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Grennady Wirjanata
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A novel multiple-stage antimalarial agent that inhibits protein synthesis
B Baragaña, I Hallyburton, MCS Lee, NR Norcross, R Grimaldi, TD Otto, ...
Nature 522 (7556), 315-320, 2015
4612015
Quinolone-3-diarylethers: a new class of antimalarial drug
A Nilsen, AN LaCrue, KL White, IP Forquer, RM Cross, J Marfurt, ...
Science translational medicine 5 (177), 177ra37-177ra37, 2013
2522013
Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay
JM Dziekan, H Yu, D Chen, L Dai, G Wirjanata, A Larsson, N Prabhu, ...
Science translational medicine 11 (473), eaau3174, 2019
1902019
KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment, and prevention of disease transmission
KL Kuhen, AK Chatterjee, M Rottmann, K Gagaring, R Borboa, ...
Antimicrobial agents and chemotherapy 58 (9), 5060-5067, 2014
1752014
Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum
AB Vaidya, JM Morrisey, Z Zhang, S Das, TM Daly, TD Otto, NJ Spillman, ...
Nature communications 5 (1), 5521, 2014
1542014
Cellular thermal shift assay for the identification of drug–target interactions in the Plasmodium falciparum proteome
JM Dziekan, G Wirjanata, L Dai, KD Go, H Yu, YT Lim, L Chen, LC Wang, ...
Nature protocols 15 (6), 1881-1921, 2020
902020
A triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with improved drug-like properties for treatment and prevention of malaria
MA Phillips, KL White, S Kokkonda, X Deng, J White, F El Mazouni, ...
ACS infectious diseases 2 (12), 945-957, 2016
882016
A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance
PM O’Neill, RK Amewu, SA Charman, S Sabbani, NF Gnädig, J Straimer, ...
Nature Communications 8 (1), 15159, 2017
712017
UCT943, a next-generation Plasmodium falciparum PI4K inhibitor preclinical candidate for the treatment of malaria
C Brunschwig, N Lawrence, D Taylor, E Abay, M Njoroge, GS Basarab, ...
Antimicrobial agents and chemotherapy 62 (9), 10.1128/aac. 00012-18, 2018
682018
Submicroscopic and Asymptomatic Plasmodium Parasitaemia Associated with Significant Risk of Anaemia in Papua, Indonesia
Z Pava, FH Burdam, I Handayuni, L Trianty, RAS Utami, YK Tirta, ...
PloS one 11 (10), e0165340, 2016
652016
Characterization of novel antimalarial compound ACT-451840: preclinical assessment of activity and dose–efficacy modeling
A Le Bihan, R de Kanter, I Angulo-Barturen, C Binkert, C Boss, R Brun, ...
PLoS medicine 13 (10), e1002138, 2016
462016
Comparative Ex Vivo Activity of Novel Endoperoxides in Multidrug-Resistant Plasmodium falciparum and P. vivax
J Marfurt, F Chalfein, P Prayoga, F Wabiser, G Wirjanata, B Sebayang, ...
Antimicrobial agents and chemotherapy 56 (10), 5258-5263, 2012
452012
Effective Preparation of Plasmodium vivax Field Isolates for High-Throughput Whole Genome Sequencing
S Auburn, J Marfurt, G Maslen, S Campino, V Ruano Rubio, M Manske, ...
PLoS One 8 (1), e53160, 2013
372013
The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance
JM Murithi, C Pascal, J Bath, X Boulenc, NF Gnädig, CFA Pasaje, ...
Science translational medicine 13 (603), eabg6013, 2021
342021
Expression of Plasmodium vivax crt-o Is Related to Parasite Stage but Not Ex Vivo Chloroquine Susceptibility
Z Pava, I Handayuni, G Wirjanata, S To, L Trianty, R Noviyanti, ...
Antimicrobial agents and chemotherapy 60 (1), 361-367, 2016
322016
Potent Ex Vivo Activity of Naphthoquine and Methylene Blue against Drug-Resistant Clinical Isolates of Plasmodium falciparum and Plasmodium vivax
G Wirjanata, BF Sebayang, F Chalfein, Prayoga, I Handayuni, L Trianty, ...
Antimicrobial Agents and Chemotherapy 59 (10), 6117-6124, 2015
272015
A comprehensive RNA handling and transcriptomics guide for high-throughput processing of Plasmodium blood-stage samples
M Kucharski, J Tripathi, S Nayak, L Zhu, G Wirjanata, RW Van Der Pluijm, ...
Malaria Journal 19, 1-16, 2020
232020
3, 3′-Disubstituted 5, 5′-bi (1, 2, 4-triazine) derivatives with potent in vitro and in vivo antimalarial activity
L Xue, DH Shi, JR Harjani, F Huang, JG Beveridge, T Dingjan, K Ban, ...
Journal of medicinal chemistry 62 (5), 2485-2498, 2019
192019
Passively versus actively detected malaria: similar genetic diversity but different complexity of infection
Z Pava, I Handayuni, L Trianty, RAS Utami, YK Tirta, AM Puspitasari, ...
The American journal of tropical medicine and hygiene 97 (6), 1788, 2017
192017
Quinolone-3-diarylethers: a new class of antimalarial drug. Sci Transl Med 5: 177ra37
A Nilsen, AN LaCrue, KL White, IP Forquer, RM Cross, J Marfurt, ...
192013
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