Degradation of a mutant secretory protein, α1-antitrypsin Z, in the endoplasmic reticulum requires proteasome activity D Qu, JH Teckman, S Omura, DH Perlmutter Journal of Biological Chemistry 271 (37), 22791-22795, 1996 | 425 | 1996 |
The crystal structure of the endothelial protein C receptor and a bound phospholipid V Oganesyan, N Oganesyan, S Terzyan, D Qu, Z Dauter, NL Esmon, ... Journal of Biological Chemistry 277 (28), 24851-24854, 2002 | 238 | 2002 |
Metalloproteolytic release of endothelial cell protein C receptor J Xu, D Qu, NL Esmon, CT Esmon Journal of Biological Chemistry 275 (8), 6038-6044, 2000 | 227 | 2000 |
Endothelial protein C receptor CT Esmon, J Xu, J Gu, D Qu, Z Laszik, G Ferrell, DJ Stearns-Kurosawa, ... Thrombosis and haemostasis 82 (2), 251-258, 1999 | 184 | 1999 |
Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism SM Sureban, R May, FG Mondalek, D Qu, S Ponnurangam, P Pantazis, ... Journal of nanobiotechnology 9 (1), 40, 2011 | 176 | 2011 |
DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer SM Sureban, R May, D Qu, N Weygant, P Chandrakesan, N Ali, ... PloS one 8 (9), e73940, 2013 | 155 | 2013 |
Molecular pathogenesis of liver disease in α1‐antitrypsin deficiency JH Teckman, D Qu, DH Perlmutter Hepatology 24 (6), 1504-1516, 1996 | 151 | 1996 |
Regulation and functions of the protein C anticoagulant pathway CT Esmon, JM Gu, J Xu, D Qu, DJ Stearns-Kurosawa, S Kurosawa Haematologica 84 (4), 363-368, 1999 | 145 | 1999 |
Regulated endothelial protein C receptor shedding is mediated by tumor necrosis factor‐α converting enzyme/ADAM17 D Qu, Y Wang, NL Esmon, CT Esmon Journal of Thrombosis and Haemostasis 5 (2), 395-402, 2007 | 132 | 2007 |
Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1 N Weygant, D Qu, WL Berry, R May, P Chandrakesan, DB Owen, ... Molecular cancer 13 (1), 103, 2014 | 130 | 2014 |
XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism SM Sureban, R May, N Weygant, D Qu, P Chandrakesan, ... Cancer letters 351 (1), 151-161, 2014 | 126 | 2014 |
Dclk1, a tumor stem cell marker, regulates pro-survival signaling and self-renewal of intestinal tumor cells P Chandrakesan, J Yao, D Qu, R May, N Weygant, Y Ge, N Ali, ... Molecular cancer 16 (1), 30, 2017 | 112 | 2017 |
The Ser219–> Gly dimorphism of the endothelial protein C receptor contributes to the higher soluble protein levels observed in individuals with the A3 haplotype D Qu, Y Wang, Y Song, NL Esmon, CT Esmon Journal of Thrombosis and Haemostasis 4 (1), 229-235, 2006 | 111 | 2006 |
CD73-generated adenosine restricts lymphocyte migration into draining lymph nodes M Takedachi, D Qu, Y Ebisuno, H Oohara, ML Joachims, ST McGee, ... The Journal of Immunology 180 (9), 6288-6296, 2008 | 110 | 2008 |
A 23bp insertion in the endothelial protein C receptor (EPCR) gene impairs EPCR function E Biguzzi, G Merati, PCY Liaw, P Bucciarelli, N Oganesyan, D Qu, JM Gu, ... Thrombosis and haemostasis 86 (4), 945-948, 2001 | 105 | 2001 |
DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma N Weygant, D Qu, R May, RM Tierney, WL Berry, L Zhao, S Agarwal, ... Cancer Research 75 (15 Supplement), 4374-4374, 2015 | 98 | 2015 |
Brief report: Dclk1 deletion in tuft cells results in impaired epithelial repair after radiation injury R May, D Qu, N Weygant, P Chandrakesan, N Ali, SA Lightfoot, L Li, ... Stem cells 32 (3), 822-827, 2014 | 92 | 2014 |
Identification of the putative intestinal stem cell marker doublecortin and CaM kinase‐like‐1 in Barrett's esophagus and esophageal adenocarcinoma KJ Vega, R May, SM Sureban, SA Lightfoot, D Qu, A Reed, N Weygant, ... Journal of gastroenterology and hepatology 27 (4), 773-780, 2012 | 86 | 2012 |
DCLK1 facilitates intestinal tumor growth via enhancing pluripotency and epithelial mesenchymal transition P Chandrakesan, N Weygant, R May, D Qu, HR Chinthalapally, ... Oncotarget 5 (19), 9269, 2014 | 84 | 2014 |
Ablation of doublecortin-like kinase 1 in the colonic epithelium exacerbates dextran sulfate sodium-induced colitis D Qu, N Weygant, R May, P Chandrakesan, M Madhoun, N Ali, ... PloS one 10 (8), e0134212, 2015 | 73 | 2015 |