Endotoxin leads to rapid subcellular re-localization of hepatic RXRα: a novel mechanism for reduced hepatic gene expression in inflammation R Ghose, TL Zimmerman, S Thevananther, SJ Karpen Nuclear receptor 2, 1-9, 2004 | 165 | 2004 |
Nuclear export of retinoid X receptor α in response to interleukin-1β-mediated cell signaling: roles for JNK and SER260 TL Zimmerman, S Thevananther, R Ghose, AR Burns, SJ Karpen Journal of Biological Chemistry 281 (22), 15434-15440, 2006 | 157 | 2006 |
Role of high-fat diet in regulation of gene expression of drug metabolizing enzymes and transporters R Ghose, O Omoluabi, A Gandhi, P Shah, K Strohacker, KC Carpenter, ... Life sciences 89 (1-2), 57-64, 2011 | 136 | 2011 |
Induction of TAK (Cyclin T1/P-TEFb) in Purified Resting CD4+ T Lymphocytes by Combination of Cytokines R Ghose, LY Liou, CH Herrmann, AP Rice Journal of Virology 75 (23), 11336-11343, 2001 | 131 | 2001 |
Clarifying busulfan metabolism and drug interactions to support new therapeutic drug monitoring strategies: a comprehensive review AL Myers, JD Kawedia, RE Champlin, MA Kramer, Y Nieto, R Ghose, ... Expert opinion on drug metabolism & toxicology 13 (9), 901-923, 2017 | 100 | 2017 |
Drug disposition in pathophysiological conditions A Gandhi, B Moorthy, R Ghose Current drug metabolism 13 (9), 1327-1344, 2012 | 92 | 2012 |
Role of c-Jun N-terminal kinase (JNK) in regulating tumor necrosis factor-alpha (TNF-α) mediated increase of acetaminophen (APAP) and chlorpromazine (CPZ) toxicity in murine … A Gandhi, T Guo, R Ghose The Journal of toxicological sciences 35 (2), 163-173, 2010 | 60 | 2010 |
Antiapoptotic function of Cdk9 (TAK/P-TEFb) in U937 promonocytic cells SM Foskett, R Ghose, DN Tang, DE Lewis, AP Rice Journal of Virology 75 (3), 1220-1228, 2001 | 59 | 2001 |
Regulation of drug-metabolizing enzymes in infectious and inflammatory disease: Implications for biologics–small molecule drug interactions P Mallick, G Taneja, B Moorthy, R Ghose Expert opinion on drug metabolism & toxicology 13 (6), 605-616, 2017 | 48 | 2017 |
Rosiglitazone attenuates suppression of RXRα-dependent gene expression in inflamed liver R Ghose, J Mulder, RJ von Furstenberg, S Thevananther, F Kuipers, ... Journal of hepatology 46 (1), 115-123, 2007 | 44 | 2007 |
Potential role of drug metabolizing enzymes in chemotherapy-induced gastrointestinal toxicity and hepatotoxicity G Tao, J Huang, B Moorthy, C Wang, M Hu, S Gao, R Ghose Expert opinion on drug metabolism & toxicology 16 (11), 1109-1124, 2020 | 43 | 2020 |
Regulation of gene expression of hepatic drug metabolizing enzymes and transporters by the Toll-like receptor 2 ligand, lipoteichoic acid R Ghose, T Guo, N Haque Archives of biochemistry and biophysics 481 (1), 123-130, 2009 | 40 | 2009 |
Role of constitutive androstane receptor in Toll-like receptor-mediated regulation of gene expression of hepatic drug-metabolizing enzymes and transporters P Shah, T Guo, DD Moore, R Ghose Drug Metabolism and Disposition 42 (1), 172-181, 2014 | 39 | 2014 |
Regulation of hepatic drug-metabolizing enzyme genes by Toll-like receptor 4 signaling is independent of Toll-interleukin 1 receptor domain-containing adaptor protein R Ghose, D White, T Guo, J Vallejo, SJ Karpen Drug metabolism and disposition 36 (1), 95-101, 2008 | 39 | 2008 |
Differential role of Toll-interleukin 1 receptor domain-containing adaptor protein in Toll-like receptor 2-mediated regulation of gene expression of hepatic cytokines and drug … R Ghose, T Guo, JG Vallejo, A Gandhi Drug metabolism and disposition 39 (5), 874-881, 2011 | 36 | 2011 |
CYP3A‐dependent drug metabolism is reduced in bacterial inflammation in mice AS Gandhi, T Guo, P Shah, B Moorthy, DSL Chow, M Hu, R Ghose British journal of pharmacology 166 (7), 2176-2187, 2012 | 33 | 2012 |
Neratinib in HER2-positive breast cancer patients R Paranjpe, D Basatneh, G Tao, C De Angelis, S Noormohammed, ... Annals of Pharmacotherapy 53 (6), 612-620, 2019 | 31 | 2019 |
Irinotecan-mediated diarrhea is mainly correlated with intestinal exposure to SN-38: Critical role of gut Ugt R Sun, L Zhu, L Li, W Song, X Gong, X Qi, Y Wang, R Ghose, S Gao, M Hu, ... Toxicology and applied pharmacology 398, 115032, 2020 | 30 | 2020 |
Chlorpromazine-induced hepatotoxicity during inflammation is mediated by TIRAP-dependent signaling pathway in mice A Gandhi, T Guo, P Shah, B Moorthy, R Ghose Toxicology and applied pharmacology 266 (3), 430-438, 2013 | 30 | 2013 |
In vivo dynamics of carbapenem-resistant Pseudomonas aeruginosa selection after suboptimal dosing VH Tam, KR Ledesma, AN Schilling, TP Lim, Z Yuan, R Ghose, RE Lewis Diagnostic microbiology and infectious disease 64 (4), 427-433, 2009 | 24 | 2009 |