| Exchange protein directly activated by cAMP (epac): a multidomain cAMP mediator in the regulation of diverse biological functions M Schmidt, FJ Dekker, H Maarsingh Pharmacological reviews 65 (2), 670-709, 2013 | 352 | 2013 |
| Arginase and asthma: novel insights into nitric oxide homeostasis and airway hyperresponsiveness H Meurs, H Maarsingh, J Zaagsma Trends in Pharmacological Sciences 24 (9), 450-455, 2003 | 249 | 2003 |
| Airway structural components drive airway smooth muscle remodeling in asthma BGJ Dekkers, H Maarsingh, H Meurs, R Gosens Proceedings of the American Thoracic Society 6 (8), 683-692, 2009 | 221 | 2009 |
| Increased arginase activity underlies allergen‐induced deficiency of cNOS‐derived nitric oxide and airway hyperresponsiveness H Meurs, S McKay, H Maarsingh, MAM Hamer, L Macic, N Molendijk, ... British journal of pharmacology 136 (3), 391-398, 2002 | 184 | 2002 |
| Arginase and pulmonary diseases H Maarsingh, T Pera, H Meurs Naunyn-Schmiedeberg's archives of pharmacology 378, 171-184, 2008 | 182 | 2008 |
| Arginase: a key enzyme in the pathophysiology of allergic asthma opening novel therapeutic perspectives H Maarsingh, J Zaagsma, H Meurs British journal of pharmacology 158 (3), 652-664, 2009 | 178 | 2009 |
| Histone acetyltransferases are crucial regulators in NF-κB mediated inflammation M Ghizzoni, HJ Haisma, H Maarsingh, FJ Dekker Drug discovery today 16 (11-12), 504-511, 2011 | 171 | 2011 |
| Tiotropium inhibits pulmonary inflammation and remodelling in a guinea pig model of COPD T Pera, A Zuidhof, J Valadas, M Smit, RG Schoemaker, R Gosens, ... European Respiratory Journal 38 (4), 789-796, 2011 | 152 | 2011 |
| Arginase inhibition protects against allergen-induced airway obstruction, hyperresponsiveness, and inflammation H Maarsingh, AB Zuidhof, IST Bos, M van Duin, JL Boucher, J Zaagsma, ... American journal of respiratory and critical care medicine 178 (6), 565-573, 2008 | 139 | 2008 |
| Arginase strongly impairs neuronal nitric oxide-mediated airway smooth muscle relaxation in allergic asthma H Maarsingh, J Leusink, IST Bos, J Zaagsma, H Meurs Respiratory research 7, 1-7, 2006 | 139 | 2006 |
| Increased arginase activity contributes to airway remodelling in chronic allergic asthma H Maarsingh, BGJ Dekkers, AB Zuidhof, IST Bos, MH Menzen, T Klein, ... European Respiratory Journal 38 (2), 318-328, 2011 | 122 | 2011 |
| Muscarinic receptors on airway mesenchymal cells: novel findings for an ancient target H Meurs, BGJ Dekkers, H Maarsingh, AJ Halayko, J Zaagsma, R Gosens Pulmonary pharmacology & therapeutics 26 (1), 145-155, 2013 | 107 | 2013 |
| Arginase 1 and arginase 2 variations associate with asthma, asthma severity and β2 agonist and steroid response JM Vonk, DS Postma, H Maarsingh, M Bruinenberg, GH Koppelman, ... Pharmacogenetics and genomics 20 (3), 179-186, 2010 | 106 | 2010 |
| Epac as a novel effector of airway smooth muscle relaxation SS Roscioni, H Maarsingh, CRS Elzinga, J Schuur, M Menzen, ... Journal of cellular and molecular medicine 15 (7), 1551-1563, 2011 | 104 | 2011 |
| Bronchoconstriction induces TGF-β release and airway remodelling in guinea pig lung slices TA Oenema, H Maarsingh, M Smit, GMM Groothuis, H Meurs, R Gosens PLoS One 8 (6), e65580, 2013 | 101 | 2013 |
| Anti-inflammatory role of the cAMP effectors Epac and PKA: implications in chronic obstructive pulmonary disease A Oldenburger, SS Roscioni, E Jansen, MH Menzen, AJ Halayko, ... PloS one 7 (2), e31574, 2012 | 98 | 2012 |
| Arginase inhibition prevents inflammation and remodeling in a guinea pig model of chronic obstructive pulmonary disease T Pera, AB Zuidhof, M Smit, MH Menzen, T Klein, G Flik, J Zaagsma, ... Journal of Pharmacology and Experimental Therapeutics 349 (2), 229-238, 2014 | 87 | 2014 |
| Arginine homeostasis in allergic asthma H Maarsingh, J Zaagsma, H Meurs European journal of pharmacology 585 (2-3), 375-384, 2008 | 86 | 2008 |
| A-kinase anchoring proteins contribute to loss of E-cadherin and bronchial epithelial barrier by cigarette smoke A Oldenburger, WJ Poppinga, F Kos, HG de Bruin, WF Rijks, IH Heijink, ... American Journal of Physiology-Cell Physiology 306 (6), C585-C597, 2014 | 73 | 2014 |
| Arginase attenuates inhibitory nonadrenergic noncholinergic nerve-induced nitric oxide generation and airway smooth muscle relaxation H Maarsingh, MA Tio, J Zaagsma, H Meurs Respiratory Research 6, 1-6, 2005 | 69 | 2005 |