Many cuts to ruin: a comprehensive update of caspase substrates U Fischer, RU Jänicke, K Schulze-Osthoff Cell Death & Differentiation 10 (1), 76-100, 2003 | 1533 | 2003 |
Apoptosis signaling by death receptors K Schulze‐Osthoff, D Ferrari, M Los, S Wesselborg, ME Peter European journal of biochemistry 254 (3), 439-459, 1998 | 1464 | 1998 |
Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal K Lauber, E Bohn, SM Kröber, Y Xiao, SG Blumenthal, RK Lindemann, ... Cell 113 (6), 717-730, 2003 | 1154 | 2003 |
Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation. K Schulze-Osthoff, AC Bakker, B Vanhaesebroeck, R Beyaert, WA Jacob, ... Journal of Biological Chemistry 267 (8), 5317-5323, 1992 | 1134 | 1992 |
Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-kappa B and AP-1. H Schenk, M Klein, W Erdbrügger, W Dröge, K Schulze-Osthoff Proceedings of the National Academy of Sciences 91 (5), 1672-1676, 1994 | 878 | 1994 |
Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis M Los, MV Craen, LC Penning, H Schenk, M Westendorp, PA Baeuerle, ... Nature 375 (6526), 81-83, 1995 | 824 | 1995 |
T-helper-1-cell cytokines drive cancer into senescence H Braumüller, T Wieder, E Brenner, S Aßmann, M Hahn, M Alkhaled, ... Nature 494 (7437), 361-365, 2013 | 821 | 2013 |
Small stress proteins as novel regulators of apoptosis: heat shock protein 27 blocks Fas/APO-1-and staurosporine-induced cell death P Mehlen, K Schulze-Osthoff, AP Arrigo Journal of Biological Chemistry 271 (28), 16510-16514, 1996 | 815 | 1996 |
PARP is important for genomic stability but dispensable in apoptosis ZQ Wang, L Stingl, C Morrison, M Jantsch, M Los, K Schulze-Osthoff, ... Genes & development 11 (18), 2347-2358, 1997 | 762 | 1997 |
Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene‐inductive effects of TNF. K Schulze‐Osthoff, R Beyaert, V Vandevoorde, G Haegeman, W Fiers The EMBO journal 12 (8), 3095-3104, 1993 | 702 | 1993 |
Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling M Los, M Mozoluk, D Ferrari, A Stepczynska, C Stroh, A Renz, Z Herceg, ... Molecular biology of the cell 13 (3), 978-988, 2002 | 658 | 2002 |
Functions of glutathione and glutathione disulfide in immunology and immunopathology W Dröge, K Schulze‐Osthoff, S Mihm, D Galter, H Schenk, HP Eck, S Roth, ... The FASEB journal 8 (14), 1131-1138, 1994 | 625 | 1994 |
Reduced Loading of Intracellular Ca2+ Stores and Downregulation of Capacitative Ca2+Influx in Bcl-2–Overexpressing Cells P Pinton, D Ferrari, P Magalhães, K Schulze-Osthoff, F Di Virgilio, ... The Journal of cell biology 148 (5), 857-862, 2000 | 604 | 2000 |
The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice M Los, S Wesselborg, K Schulze-Osthoff Immunity 10 (6), 629-639, 1999 | 588 | 1999 |
Transdifferentiation of vascular smooth muscle cells to macrophage-like cells during atherogenesis S Feil, B Fehrenbacher, R Lukowski, F Essmann, K Schulze-Osthoff, ... Circulation research 115 (7), 662-667, 2014 | 580 | 2014 |
Cell nucleus and DNA fragmentation are not required for apoptosis. K Schulze-Osthoff, H Walczak, W Dröge, PH Krammer The Journal of cell biology 127 (1), 15-20, 1994 | 566 | 1994 |
Cancer stem cell markers in common cancers–therapeutic implications T Klonisch, E Wiechec, S Hombach-Klonisch, SR Ande, S Wesselborg, ... Trends in molecular medicine 14 (10), 450-460, 2008 | 523 | 2008 |
HIV‐1 Tat potentiates TNF‐induced NF‐kappa B activation and cytotoxicity by altering the cellular redox state. MO Westendorp, VA Shatrov, K Schulze‐Osthoff, R Frank, M Kraft, M Los, ... The EMBO journal 14 (3), 546-554, 1995 | 488 | 1995 |
Sesquiterpene lactones specifically inhibit activation of NF-κB by preventing the degradation of IκB-α and IκB-β SP Hehner, M Heinrich, PM Bork, M Vogt, F Ratter, V Lehmann, ... Journal of Biological Chemistry 273 (3), 1288-1297, 1998 | 486 | 1998 |
Regulation of apoptosis by alternative pre-mRNA splicing C Schwerk, K Schulze-Osthoff Molecular cell 19 (1), 1-13, 2005 | 471 | 2005 |