Articles with public access mandates - Darren MoncktonLearn more
Not available anywhere: 1
Survival and CTG repeat expansion in adults with myotonic dystrophy type 1
WJ Groh, MR Groh, C Shen, DG Monckton, CL Bodkin, RM Pascuzzi
Muscle & nerve 43 (5), 648-651, 2011
Mandates: US National Institutes of Health
Available somewhere: 62
CAG repeat not polyglutamine length determines timing of Huntington’s disease onset
JM Lee, K Correia, J Loupe, KH Kim, D Barker, EP Hong, MJ Chao, ...
Cell 178 (4), 887-900. e14, 2019
Mandates: US National Institutes of Health, UK Medical Research Council
Consensus-based care recommendations for adults with myotonic dystrophy type 1
T Ashizawa, C Gagnon, WJ Groh, L Gutmann, NE Johnson, G Meola, ...
Neurology: Clinical Practice 8 (6), 507-520, 2018
Mandates: US National Institutes of Health
MSH3 polymorphisms and protein levels affect CAG repeat instability in Huntington's disease mice
S Tomé, K Manley, JP Simard, GW Clark, MM Slean, M Swami, ...
PLoS genetics 9 (2), e1003280, 2013
Mandates: US National Institutes of Health, Canadian Institutes of Health Research
MSH3 modifies somatic instability and disease severity in Huntington’s and myotonic dystrophy type 1
M Flower, V Lomeikaite, M Ciosi, S Cumming, F Morales, K Lo, ...
Brain 142 (7), 1876-1886, 2019
Mandates: Alzheimers's UK, UK Medical Research Council, Wellcome Trust
A genetic association study of glutamine-encoding DNA sequence structures, somatic CAG expansion, and DNA repair gene variants, with Huntington disease clinical outcomes
M Ciosi, A Maxwell, SA Cumming, DJH Moss, AM Alshammari, MD Flower, ...
EBioMedicine 48, 568-580, 2019
Mandates: UK Medical Research Council, National Institute for Health Research, UK …
CRISPR/Cas9-induced (CTG⋅ CAG) n repeat instability in the myotonic dystrophy type 1 locus: implications for therapeutic genome editing
EL Van Agtmaal, LM André, M Willemse, SA Cumming, ID Van Kessel, ...
Molecular therapy 25 (1), 24-43, 2017
Mandates: Netherlands Organisation for Health Research and Development
Cognitive behavioural therapy with optional graded exercise therapy in patients with severe fatigue with myotonic dystrophy type 1: a multicentre, single-blind, randomised trial
K Okkersen, C Jimenez-Moreno, S Wenninger, F Daidj, J Glennon, ...
The Lancet Neurology 17 (8), 671-680, 2018
Mandates: Netherlands Organisation for Scientific Research, Chief Scientist Office …
De novo repeat interruptions are associated with reduced somatic instability and mild or absent clinical features in myotonic dystrophy type 1
SA Cumming, MJ Hamilton, Y Robb, H Gregory, C McWilliam, A Cooper, ...
European Journal of Human Genetics 26 (11), 1635-1647, 2018
Mandates: Wellcome Trust
Huntington’s disease pathogenesis: Two sequential components
EP Hong, ME MacDonald, VC Wheeler, L Jones, P Holmans, M Orth, ...
Journal of Huntington's disease 10 (1), 35-51, 2021
Mandates: US National Institutes of Health, UK Medical Research Council
DNA methylation study of Huntington’s disease and motor progression in patients and in animal models
AT Lu, P Narayan, MJ Grant, P Langfelder, N Wang, S Kwak, H Wilkinson, ...
Nature communications 11 (1), 4529, 2020
Mandates: US National Institutes of Health
Genetic and functional analyses point to FAN1 as the source of multiple Huntington disease modifier effects
KH Kim, EP Hong, JW Shin, MJ Chao, J Loupe, T Gillis, JS Mysore, ...
The American Journal of Human Genetics 107 (1), 96-110, 2020
Mandates: US National Institutes of Health, UK Medical Research Council
Allele length of the DMPK CTG repeat is a predictor of progressive myotonic dystrophy type 1 phenotypes
G Overend, C Légaré, J Mathieu, L Bouchard, C Gagnon, DG Monckton
Human Molecular Genetics 28 (13), 2245-2254, 2019
Mandates: Canadian Institutes of Health Research, Fonds de recherche du Québec - Santé
Genetic modifiers of Huntington disease differentially influence motor and cognitive domains
JM Lee, Y Huang, M Orth, T Gillis, J Siciliano, E Hong, JS Mysore, ...
The American Journal of Human Genetics 109 (5), 885-899, 2022
Mandates: US National Institutes of Health, UK Medical Research Council
Identification and characterization of 5′ CCG interruptions in complex DMPK expanded alleles
A Botta, G Rossi, M Marcaurelio, L Fontana, MR D'Apice, F Brancati, ...
European Journal of Human Genetics 25 (2), 257-261, 2017
Mandates: Government of Italy
Exome sequencing of individuals with Huntington’s disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset
B McAllister, J Donaldson, CS Binda, S Powell, U Chughtai, G Edwards, ...
Nature neuroscience 25 (4), 446-457, 2022
Mandates: US National Institutes of Health, Alzheimers's UK, UK Medical Research …
Disease burden of myotonic dystrophy type 1
E Landfeldt, N Nikolenko, C Jimenez-Moreno, S Cumming, DG Monckton, ...
Journal of neurology 266, 998-1006, 2019
Mandates: UK Medical Research Council, National Institute for Health Research, UK
Disease-associated CAG· CTG triplet repeats expand rapidly in non-dividing mouse cells, but cell cycle arrest is insufficient to drive expansion
M Gomes-Pereira, JD Hilley, F Morales, B Adam, HE James, ...
Nucleic acids research 42 (11), 7047-7056, 2014
Mandates: Wellcome Trust
Genetic risk underlying psychiatric and cognitive symptoms in Huntington’s disease
N Ellis, A Tee, B McAllister, T Massey, D McLauchlan, T Stone, K Correia, ...
Biological Psychiatry 87 (9), 857-865, 2020
Mandates: US National Institutes of Health, German Research Foundation, UK Medical …
Structural white matter networks in myotonic dystrophy type 1
M van Dorst, K Okkersen, RPC Kessels, FJA Meijer, DG Monckton, ...
NeuroImage: Clinical 21, 101615, 2019
Mandates: Dutch Heart Foundation
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