tumors With AKT1 Mutations
DM Hyman, LM Smyth, MTA Donoghue, SN Westin, PL Bedard, EJ Dean, ...
Journal of Clinical Oncology 35 (20), 2251-2259, 2017
2942017
Molecular profiling of advanced solid tumors and patient outcomes with genotype-matched clinical trials: the Princess Margaret IMPACT/COMPACT trial
TL Stockley, AM Oza, HK Berman, NB Leighl, JJ Knox, FA Shepherd, ...
Genome medicine 8, 1-12, 2016
2492016
Phase I/Ib clinical trial of sabatolimab, an anti–TIM-3 antibody, alone and in combination with spartalizumab, an anti–PD-1 antibody, in advanced solid tumors
G Curigliano, H Gelderblom, N Mach, T Doi, D Tai, PM Forde, ...
Clinical Cancer Research 27 (13), 3620-3629, 2021
2252021
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